IPO11 (importin 11) - Rat Genome Database

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Gene: IPO11 (importin 11) Canis lupus familiaris
Analyze
Symbol: IPO11
Name: importin 11
RGD ID: 12308081
Description: ENCODES a protein that exhibits nuclear import signal receptor activity (inferred); small GTPase binding (inferred); INVOLVED IN ribosomal protein import into nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); hydrocephalus (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: importin-11
RGD Orthologs
Human
Mouse
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,737,525 - 48,938,199 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,761,796 - 48,937,124 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha245,748,467 - 45,948,863 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0249,215,561 - 49,416,604 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl249,215,587 - 49,416,594 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,284,305 - 46,486,261 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0247,071,163 - 47,272,148 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0247,927,714 - 48,128,709 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IPO11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,737,525 - 48,938,199 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,761,796 - 48,937,124 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha245,748,467 - 45,948,863 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0249,215,561 - 49,416,604 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl249,215,587 - 49,416,594 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,284,305 - 46,486,261 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0247,071,163 - 47,272,148 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0247,927,714 - 48,128,709 (+)NCBIUU_Cfam_GSD_1.0
IPO11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38562,412,763 - 62,628,582 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl562,403,972 - 62,628,582 (+)EnsemblGRCh38hg38GRCh38
GRCh37561,708,590 - 61,924,409 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map5q12.1NCBI
HuRef558,664,868 - 58,880,547 (+)NCBIHuRef
CHM1_1561,708,237 - 61,924,070 (+)NCBICHM1_1
T2T-CHM13v2.0563,232,336 - 63,448,295 (+)NCBIT2T-CHM13v2.0
Ipo11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913106,930,947 - 107,073,466 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13106,930,947 - 107,073,466 (-)EnsemblGRCm39 Ensembl
GRCm3813106,794,439 - 106,936,958 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13106,794,439 - 106,936,958 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713107,584,519 - 107,726,995 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613107,914,824 - 108,057,300 (-)NCBIMGSCv36mm8
Celera13111,130,272 - 111,272,792 (-)NCBICelera
Cytogenetic Map13D1- D2.1NCBI
cM Map1358.06NCBI
IPO11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1641,121,144 - 41,522,669 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11641,121,123 - 41,335,373 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21644,242,113 - 44,284,824 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in IPO11
1686 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 19 6 6 6 6 9 3 10 5
Low 3 5 3 6 3 5 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005617430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_535251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002619162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005322005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005355599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005390169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005423196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000011614   ⟹   ENSCAFP00000010763
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl248,761,796 - 48,937,124 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000079788   ⟹   ENSCAFP00000046802
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl248,761,796 - 48,937,124 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000089455   ⟹   ENSCAFP00000047126
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl248,762,656 - 48,937,124 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000089664   ⟹   ENSCAFP00000049997
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl248,761,796 - 48,910,868 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845015598   ⟹   ENSCAFP00845012122
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl249,215,587 - 49,416,594 (+)Ensembl
RefSeq Acc Id: XM_005617430   ⟹   XP_005617487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1248,737,525 - 48,884,460 (+)NCBI
Dog10K_Boxer_Tasha245,748,467 - 45,895,367 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038469894   ⟹   XP_038325822
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1246,284,306 - 46,486,261 (+)NCBI
RefSeq Acc Id: XM_038469895   ⟹   XP_038325823
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1246,284,305 - 46,432,528 (+)NCBI
RefSeq Acc Id: XM_038530703   ⟹   XP_038386631
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0247,927,715 - 48,128,709 (+)NCBI
RefSeq Acc Id: XM_038530704   ⟹   XP_038386632
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0247,927,714 - 48,075,196 (+)NCBI
RefSeq Acc Id: XM_038594928   ⟹   XP_038450856
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0247,071,164 - 47,272,148 (+)NCBI
RefSeq Acc Id: XM_038594929   ⟹   XP_038450857
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0247,071,163 - 47,218,472 (+)NCBI
RefSeq Acc Id: XM_038658999   ⟹   XP_038514927
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0249,215,562 - 49,416,604 (+)NCBI
RefSeq Acc Id: XM_038659000   ⟹   XP_038514928
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0249,215,561 - 49,363,078 (+)NCBI
RefSeq Acc Id: XM_535251   ⟹   XP_535251
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1248,737,526 - 48,938,199 (+)NCBI
Dog10K_Boxer_Tasha245,748,468 - 45,948,863 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002619162
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1248,737,525 - 48,936,910 (+)NCBI
Dog10K_Boxer_Tasha245,748,467 - 45,947,569 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005322005
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1246,284,305 - 46,484,967 (+)NCBI
RefSeq Acc Id: XR_005355599
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0247,927,714 - 48,127,414 (+)NCBI
RefSeq Acc Id: XR_005390169
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0247,071,163 - 47,270,854 (+)NCBI
RefSeq Acc Id: XR_005423196
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0249,215,561 - 49,415,309 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_535251   ⟸   XM_535251
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q0V4 (UniProtKB/TrEMBL),   A0A8I3N9P4 (UniProtKB/TrEMBL),   A0A8P0T2P0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005617487   ⟸   XM_005617430
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q6X7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000010763   ⟸   ENSCAFT00000011614
RefSeq Acc Id: ENSCAFP00000046802   ⟸   ENSCAFT00000079788
RefSeq Acc Id: ENSCAFP00000049997   ⟸   ENSCAFT00000089664
RefSeq Acc Id: ENSCAFP00000047126   ⟸   ENSCAFT00000089455
RefSeq Acc Id: XP_038325823   ⟸   XM_038469895
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325822   ⟸   XM_038469894
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038450857   ⟸   XM_038594929
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450856   ⟸   XM_038594928
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038514928   ⟸   XM_038659000
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q6X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514927   ⟸   XM_038658999
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q0V4 (UniProtKB/TrEMBL),   A0A8I3N9P4 (UniProtKB/TrEMBL),   A0A8P0T2P0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386632   ⟸   XM_038530704
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q6X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386631   ⟸   XM_038530703
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q0V4 (UniProtKB/TrEMBL),   A0A8I3N9P4 (UniProtKB/TrEMBL),   A0A8P0T2P0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845012122   ⟸   ENSCAFT00845015598
Protein Domains
Importin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007240 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001890 UniProtKB/TrEMBL
  ENSCAFG00040002457 UniProtKB/TrEMBL
  ENSCAFG00845008856 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000089664.2 UniProtKB/TrEMBL
  ENSCAFT00030003553.1 UniProtKB/TrEMBL
  ENSCAFT00030003636.1 UniProtKB/TrEMBL
  ENSCAFT00030003674.1 UniProtKB/TrEMBL
  ENSCAFT00040004860.1 UniProtKB/TrEMBL
  ENSCAFT00040004904.1 UniProtKB/TrEMBL
  ENSCAFT00040004989.1 UniProtKB/TrEMBL
  ENSCAFT00845015598 ENTREZGENE
  ENSCAFT00845015598.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
NCBI Gene IPO11 ENTREZGENE
PANTHER IMPORTIN-11 UniProtKB/TrEMBL
  IMPORTIN-7, 8, 11 UniProtKB/TrEMBL
Pfam IBN_N UniProtKB/TrEMBL
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C0PUF9_CANLF UniProtKB/TrEMBL
  A0A8C0Q0V4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q6X7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N9P4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0T2P0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49760 ENTREZGENE