RTN4R (reticulon 4 receptor) - Rat Genome Database

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Gene: RTN4R (reticulon 4 receptor) Canis lupus familiaris
Analyze
Symbol: RTN4R
Name: reticulon 4 receptor
RGD ID: 12312456
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN axonogenesis (ortholog); cell surface receptor signaling pathway (ortholog); regulation of postsynapse assembly (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); FOUND IN glutamatergic synapse (ortholog); membrane raft (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: reticulon-4 receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,109,991 - 29,117,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,113,428 - 29,115,918 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,049,600 - 29,074,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,493,710 - 30,518,771 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,493,543 - 30,518,786 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,542,789 - 28,567,865 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,168,179 - 28,193,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,252,843 - 29,277,947 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RTN4R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,109,991 - 29,117,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,113,428 - 29,115,918 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,049,600 - 29,074,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,493,710 - 30,518,771 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,493,543 - 30,518,786 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,542,789 - 28,567,865 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,168,179 - 28,193,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,252,843 - 29,277,947 (+)NCBIUU_Cfam_GSD_1.0
RTN4R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,241,415 - 20,268,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,241,415 - 20,283,246 (-)EnsemblGRCh38hg38GRCh38
GRCh372220,228,938 - 20,255,841 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,608,938 - 18,635,816 (-)NCBINCBI36Build 36hg18NCBI36
Celera224,079,624 - 4,107,575 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,848,286 - 3,849,983 (-)NCBIHuRef
CHM1_12220,228,468 - 20,255,665 (-)NCBICHM1_1
T2T-CHM13v2.02220,621,207 - 20,649,434 (-)NCBIT2T-CHM13v2.0
Rtn4r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,945,506 - 17,970,272 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,945,506 - 17,970,272 (+)EnsemblGRCm39 Ensembl
GRCm381618,127,642 - 18,152,408 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,127,642 - 18,152,408 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,127,799 - 18,152,501 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,041,269 - 18,065,971 (+)NCBIMGSCv36mm8
Celera1618,700,292 - 18,725,154 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.23NCBI
Rtn4r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,348,613 - 96,373,554 (-)NCBIGRCr8
mRatBN7.21182,844,309 - 82,869,251 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,844,309 - 82,869,466 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,572,958 - 91,597,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,234,074 - 84,258,552 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,287,699 - 83,312,175 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,992,665 - 87,017,091 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,992,399 - 87,017,115 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,085,449 - 90,109,875 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,839,082 - 84,863,508 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11184,879,678 - 84,904,105 (-)NCBI
Celera1181,620,565 - 81,644,966 (-)NCBICelera
Cytogenetic Map11q23NCBI
Rtn4r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,866,398 - 17,891,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,866,508 - 17,891,803 (+)NCBIChiLan1.0ChiLan1.0
RTN4R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,870,208 - 29,899,082 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,417,166 - 32,446,008 (-)NCBINHGRI_mPanPan1
PanPan1.12218,673,548 - 18,675,537 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2218,673,548 - 18,680,017 (-)Ensemblpanpan1.1panPan2
Rtn4r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118138,598,174 - 138,623,308 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366194,130,748 - 4,155,894 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366194,130,757 - 4,155,885 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RTN4R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,579,046 - 51,602,968 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,579,043 - 51,603,180 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21455,216,090 - 55,240,021 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RTN4R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,469,854 - 5,497,858 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660851,437,876 - 1,466,276 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rtn4r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747829,850 - 855,991 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747829,947 - 855,942 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RTN4R
100 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000071620   ⟹   ENSCAFP00000064584
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2629,113,428 - 29,115,918 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845047165   ⟹   ENSCAFP00845037012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2630,493,543 - 30,518,786 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845047185   ⟹   ENSCAFP00845037031
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2630,496,214 - 30,518,786 (+)Ensembl
RefSeq Acc Id: XM_038437478   ⟹   XP_038293406
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02630,494,825 - 30,518,771 (+)NCBI
RefSeq Acc Id: XM_038437479   ⟹   XP_038293407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02630,493,710 - 30,518,771 (+)NCBI
RefSeq Acc Id: XM_038459305   ⟹   XP_038315233
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2629,050,965 - 29,074,655 (+)NCBI
RefSeq Acc Id: XM_038459306   ⟹   XP_038315234
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2629,049,600 - 29,074,655 (+)NCBI
RefSeq Acc Id: XM_038512351   ⟹   XP_038368279
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12628,543,900 - 28,567,865 (+)NCBI
RefSeq Acc Id: XM_038512352   ⟹   XP_038368280
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12628,542,789 - 28,567,865 (+)NCBI
RefSeq Acc Id: XM_038575856   ⟹   XP_038431784
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02629,253,954 - 29,277,947 (+)NCBI
RefSeq Acc Id: XM_038575857   ⟹   XP_038431785
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02629,252,843 - 29,277,947 (+)NCBI
RefSeq Acc Id: XM_038640066   ⟹   XP_038495994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02628,168,179 - 28,193,248 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000064584   ⟸   ENSCAFT00000071620
RefSeq Acc Id: XP_038368280   ⟸   XM_038512352
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038368279   ⟸   XM_038512351
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038495994   ⟸   XM_038640066
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038293407   ⟸   XM_038437479
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NYT2 (UniProtKB/TrEMBL),   A0A8I3SAC5 (UniProtKB/TrEMBL),   A0A8C0K396 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038293406   ⟸   XM_038437478
- Peptide Label: isoform X1
- UniProtKB: A0A8I3PX36 (UniProtKB/TrEMBL),   A0A8P0PDE2 (UniProtKB/TrEMBL),   A0A8C0K396 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315234   ⟸   XM_038459306
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NYT2 (UniProtKB/TrEMBL),   A0A8I3SAC5 (UniProtKB/TrEMBL),   A0A8C0K396 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315233   ⟸   XM_038459305
- Peptide Label: isoform X1
- UniProtKB: A0A8I3PX36 (UniProtKB/TrEMBL),   A0A8P0PDE2 (UniProtKB/TrEMBL),   A0A8C0K396 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431785   ⟸   XM_038575857
- Peptide Label: isoform X2
- UniProtKB: A0A8C0K396 (UniProtKB/TrEMBL),   A0A8C0NYT2 (UniProtKB/TrEMBL),   A0A8I3SAC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431784   ⟸   XM_038575856
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K396 (UniProtKB/TrEMBL),   A0A8I3PX36 (UniProtKB/TrEMBL),   A0A8P0PDE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845037031   ⟸   ENSCAFT00845047185
RefSeq Acc Id: ENSCAFP00845037012   ⟸   ENSCAFT00845047165
Protein Domains
LRRCT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000045006 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018166 UniProtKB/TrEMBL
  ENSCAFG00040020940 UniProtKB/TrEMBL
  ENSCAFG00845026751 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000071620.2 UniProtKB/TrEMBL
  ENSCAFT00000097070.1 UniProtKB/TrEMBL
  ENSCAFT00030033462.1 UniProtKB/TrEMBL
  ENSCAFT00040038807.1 UniProtKB/TrEMBL
  ENSCAFT00845047165 ENTREZGENE
  ENSCAFT00845047165.1 UniProtKB/TrEMBL
  ENSCAFT00845047185 ENTREZGENE
  ENSCAFT00845047185.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene RTN4R ENTREZGENE
PANTHER ANTIGEN BSP, PUTATIVE-RELATED UniProtKB/TrEMBL
  RETICULON-4 RECEPTOR UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A8C0K396 ENTREZGENE
  A0A8C0NYT2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PX36 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3SAC5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PDE2 ENTREZGENE, UniProtKB/TrEMBL