TSC1 (TSC complex subunit 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TSC1 (TSC complex subunit 1) Canis lupus familiaris
Analyze
Symbol: TSC1
Name: TSC complex subunit 1
RGD ID: 12288464
Description: ENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN adaptive immune response (ortholog); adult locomotory behavior (ortholog); cardiac muscle cell differentiation (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; mTOR signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); anterior segment dysgenesis (ortholog); autism spectrum disorder (ortholog); FOUND IN cell projection (ortholog); growth cone (ortholog); lysosomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromosome 9 TSC1; hamartin; tuberous sclerosis 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,409,307 - 51,459,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,425,937 - 51,454,677 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,673,940 - 50,724,548 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,304,134 - 52,354,724 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,304,753 - 52,354,693 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,082,516 - 51,133,112 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,407,015 - 51,457,594 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,486,514 - 51,537,117 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (IEA,ISO)
adult locomotory behavior  (ISO)
associative learning  (IEA)
cardiac muscle cell differentiation  (IEA,ISO)
cell population proliferation  (IEA,ISO)
cell projection organization  (IEA,ISO)
cell-matrix adhesion  (IEA)
cellular response to decreased oxygen levels  (ISO)
cellular response to starvation  (IEA)
cerebral cortex development  (IEA,ISO)
glucose import  (IEA,ISO)
hippocampus development  (IEA,ISO)
kidney development  (IEA,ISO)
memory T cell differentiation  (IEA,ISO)
myelination  (IEA,ISO)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of cell size  (IEA,ISO)
negative regulation of cellular response to oxidative stress  (ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of macroautophagy  (ISO)
negative regulation of neuron projection development  (ISO)
negative regulation of TOR signaling  (IEA)
negative regulation of TORC1 signaling  (IEA)
negative regulation of translation  (IEA)
nervous system development  (IEA,ISO)
neural tube closure  (IEA,ISO)
positive regulation of focal adhesion assembly  (IEA)
positive regulation of macroautophagy  (ISO)
positive regulation of stress fiber assembly  (ISO)
potassium ion transport  (IEA,ISO)
protein stabilization  (IEA)
regulation of cell cycle  (IEA)
regulation of cell-matrix adhesion  (IEA)
regulation of focal adhesion assembly  (ISO)
regulation of stress fiber assembly  (IEA)
regulation of translation  (IEA)
response to insulin  (IEA)
response to nutrient levels  (ISO)
response to peptide  (ISO)
ribosomal subunit export from nucleus  (IEA)
synapse organization  (IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:10759551   PMID:30032202  


Genomics

Comparative Map Data
TSC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,409,307 - 51,459,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,425,937 - 51,454,677 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,673,940 - 50,724,548 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,304,134 - 52,354,724 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,304,753 - 52,354,693 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,082,516 - 51,133,112 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,407,015 - 51,457,594 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,486,514 - 51,537,117 (+)NCBIUU_Cfam_GSD_1.0
TSC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389132,891,349 - 132,945,378 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9132,891,348 - 132,946,874 (-)EnsemblGRCh38hg38GRCh38
GRCh379135,766,736 - 135,820,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,756,557 - 134,809,841 (-)NCBINCBI36Build 36hg18NCBI36
Build 349132,815,940 - 132,849,574NCBI
Celera9106,308,473 - 106,361,761 (-)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,260,658 - 105,313,711 (-)NCBIHuRef
CHM1_19135,917,213 - 135,970,447 (-)NCBICHM1_1
T2T-CHM13v2.09145,103,162 - 145,157,190 (-)NCBIT2T-CHM13v2.0
Tsc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,531,005 - 28,581,183 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,531,240 - 28,581,179 (+)EnsemblGRCm39 Ensembl
GRCm38228,640,993 - 28,691,172 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,641,228 - 28,691,167 (+)EnsemblGRCm38mm10GRCm38
MGSCv37228,496,763 - 28,546,687 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,463,252 - 28,513,176 (+)NCBIMGSCv36mm8
Celera228,345,749 - 28,395,673 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Tsc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,367,434 - 32,416,565 (+)NCBIGRCr8
mRatBN7.2311,969,547 - 12,018,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,979,729 - 12,015,674 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,059,218 - 15,086,859 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,644,177 - 23,671,817 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,898,622 - 21,926,266 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,219,955 - 7,269,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,237,192 - 7,265,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,570,765 - 12,619,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,645,313 - 7,672,944 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,645,612 - 7,673,244 (+)NCBI
Celera36,767,562 - 6,795,193 (+)NCBICelera
Cytogenetic Map3p12NCBI
Tsc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,197,037 - 2,244,992 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,197,037 - 2,244,992 (-)NCBIChiLan1.0ChiLan1.0
TSC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,414,619 - 6,468,611 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,415,528 - 6,470,948 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,007,708 - 104,060,938 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,638,003 - 132,692,264 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,638,003 - 132,675,759 (-)Ensemblpanpan1.1panPan2
Tsc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,562,656 - 199,618,374 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,331,194 - 19,386,892 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648719,331,183 - 19,386,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,636,532 - 272,685,951 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,636,530 - 272,685,948 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,795,196 - 306,819,962 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TSC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1125,195,604 - 5,249,042 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,195,675 - 5,244,157 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,396,791 - 10,450,324 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tsc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,498,692 - 3,532,011 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,479,028 - 3,536,612 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TSC1
485 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 16 2 5 1 12 8 10 1
Low 5 5 6 6 4 6 1 5 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022423653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022423654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022423655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022423656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038487042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038548896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038612847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038616011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038678153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_537808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF201838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000031635   ⟹   ENSCAFP00000029451
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl951,425,937 - 51,454,677 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000037901   ⟹   ENSCAFP00000033542
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl951,425,937 - 51,454,677 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000072310   ⟹   ENSCAFP00000045098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl951,425,937 - 51,442,338 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028629   ⟹   ENSCAFP00845022532
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl952,304,753 - 52,337,521 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028657   ⟹   ENSCAFP00845022553
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl952,304,753 - 52,336,964 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028734   ⟹   ENSCAFP00845022615
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl952,304,757 - 52,354,693 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028795   ⟹   ENSCAFP00845022661
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl952,304,757 - 52,354,693 (+)Ensembl
RefSeq Acc Id: XM_022423653   ⟹   XP_022279361
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1951,409,307 - 51,459,546 (+)NCBI
Dog10K_Boxer_Tasha950,674,549 - 50,724,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022423654   ⟹   XP_022279362
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1951,409,354 - 51,459,546 (+)NCBI
Dog10K_Boxer_Tasha950,674,593 - 50,724,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022423655   ⟹   XP_022279363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1951,410,442 - 51,459,546 (+)NCBI
Dog10K_Boxer_Tasha950,675,456 - 50,724,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022423656   ⟹   XP_022279364
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1951,409,317 - 51,459,546 (+)NCBI
Dog10K_Boxer_Tasha950,674,529 - 50,724,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038487035   ⟹   XP_038342963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,083,083 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038487036   ⟹   XP_038342964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,083,102 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038487037   ⟹   XP_038342965
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,083,146 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038487039   ⟹   XP_038342967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,084,011 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038487040   ⟹   XP_038342968
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,082,516 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038487041   ⟹   XP_038342969
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,083,083 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038487042   ⟹   XP_038342970
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1951,083,082 - 51,133,112 (+)NCBI
RefSeq Acc Id: XM_038548889   ⟹   XP_038404817
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,487,104 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038548890   ⟹   XP_038404818
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,487,123 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038548892   ⟹   XP_038404820
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,487,167 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038548893   ⟹   XP_038404821
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,488,016 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038548894   ⟹   XP_038404822
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,486,514 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038548895   ⟹   XP_038404823
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,487,104 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038548896   ⟹   XP_038404824
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0951,487,103 - 51,537,117 (+)NCBI
RefSeq Acc Id: XM_038612841   ⟹   XP_038468769
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,407,582 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038612842   ⟹   XP_038468770
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,407,601 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038612843   ⟹   XP_038468771
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,407,645 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038612844   ⟹   XP_038468772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,408,497 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038612845   ⟹   XP_038468773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,407,015 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038612846   ⟹   XP_038468774
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,407,582 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038612847   ⟹   XP_038468775
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0951,407,581 - 51,457,594 (+)NCBI
RefSeq Acc Id: XM_038616004   ⟹   XP_038471932
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha950,673,940 - 50,724,548 (+)NCBI
RefSeq Acc Id: XM_038616011   ⟹   XP_038471939
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha950,674,530 - 50,724,548 (+)NCBI
RefSeq Acc Id: XM_038678146   ⟹   XP_038534074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,304,701 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_038678147   ⟹   XP_038534075
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,304,720 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_038678148   ⟹   XP_038534076
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,304,764 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_038678149   ⟹   XP_038534077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,305,629 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_038678151   ⟹   XP_038534079
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,304,134 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_038678152   ⟹   XP_038534080
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,304,701 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_038678153   ⟹   XP_038534081
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0952,304,700 - 52,354,724 (+)NCBI
RefSeq Acc Id: XM_537808   ⟹   XP_537808
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1951,409,317 - 51,459,546 (+)NCBI
Dog10K_Boxer_Tasha950,674,530 - 50,724,548 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_022279361 (Get FASTA)   NCBI Sequence Viewer  
  XP_022279362 (Get FASTA)   NCBI Sequence Viewer  
  XP_022279363 (Get FASTA)   NCBI Sequence Viewer  
  XP_022279364 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342963 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342964 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342965 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342967 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342968 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342969 (Get FASTA)   NCBI Sequence Viewer  
  XP_038342970 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404817 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404818 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404820 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404821 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404822 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404823 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404824 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468769 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468770 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468771 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468772 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468773 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468774 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468775 (Get FASTA)   NCBI Sequence Viewer  
  XP_038471932 (Get FASTA)   NCBI Sequence Viewer  
  XP_038471939 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534074 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534075 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534076 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534077 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534079 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534080 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534081 (Get FASTA)   NCBI Sequence Viewer  
  XP_537808 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000029451.4
  ENSCAFP00000033542.3
  ENSCAFP00000045098.1
  ENSCAFP00000072943.1
  ENSCAFP00030030253.1
  ENSCAFP00030030444.1
  ENSCAFP00030030493.1
  ENSCAFP00040004747.1
  ENSCAFP00040004759.1
  ENSCAFP00040004773.1
  ENSCAFP00845022532.1
  ENSCAFP00845022553.1
  ENSCAFP00845022615
  ENSCAFP00845022615.1
  ENSCAFP00845022661.1
Reference Protein Sequences
RefSeq Acc Id: XP_537808   ⟸   XM_537808
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022279361   ⟸   XM_022423653
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022279364   ⟸   XM_022423656
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022279362   ⟸   XM_022423654
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022279363   ⟸   XM_022423655
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000033542   ⟸   ENSCAFT00000037901
RefSeq Acc Id: ENSCAFP00000045098   ⟸   ENSCAFT00000072310
RefSeq Acc Id: ENSCAFP00000029451   ⟸   ENSCAFT00000031635
RefSeq Acc Id: XP_038342968   ⟸   XM_038487040
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038342970   ⟸   XM_038487042
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038342969   ⟸   XM_038487041
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038342963   ⟸   XM_038487035
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038342964   ⟸   XM_038487036
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038342965   ⟸   XM_038487037
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038342967   ⟸   XM_038487039
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468773   ⟸   XM_038612845
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468775   ⟸   XM_038612847
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038468774   ⟸   XM_038612846
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468769   ⟸   XM_038612841
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468770   ⟸   XM_038612842
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468771   ⟸   XM_038612843
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038468772   ⟸   XM_038612844
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038534079   ⟸   XM_038678151
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534081   ⟸   XM_038678153
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534080   ⟸   XM_038678152
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534074   ⟸   XM_038678146
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534075   ⟸   XM_038678147
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534076   ⟸   XM_038678148
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038534077   ⟸   XM_038678149
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038471932   ⟸   XM_038616004
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038471939   ⟸   XM_038616011
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404822   ⟸   XM_038548894
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404824   ⟸   XM_038548896
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404823   ⟸   XM_038548895
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404817   ⟸   XM_038548889
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404818   ⟸   XM_038548890
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404820   ⟸   XM_038548892
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404821   ⟸   XM_038548893
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LLW0 (UniProtKB/TrEMBL),   A0A8C0NVV6 (UniProtKB/TrEMBL),   A0A8C0Q0D8 (UniProtKB/TrEMBL),   A0A8I3P1V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845022615   ⟸   ENSCAFT00845028734
RefSeq Acc Id: ENSCAFP00845022661   ⟸   ENSCAFT00845028795
RefSeq Acc Id: ENSCAFP00845022553   ⟸   ENSCAFT00845028657
RefSeq Acc Id: ENSCAFP00845022532   ⟸   ENSCAFT00845028629


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019882 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018760 UniProtKB/TrEMBL
  ENSCAFG00040002894 UniProtKB/TrEMBL
  ENSCAFG00845016069 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031635.6 UniProtKB/TrEMBL
  ENSCAFT00000037901.4 UniProtKB/TrEMBL
  ENSCAFT00000072310.2 UniProtKB/TrEMBL
  ENSCAFT00000094092.1 UniProtKB/TrEMBL
  ENSCAFT00030034688.1 UniProtKB/TrEMBL
  ENSCAFT00030034916.1 UniProtKB/TrEMBL
  ENSCAFT00030034967.1 UniProtKB/TrEMBL
  ENSCAFT00040005522.1 UniProtKB/TrEMBL
  ENSCAFT00040005535.1 UniProtKB/TrEMBL
  ENSCAFT00040005549.1 UniProtKB/TrEMBL
  ENSCAFT00845028629.1 UniProtKB/TrEMBL
  ENSCAFT00845028657.1 UniProtKB/TrEMBL
  ENSCAFT00845028734 ENTREZGENE
  ENSCAFT00845028734.1 UniProtKB/TrEMBL
  ENSCAFT00845028795.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Hamartin UniProtKB/TrEMBL
NCBI Gene TSC1 ENTREZGENE
PANTHER HAMARTIN UniProtKB/TrEMBL
  PTHR15154 UniProtKB/TrEMBL
Pfam Hamartin UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C0LLW0 ENTREZGENE
  A0A8C0NR06_CANLF UniProtKB/TrEMBL
  A0A8C0NVV6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q0D8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q0F0_CANLF UniProtKB/TrEMBL
  A0A8I3NUE2_CANLF UniProtKB/TrEMBL
  A0A8I3NYL5_CANLF UniProtKB/TrEMBL
  A0A8I3NZ75_CANLF UniProtKB/TrEMBL
  A0A8I3P1V6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PPF7_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:47890 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-04 TSC1  TSC complex subunit 1    tuberous sclerosis 1  Symbol and/or name change 5135510 APPROVED