UCK1 (uridine-cytidine kinase 1) - Rat Genome Database

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Gene: UCK1 (uridine-cytidine kinase 1) Canis lupus familiaris
Analyze
Symbol: UCK1
Name: uridine-cytidine kinase 1
RGD ID: 12288795
Description: ENCODES a protein that exhibits ATP binding (inferred); cytidine kinase activity (inferred); kinase activity (inferred); INVOLVED IN UMP biosynthetic process (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy (ortholog); Ehlers-Danlos syndrome classic type 1 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1952,609,972 - 52,615,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl952,609,313 - 52,614,622 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha951,878,198 - 51,883,925 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0953,513,447 - 53,519,165 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl953,513,484 - 53,519,162 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1952,291,329 - 52,297,027 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0952,610,265 - 52,615,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0952,704,647 - 52,710,374 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UCK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1952,609,972 - 52,615,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl952,609,313 - 52,614,622 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha951,878,198 - 51,883,925 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0953,513,447 - 53,519,165 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl953,513,484 - 53,519,162 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1952,291,329 - 52,297,027 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0952,610,265 - 52,615,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0952,704,647 - 52,710,374 (+)NCBIUU_Cfam_GSD_1.0
UCK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389131,523,801 - 131,531,263 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9131,523,801 - 131,531,264 (-)EnsemblGRCh38hg38GRCh38
GRCh379134,399,188 - 134,406,650 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369133,389,012 - 133,396,476 (-)NCBINCBI36Build 36hg18NCBI36
Build 349131,428,744 - 131,436,209NCBI
Celera9104,939,363 - 104,946,841 (-)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9103,893,800 - 103,901,279 (-)NCBIHuRef
CHM1_19134,548,581 - 134,556,053 (-)NCBICHM1_1
T2T-CHM13v2.09143,736,763 - 143,744,224 (-)NCBIT2T-CHM13v2.0
Uck1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,145,014 - 32,150,117 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,145,014 - 32,150,171 (-)EnsemblGRCm39 Ensembl
GRCm38232,255,002 - 32,260,105 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,255,002 - 32,260,159 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,110,522 - 32,115,625 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,077,011 - 32,082,070 (-)NCBIMGSCv36mm8
Celera231,959,332 - 31,964,435 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Uck1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8335,936,328 - 35,942,213 (-)NCBIGRCr8
mRatBN7.2315,538,580 - 15,544,465 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,538,591 - 15,544,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,607,992 - 18,613,850 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,192,985 - 27,198,843 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,443,461 - 25,449,354 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,271,874 - 11,277,757 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,271,885 - 11,277,757 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,620,744 - 16,626,627 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,366,634 - 11,372,517 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,264,015 - 11,268,800 (-)NCBI
Celera310,283,446 - 10,289,273 (-)NCBICelera
Cytogenetic Map3p12NCBI
Uck1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555131,203,934 - 1,208,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555131,203,934 - 1,208,720 (-)NCBIChiLan1.0ChiLan1.0
UCK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2117,823,442 - 7,830,941 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan197,825,808 - 7,832,527 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09102,646,056 - 102,653,525 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19131,285,877 - 131,293,338 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9131,285,877 - 131,293,338 (-)Ensemblpanpan1.1panPan2
Uck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947198,499,351 - 198,502,882 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648718,267,885 - 18,271,423 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648718,267,878 - 18,271,406 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1271,448,365 - 271,453,816 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11271,448,362 - 271,453,811 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21305,456,743 - 305,462,182 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UCK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1126,612,306 - 6,634,326 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl126,612,378 - 6,618,968 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660798,922,082 - 8,946,096 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uck1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247604,490,086 - 4,494,924 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247604,490,118 - 4,494,707 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UCK1
93 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 18 2 6 2 6 6 12 8 10 6
Low 4 4 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022423937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000031666   ⟹   ENSCAFP00000029480
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl952,609,928 - 52,614,622 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000078011   ⟹   ENSCAFP00000045401
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl952,609,313 - 52,612,461 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845033198   ⟹   ENSCAFP00845025989
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl953,513,484 - 53,519,162 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845033246   ⟹   ENSCAFP00845026029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl953,513,484 - 53,519,162 (+)Ensembl
RefSeq Acc Id: XM_038487108   ⟹   XP_038343036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1952,291,329 - 52,297,027 (+)NCBI
RefSeq Acc Id: XM_038548985   ⟹   XP_038404913
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0952,704,647 - 52,710,374 (+)NCBI
RefSeq Acc Id: XM_038548986   ⟹   XP_038404914
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0952,704,647 - 52,710,374 (+)NCBI
RefSeq Acc Id: XM_038548987   ⟹   XP_038404915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0952,704,647 - 52,710,374 (+)NCBI
RefSeq Acc Id: XM_038612936   ⟹   XP_038468864
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0952,610,265 - 52,615,976 (+)NCBI
RefSeq Acc Id: XM_038612937   ⟹   XP_038468865
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0952,610,265 - 52,615,976 (+)NCBI
RefSeq Acc Id: XM_038612938   ⟹   XP_038468866
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0952,610,265 - 52,615,976 (+)NCBI
RefSeq Acc Id: XM_038616804   ⟹   XP_038472732
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha951,878,198 - 51,883,925 (+)NCBI
RefSeq Acc Id: XM_038616811   ⟹   XP_038472739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha951,878,198 - 51,883,925 (+)NCBI
RefSeq Acc Id: XM_038616820   ⟹   XP_038472748
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha951,878,198 - 51,883,925 (+)NCBI
RefSeq Acc Id: XM_038678243   ⟹   XP_038534171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0953,513,447 - 53,519,165 (+)NCBI
RefSeq Acc Id: XM_038678244   ⟹   XP_038534172
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0953,513,447 - 53,519,165 (+)NCBI
RefSeq Acc Id: XM_038678245   ⟹   XP_038534173
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0953,513,447 - 53,519,165 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000045401   ⟸   ENSCAFT00000078011
RefSeq Acc Id: ENSCAFP00000029480   ⟸   ENSCAFT00000031666
RefSeq Acc Id: XP_038343036   ⟸   XM_038487108
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038468864   ⟸   XM_038612936
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468865   ⟸   XM_038612937
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038468866   ⟸   XM_038612938
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038534171   ⟸   XM_038678243
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PYY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534172   ⟸   XM_038678244
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LNT3 (UniProtKB/TrEMBL),   A0A8C0NE43 (UniProtKB/TrEMBL),   A0A8I3P1H2 (UniProtKB/TrEMBL),   A0A8C0PYY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534173   ⟸   XM_038678245
- Peptide Label: isoform X3
- UniProtKB: A0A8I3PF59 (UniProtKB/TrEMBL),   A0A8C0RX62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038472732   ⟸   XM_038616804
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PYY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038472739   ⟸   XM_038616811
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LNT3 (UniProtKB/TrEMBL),   A0A8C0NE43 (UniProtKB/TrEMBL),   A0A8I3P1H2 (UniProtKB/TrEMBL),   A0A8C0PYY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038472748   ⟸   XM_038616820
- Peptide Label: isoform X3
- UniProtKB: A0A8P0NVM8 (UniProtKB/TrEMBL),   A0A8C0RX62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404913   ⟸   XM_038548985
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PYY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404914   ⟸   XM_038548986
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LNT3 (UniProtKB/TrEMBL),   A0A8C0NE43 (UniProtKB/TrEMBL),   A0A8C0PYY6 (UniProtKB/TrEMBL),   A0A8I3P1H2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404915   ⟸   XM_038548987
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RX62 (UniProtKB/TrEMBL),   A0A8P0NVM8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845026029   ⟸   ENSCAFT00845033246
RefSeq Acc Id: ENSCAFP00845025989   ⟸   ENSCAFT00845033198
Protein Domains
Phosphoribulokinase/uridine kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019903 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015828 UniProtKB/TrEMBL
  ENSCAFG00040003788 UniProtKB/TrEMBL
  ENSCAFG00845018761 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031666.5 UniProtKB/TrEMBL
  ENSCAFT00000078011.2 UniProtKB/TrEMBL
  ENSCAFT00030029159.1 UniProtKB/TrEMBL
  ENSCAFT00030029245.1 UniProtKB/TrEMBL
  ENSCAFT00030029298.1 UniProtKB/TrEMBL
  ENSCAFT00040007250.1 UniProtKB/TrEMBL
  ENSCAFT00040007266.1 UniProtKB/TrEMBL
  ENSCAFT00845033198 ENTREZGENE
  ENSCAFT00845033198.1 UniProtKB/TrEMBL
  ENSCAFT00845033246 ENTREZGENE
  ENSCAFT00845033246.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  PRK/URK UniProtKB/TrEMBL
  Uridine_kinase-like UniProtKB/TrEMBL
NCBI Gene UCK1 ENTREZGENE
PANTHER PTHR10285:SF66 UniProtKB/TrEMBL
  URIDINE KINASE UniProtKB/TrEMBL
Pfam PRK UniProtKB/TrEMBL
PRINTS URIDINKINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0LNT3 ENTREZGENE
  A0A8C0NE43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NED4_CANLF UniProtKB/TrEMBL
  A0A8C0NU99_CANLF UniProtKB/TrEMBL
  A0A8C0PYY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RX62 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P1H2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PF59 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NVM8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:58343 ENTREZGENE