GMPR (guanosine monophosphate reductase)

Gene: GMPR (guanosine monophosphate reductase) Canis lupus familiaris

Analyze

Symbol:

GMPR

Name:

guanosine monophosphate reductase

RGD ID:

12278919

Description:

ENCODES a protein that exhibits GMP reductase activity (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN nucleotide metabolic process (inferred); purine nucleobase metabolic process (inferred); purine nucleotide metabolic process (inferred); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); FOUND IN GMP reductase complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

GMP reductase 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	15,400,937 - 15,449,157 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	15,401,003 - 15,448,022 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	15,349,846 - 15,399,870 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	15,496,728 - 15,546,793 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	15,496,742 - 15,592,481 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	15,320,905 - 15,370,911 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	15,373,463 - 15,423,499 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	16,699,506 - 16,749,559 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

juvenile rheumatoid arthritis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nucleotide metabolic process (IEA)

purine nucleobase metabolic process (IEA)

purine nucleotide metabolic process (IEA)

Cellular Component

GMP reductase complex (IEA)

Molecular Function

GMP reductase activity (IEA)

metal ion binding (IEA)

oxidoreductase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

adenine phoshoribosyltransferase deficiency pathway (ISO)

adenosine monophosphate deaminase deficiency pathway (ISO)

adenylosuccinate lyase deficiency pathway (ISO)

AICA-ribosuria pathway (ISO)

azathioprine pharmacodynamics pathway (ISO)

Kelley-Seegmiller syndrome pathway (ISO)

Lesch-Nyhan syndrome pathway (ISO)

mercaptopurine pharmacodynamics pathway (ISO)

molybdenum cofactor deficiency pathway (ISO)

purine metabolic pathway (ISO)

purine nucleoside phosphorylase deficiency pathway (ISO)

tioguanine pharmacodynamics pathway (ISO)

xanthinuria type I pathway (ISO)

xanthinuria pathway (ISO)

xanthinuria type II pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

GMPR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	15,400,937 - 15,449,157 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	15,401,003 - 15,448,022 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	15,349,846 - 15,399,870 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	15,496,728 - 15,546,793 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	15,496,742 - 15,592,481 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	15,320,905 - 15,370,911 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	15,373,463 - 15,423,499 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	16,699,506 - 16,749,559 (+)	NCBI		UU_Cfam_GSD_1.0

GMPR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	16,238,587 - 16,295,549 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	16,238,587 - 16,295,549 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	16,238,818 - 16,295,780 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	16,346,790 - 16,403,759 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	16,346,789 - 16,403,757	NCBI
Celera	6	17,476,654 - 17,533,599 (+)	NCBI		Celera
Cytogenetic Map	6	p22.3	NCBI
HuRef	6	16,186,158 - 16,243,078 (+)	NCBI		HuRef
CHM1_1	6	16,241,507 - 16,298,432 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	16,111,201 - 16,168,104 (+)	NCBI		T2T-CHM13v2.0

Gmpr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	45,660,905 - 45,699,862 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	45,660,920 - 45,707,276 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	45,507,428 - 45,546,386 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	45,507,444 - 45,553,800 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	45,602,838 - 45,641,750 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	45,518,441 - 45,557,353 (+)	NCBI		MGSCv36	mm8
Celera	13	46,580,855 - 46,622,246 (+)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI
cM Map	13	21.94	NCBI

Gmpr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	19,357,992 - 19,395,807 (-)	NCBI		GRCr8
mRatBN7.2	17	19,151,820 - 19,189,626 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	19,151,815 - 19,189,621 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	19,036,980 - 19,073,481 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	20,640,806 - 20,677,305 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	18,964,099 - 19,000,597 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	19,543,274 - 19,580,929 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	19,543,275 - 19,580,929 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	21,568,731 - 21,606,386 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	25,147,730 - 25,185,385 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	25,150,571 - 25,188,226 (-)	NCBI
Celera	17	18,854,190 - 18,891,279 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

Gmpr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955483	9,559,079 - 9,608,953 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955483	9,559,079 - 9,608,807 (-)	NCBI	ChiLan1.0	ChiLan1.0

GMPR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	30,905,788 - 30,962,484 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	26,891,362 - 26,948,043 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	16,094,994 - 16,151,499 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	16,460,654 - 16,515,796 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	16,460,651 - 16,515,796 (+)	Ensembl	panpan1.1		panPan2

Gmpr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	9,234,796 - 9,272,152 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936552	2,458,698 - 2,497,191 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936552	2,458,728 - 2,496,145 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GMPR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	12,254,388 - 12,299,531 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	12,254,393 - 12,298,802 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	12,850,715 - 12,893,449 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GMPR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	55,843,576 - 55,893,334 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	55,840,978 - 55,893,361 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	16,329,567 - 16,378,381 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gmpr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624756	10,169,365 - 10,213,419 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624756	10,170,074 - 10,213,258 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GMPR
732 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5						6	5
Low			22	6	6	6	6		7	8	10	6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038446435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038520578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038584227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038648636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_545353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000015790 ⟹ ENSCAFP00000014617

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	35	15,401,003 - 15,448,022 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845042999 ⟹ ENSCAFP00845033713

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	35	15,496,742 - 15,592,481 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845043098 ⟹ ENSCAFP00845033787

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	35	15,496,751 - 15,546,793 (+)	Ensembl

RefSeq Acc Id:

XM_038446435 ⟹ XP_038302363

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	35	15,496,728 - 15,546,793 (+)	NCBI

RefSeq Acc Id:

XM_038520578 ⟹ XP_038376506

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	35	15,320,905 - 15,370,911 (+)	NCBI

RefSeq Acc Id:

XM_038584227 ⟹ XP_038440155

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	35	16,699,506 - 16,749,559 (+)	NCBI

RefSeq Acc Id:

XM_038648636 ⟹ XP_038504564

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	35	15,373,463 - 15,423,499 (+)	NCBI

RefSeq Acc Id:

XM_545353 ⟹ XP_545353

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	35	15,400,937 - 15,449,157 (+)	NCBI
Dog10K_Boxer_Tasha	35	15,349,846 - 15,399,870 (+)	NCBI

Sequence:

show sequence

CCAGCCCCCTCCGCCGCCCGGCGCCCGCGCTGCAGGAAGGAGGTGCCCGCTCTCAGCCGCGCCT
GCCCCAGCGCGCCGATCCGCACCATGCCCCGCATAGATGCCGACCTCAAGCTGGACTTTAAGGA
TGTCCTGCTCCGACCCAAGCGGAGCAGCCTCAGGAGCCGAGCCGAGGTGGACCTTGAGCGTACC
TTCACATTTCGAAACTCAAAGCAGACCTACTCAGGGATTCCCATCATTGTGGCCAACATGGACA
CCGTGGGGACATTTGAGATGGCAGTGGTGATGTCACAGCACTCCATGTTTACAGCAGTTCATAA
GCACTATACCCTGGATGACTGGAAGCTCTTTGCTGCTCATCACCCAGAATGTCTGCAGCACGTA
GCCGTGAGTTCGGGCAGTGGGAAGAGCGATCTGGAAAAGATGAGTGGCATCTTGGAAGCGGTGC
CGCAGGTCAAGTTTATTTGCCTGGATGTGGCCAACGGGTACTCAGAACATTTTGTGGAGTTCGT
GAAGCTGGTGCGTGCCAAATTTCCAGAACATACCATCATGGCAGGGAACGTGGTAACAGGGGAG
ATGGTGGAAGAGCTTATTCTTTCTGGAGCGGACATAATCAAAGTGGGTGTCGGACCAGGTTCCG
TGTGTACCACCCGCACCAAGACGGGGGTGGGCTACCCCCAGCTCAGTGCTGTGATCGAGTGTGC
GGACTCTGCCCACGGCCTGAAGGGTCACATCATCTCCGATGGAGGCTGCACGTGTCCAGGAGAT
GTCGCCAAAGCCTTTGGAGCTGGAGCAGATTTTGTCATGCTGGGCGGGATGTTTTCAGGCCACA
CCGAGTGTGCCGGGGAGGTGATCGAGAAGAATGGGCAGAAGCTCAAGCTCTTCTACGGGATGAG
CTCCGAAACAGCAATGAAGAAGCATGCAGGAGGGGTCGCTGAATACAGAGCGTCTGAGGGCAAG
ACTGTGGAAGTGCCTTACAAGGGGGATGTAGAAAACACTATTCTGGATATTCTTGGGGGACTGA
GGTCTACCTGCACTTATGTGGGGGCCGCCAAACTCAAAGAGCTCAGCAGGAGGGCAACGTTCAT
CCGGGTGACCCAACAGCACAACACGGTGTTCAGCTAACCTTGAGGATGAGGTGACGTCCAGCTC
GTGGAAGCTTCCACTCACACCTGCTTTCCCACCTCCCTCCTGTTACATCAGAGTTTCTGGCTGT
TCTGAGTGGTGGACGACTGCCTCCTGCTCCCCTACCCGCACCCTGGAGGCTCTGGGGCTCCCCT
CGTGCCTTCGGGGGGCCCAGAAGAGGGCCCTGACCCAGTCCGTGGTCAGAGCCCAGCTGCCTGG
AACTCATAACCTCATTGTTAAAACTAACTCACCTCTTTCTTTCTCTCTCTTTTTTTTTTTTTTT
AAAGAAAAATGGTTTCACTTTAATATAATGCAATTATCTTAAGACTTGGTGGAGTGCTGGAGTT
TGCATTTGCAGGAAACAAGTTGTCAGGGGTGCTGGGGGTTTTCTACCTTTTTCCCACGCTGGGC
TCTTAGCATTCAGGGCTGGGGTGTTGGAGGAGGAGAGGGCAGGGGAGGGTCGGGCTGGCCAGAG
TAACTGGCGTCCCCTCCTCCGCTTTTGGTTGCTAGCGAAGAACAAAAGCGCCTGACTAGACACA
TGAACTTGGAGGGGCCTCACTGCAGATACTCACAAGGTGTGGCGACCCGTTTCCAGGACCTGAG
TTACACATGCCTTTGGGGAGTAGACATCTGTCACTGTGAGGTCCAGGTTGCTCTGGGGACGCTG
TTCCTGTCCTGATTTTTCATCGACTTTTGTTGTGCTTCAGCTCTTTCCTCCTTGGTCCCAACCT
GTCGGGCTGGCTTCCCTCTTAAAGAGATGACACGTGATTTTGAAGTTCAGTAGGACTGAACCTA
TTCAATAGGATAACCTTTTATTGAGAGGTTGTCCATCAAAAAATTGGCGAGTGGCATCCTTACT
GAAAGACAGTAAAAACCTTGACCAGCGGCTTTCTAAAAGCCTTTGGTTTAAAAATACGAGAACT
ATTCCCTTGTCCAGGCCATTACTACTTTGGAGGCAGGTGGTGCTGTATAAAATGGTCAGTTCAC
GGACTGGGAACAGGGGGGCGTTTTCTTGGAGAAAGGACCCCTGGCTGGGGAGGAAGCCTGCATC
TGCCCACCGCAGCCCTCGTTTCCACAGTGAACTTGGATGCATTGATGAGGACTGGCCAATTCTG
AAGCGATGCTTGAGCAACACGACTGGAAAGTAAATGCAGACCAGGATGTTTTACTTTATTTTCT
TCTGCACGAGGCTTAGAGAAGCAGACCCAGGAGTAAAATTTTCCTTGAGAAAGCCAACGATTAC
CCTGGAGTAGAGAAGGGTCATGCGGTGCTACTGTATAAGGACAAATGAATCGCCTGAGGTCCAT
GGTGATGGCCACCATCCGGAGAATCCATCCAAACCATAAAAGCTCCAGGAAATTACAGGTCCCT
TGTGAGTTTCTTAAGAATACATCTAAAGGCCCAGCAATTTGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038302363	(Get FASTA)	NCBI Sequence Viewer
	XP_038376506	(Get FASTA)	NCBI Sequence Viewer
	XP_038440155	(Get FASTA)	NCBI Sequence Viewer
	XP_038504564	(Get FASTA)	NCBI Sequence Viewer
	XP_545353	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000014617.4
	ENSCAFP00000069519.1
	ENSCAFP00030015326.1
	ENSCAFP00040031137.1
	ENSCAFP00845033713.1
	ENSCAFP00845033787
	ENSCAFP00845033787.1

RefSeq Acc Id:

XP_545353 ⟸ XM_545353

- UniProtKB:

A0A8C0KFM3 (UniProtKB/TrEMBL), A0A8C0MVF2 (UniProtKB/TrEMBL), A0A8I3PQD8 (UniProtKB/TrEMBL), A0A8C0Z227 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPRIDADLKLDFKDVLLRPKRSSLRSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMA
VVMSQHSMFTAVHKHYTLDDWKLFAAHHPECLQHVAVSSGSGKSDLEKMSGILEAVPQVKFICL
DVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKT
GVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVI
EKNGQKLKLFYGMSSETAMKKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVG
AAKLKELSRRATFIRVTQQHNTVFS

hide sequence

RefSeq Acc Id:

ENSCAFP00000014617 ⟸ ENSCAFT00000015790

RefSeq Acc Id:

XP_038376506 ⟸ XM_038520578

RefSeq Acc Id:

XP_038504564 ⟸ XM_038648636

RefSeq Acc Id:	XP_038302363 ⟸ XM_038446435
- UniProtKB:	A0A8C0KFM3 (UniProtKB/TrEMBL), A0A8C0MVF2 (UniProtKB/TrEMBL), A0A8I3PQD8 (UniProtKB/TrEMBL), A0A8C0Z227 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038440155 ⟸ XM_038584227
- UniProtKB:	A0A8C0KFM3 (UniProtKB/TrEMBL), A0A8C0MVF2 (UniProtKB/TrEMBL), A0A8C0Z227 (UniProtKB/TrEMBL), A0A8I3PQD8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845033713 ⟸ ENSCAFT00845042999

RefSeq Acc Id:

ENSCAFP00845033787 ⟸ ENSCAFT00845043098

Protein Domains

IMP dehydrogenase/GMP reductase

Promoters

RGD ID:

13688977

Promoter ID:

EPDNEW_C7044

Type:

initiation region

Name:

GMPR_1

Description:

guanosine monophosphate reductase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	35	15,400,979 - 15,401,039	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000009920	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030009480	UniProtKB/TrEMBL
	ENSCAFG00040019322	UniProtKB/TrEMBL
	ENSCAFG00845024346	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000015790.5	UniProtKB/TrEMBL
	ENSCAFT00000108123.1	UniProtKB/TrEMBL
	ENSCAFT00030017546.1	UniProtKB/TrEMBL
	ENSCAFT00040035749.1	UniProtKB/TrEMBL
	ENSCAFT00845042999.1	UniProtKB/TrEMBL
	ENSCAFT00845043098	ENTREZGENE
	ENSCAFT00845043098.1	UniProtKB/TrEMBL
Gene3D-CATH	3.20.20.70	UniProtKB/TrEMBL
InterPro	Aldolase_TIM	UniProtKB/TrEMBL
	GMPR	UniProtKB/TrEMBL
	IMP_DH/GMP_Rdtase_CS	UniProtKB/TrEMBL
	IMP_DH_GMPRt	UniProtKB/TrEMBL
KEGG Report	cfa:488231	UniProtKB/TrEMBL
NCBI Gene	GMPR	ENTREZGENE
PANTHER	GMP REDUCTASE	UniProtKB/TrEMBL
	GMP REDUCTASE 1	UniProtKB/TrEMBL
Pfam	IMPDH	UniProtKB/TrEMBL
PIRSF	GMP_reductase	UniProtKB/TrEMBL
PROSITE	IMP_DH_GMP_RED	UniProtKB/TrEMBL
SMART	IMPDH	UniProtKB/TrEMBL
Superfamily-SCOP	Inosine monophosphate dehydrogenase (IMPDH)	UniProtKB/TrEMBL
UniProt	A0A8C0KFM3	ENTREZGENE
	A0A8C0MVF2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Z227	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PQD8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PR79_CANLF	UniProtKB/TrEMBL
	A0A8P0SEX1_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:41294	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - CTD

Imported Annotations - SMPDB