COPRS (coordinator of PRMT5 and differentiation stimulator) - Rat Genome Database

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Gene: COPRS (coordinator of PRMT5 and differentiation stimulator) Canis lupus familiaris
Analyze
Symbol: COPRS
Name: coordinator of PRMT5 and differentiation stimulator
RGD ID: 12246600
Description: ENCODES a protein that exhibits histone binding (inferred); INVOLVED IN blastocyst hatching (ortholog); muscle organ development (ortholog); ASSOCIATED WITH cerebral palsy (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C9H17orf79
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1941,098,226 - 41,104,035 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl941,102,541 - 41,103,994 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha940,256,947 - 40,263,241 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0941,916,297 - 41,922,540 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl941,916,381 - 41,922,353 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1940,700,384 - 40,706,646 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0940,994,614 - 41,000,887 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0941,070,836 - 41,077,080 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
COPRS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1941,098,226 - 41,104,035 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl941,102,541 - 41,103,994 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha940,256,947 - 40,263,241 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0941,916,297 - 41,922,540 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl941,916,381 - 41,922,353 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1940,700,384 - 40,706,646 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0940,994,614 - 41,000,887 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0941,070,836 - 41,077,080 (+)NCBIUU_Cfam_GSD_1.0
COPRS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381731,851,871 - 31,859,244 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1731,851,871 - 31,859,291 (-)EnsemblGRCh38hg38GRCh38
GRCh371730,178,890 - 30,186,263 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361727,203,009 - 27,210,369 (-)NCBINCBI36Build 36hg18NCBI36
Celera1727,098,524 - 27,105,966 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1726,389,213 - 26,396,656 (-)NCBIHuRef
CHM1_11730,241,346 - 30,248,795 (-)NCBICHM1_1
T2T-CHM13v2.01732,797,708 - 32,805,083 (-)NCBIT2T-CHM13v2.0
Coprs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,934,787 - 13,940,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,934,794 - 13,940,281 (-)EnsemblGRCm39 Ensembl
GRCm38813,884,787 - 13,890,352 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,884,794 - 13,890,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv37813,884,788 - 13,890,271 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,884,772 - 13,890,247 (-)NCBIMGSCv36mm8
Celera814,045,092 - 14,050,575 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map86.41NCBI
Coprs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81682,423,426 - 82,428,821 (+)NCBIGRCr8
mRatBN7.21675,721,264 - 75,726,375 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1675,720,061 - 75,726,375 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,001,741 - 81,006,842 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01684,455,271 - 84,460,372 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01679,705,058 - 79,710,142 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01680,826,681 - 80,831,791 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1680,826,681 - 80,831,791 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01680,390,902 - 80,396,012 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41680,557,030 - 80,562,140 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1673,530,152 - 73,535,262 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
Coprs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554816,787,135 - 6,800,696 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554816,794,088 - 6,797,723 (-)NCBIChiLan1.0ChiLan1.0
COPRS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21932,614,253 - 32,621,661 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11734,493,134 - 34,500,544 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01724,931,356 - 24,938,763 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11725,669,899 - 25,676,859 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1725,669,899 - 25,676,859 (+)Ensemblpanpan1.1panPan2
COPRS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1243,091,176 - 43,097,994 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11243,091,181 - 43,097,998 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21244,879,988 - 44,886,782 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COPRS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11625,327,180 - 25,334,493 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1625,327,134 - 25,334,413 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660754,743,159 - 4,750,495 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coprs
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248754,345,599 - 4,352,081 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248754,345,593 - 4,352,097 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in COPRS
92 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 21 5 6 5 6 4 12 8 10 6
Low 1 1 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029401   ⟹   ENSCAFP00000027336
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl941,102,541 - 41,103,994 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845025055   ⟹   ENSCAFP00845019714
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl941,916,381 - 41,922,353 (+)Ensembl
RefSeq Acc Id: XM_038486352   ⟹   XP_038342280
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1940,700,384 - 40,706,646 (+)NCBI
RefSeq Acc Id: XM_038548188   ⟹   XP_038404116
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0941,070,836 - 41,077,080 (+)NCBI
RefSeq Acc Id: XM_038610104   ⟹   XP_038466032
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha940,256,947 - 40,263,241 (+)NCBI
RefSeq Acc Id: XM_038612151   ⟹   XP_038468079
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0940,994,614 - 41,000,887 (+)NCBI
RefSeq Acc Id: XM_038677406   ⟹   XP_038533334
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0941,916,297 - 41,922,540 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000027336   ⟸   ENSCAFT00000029401
RefSeq Acc Id: XP_038342280   ⟸   XM_038486352
RefSeq Acc Id: XP_038468079   ⟸   XM_038612151
RefSeq Acc Id: XP_038533334   ⟸   XM_038677406
- UniProtKB: A0A8C0SP97 (UniProtKB/TrEMBL),   A0A8I3NGD9 (UniProtKB/TrEMBL),   A0A8C0NUK7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038466032   ⟸   XM_038610104
- UniProtKB: A0A8C0SP97 (UniProtKB/TrEMBL),   A0A8I3NGD9 (UniProtKB/TrEMBL),   A0A8C0NUK7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404116   ⟸   XM_038548188
- UniProtKB: A0A8C0NUK7 (UniProtKB/TrEMBL),   A0A8C0SP97 (UniProtKB/TrEMBL),   A0A8I3NGD9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845019714   ⟸   ENSCAFT00845025055


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018517 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030019463 UniProtKB/TrEMBL
  ENSCAFG00040015445 UniProtKB/TrEMBL
  ENSCAFG00845014015 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029401.5 UniProtKB/TrEMBL
  ENSCAFT00030035736.1 UniProtKB/TrEMBL
  ENSCAFT00040028432.1 UniProtKB/TrEMBL
  ENSCAFT00845025055 ENTREZGENE
  ENSCAFT00845025055.1 UniProtKB/TrEMBL
InterPro COPR5 UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
NCBI Gene COPRS ENTREZGENE
PANTHER COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR UniProtKB/TrEMBL
  PTHR36461 UniProtKB/TrEMBL
Pfam COPR5 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
UniProt A0A8C0NUK7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SP97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NGD9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:55562 ENTREZGENE