LOC607729 (A disintegrin and metallopeptidase domain 3-like) - Rat Genome Database

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Gene: LOC607729 (A disintegrin and metallopeptidase domain 3-like) Canis lupus familiaris
Analyze
Symbol: LOC607729
Name: A disintegrin and metallopeptidase domain 3-like
RGD ID: 12323084
Description: ENCODES a protein that exhibits metalloendopeptidase activity (inferred); INVOLVED IN binding of sperm to zona pellucida (inferred); cell adhesion (inferred); male gonad development (inferred); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: disintegrin and metalloproteinase domain-containing protein 18-like
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11625,927,326 - 26,021,009 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1626,449,011 - 26,542,660 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01627,760,999 - 27,851,012 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11626,052,365 - 26,146,069 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01626,615,376 - 26,709,205 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01626,666,497 - 26,760,947 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Variants

.
Variants in LOC607729
835 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 2
Medium 6 1
Low 3 2 16 3 4 1 12 10 5
Below cutoff 2 3 6 6 3 6 2 5

Sequence


Reference Sequences
RefSeq Acc Id: XM_014120085   ⟹   XP_013975560
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11625,927,326 - 26,021,009 (-)NCBI
Dog10K_Boxer_Tasha1626,449,011 - 26,542,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022404023   ⟹   XP_022259731
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11625,927,326 - 26,020,319 (-)NCBI
Dog10K_Boxer_Tasha1626,449,011 - 26,541,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038497563   ⟹   XP_038353491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11626,052,365 - 26,146,069 (-)NCBI
RefSeq Acc Id: XM_038497564   ⟹   XP_038353492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11626,052,365 - 26,145,389 (-)NCBI
RefSeq Acc Id: XM_038560013   ⟹   XP_038415941
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01626,666,497 - 26,760,947 (-)NCBI
RefSeq Acc Id: XM_038560014   ⟹   XP_038415942
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01626,666,497 - 26,760,250 (-)NCBI
RefSeq Acc Id: XM_038624058   ⟹   XP_038479986
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01626,615,376 - 26,709,205 (-)NCBI
RefSeq Acc Id: XM_038624059   ⟹   XP_038479987
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01626,615,376 - 26,708,548 (-)NCBI
RefSeq Acc Id: XM_038689808   ⟹   XP_038545736
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01627,760,999 - 27,851,012 (-)NCBI
RefSeq Acc Id: XM_038689809   ⟹   XP_038545737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01627,760,999 - 27,850,312 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013975560   ⟸   XM_014120085
- Peptide Label: isoform X5
- UniProtKB: A0A8I3NF63 (UniProtKB/TrEMBL),   A0A8P0SB97 (UniProtKB/TrEMBL),   A0A8P0ST64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022259731   ⟸   XM_022404023
- Peptide Label: isoform X6
- UniProtKB: A0A8C0JPQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038353491   ⟸   XM_038497563
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038353492   ⟸   XM_038497564
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038479986   ⟸   XM_038624058
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038479987   ⟸   XM_038624059
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038545736   ⟸   XM_038689808
- Peptide Label: isoform X1
- UniProtKB: A0A8I3NF63 (UniProtKB/TrEMBL),   A0A8P0SB97 (UniProtKB/TrEMBL),   A0A8P0ST64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038545737   ⟸   XM_038689809
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JPQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415941   ⟸   XM_038560013
- Peptide Label: isoform X3
- UniProtKB: A0A8I3NF63 (UniProtKB/TrEMBL),   A0A8P0SB97 (UniProtKB/TrEMBL),   A0A8P0ST64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415942   ⟸   XM_038560014
- Peptide Label: isoform X4
- UniProtKB: A0A8C0JPQ0 (UniProtKB/TrEMBL)
Protein Domains
Disintegrin   EGF-like   Peptidase M12B


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005818 UniProtKB/TrEMBL
  ENSCAFG00845010457 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000009388.5 UniProtKB/TrEMBL
  ENSCAFT00000049163.4 UniProtKB/TrEMBL
  ENSCAFT00845018429 ENTREZGENE
  ENSCAFT00845018429.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  Disintegrin_dom UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/TrEMBL
KEGG Report cfa:607729 UniProtKB/TrEMBL
NCBI Gene LOC607729 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPEPTIDASE DOMAIN 3 UniProtKB/TrEMBL
  ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN UniProtKB/TrEMBL
Pfam ADAM_CR UniProtKB/TrEMBL
  Disintegrin UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  DISIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF57552 UniProtKB/TrEMBL
UniProt A0A8C0JPQ0 ENTREZGENE
  A0A8I3NF63 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SB97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0ST64 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC607729  A disintegrin and metallopeptidase domain 3-like  LOC607729  disintegrin and metalloproteinase domain-containing protein 18-like  Symbol and/or name change 5135510 APPROVED