PURA (purine rich element binding protein A) - Rat Genome Database

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Gene: PURA (purine rich element binding protein A) Canis lupus familiaris
Analyze
Symbol: PURA
Name: purine rich element binding protein A
RGD ID: 12204491
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cell population proliferation (ortholog); epithelial cell proliferation (ortholog); lymphocyte proliferation (ortholog); ASSOCIATED WITH Apnea (ortholog); autosomal dominant intellectual developmental disorder 31 (ortholog); Boucher-Neuhauser syndrome (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcriptional activator protein Pur-alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,325,630 - 35,345,366 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,330,902 - 35,332,835 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,434,696 - 32,449,319 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,787,240 - 35,801,863 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,787,255 - 35,788,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,839,467 - 32,854,084 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,706,906 - 33,721,528 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,457,817 - 34,472,443 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PURA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,325,630 - 35,345,366 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,330,902 - 35,332,835 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,434,696 - 32,449,319 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,787,240 - 35,801,863 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,787,255 - 35,788,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,839,467 - 32,854,084 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,706,906 - 33,721,528 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,457,817 - 34,472,443 (+)NCBIUU_Cfam_GSD_1.0
PURA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,114,109 - 140,125,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,107,777 - 140,125,619 (+)EnsemblGRCh38hg38GRCh38
GRCh375139,493,694 - 139,505,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,473,892 - 139,476,505 (+)NCBINCBI36Build 36hg18NCBI36
Build 345139,473,891 - 139,475,030NCBI
Celera5135,569,524 - 135,572,137 (+)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5134,636,880 - 134,642,173 (+)NCBIHuRef
CHM1_15138,926,813 - 138,932,106 (+)NCBICHM1_1
T2T-CHM13v2.05140,639,205 - 140,650,714 (+)NCBIT2T-CHM13v2.0
Pura
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,413,614 - 36,434,575 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,414,150 - 36,425,588 (+)EnsemblGRCm39 Ensembl
GRCm381836,280,560 - 36,292,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,281,097 - 36,292,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,440,816 - 36,447,899 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,407,136 - 36,414,223 (+)NCBIMGSCv36mm8
Celera1836,723,061 - 36,744,137 (+)NCBICelera
Cytogenetic Map18B2NCBI
Pura
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,159,103 - 28,179,539 (+)NCBIGRCr8
mRatBN7.21827,885,071 - 27,905,509 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,884,556 - 27,905,513 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,012,429 - 28,032,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,774,266 - 28,794,712 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,109,203 - 28,129,639 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,103,850 - 29,110,215 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,110,242 - 29,111,156 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,817,907 - 28,820,657 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,916,722 - 28,925,008 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11828,948,984 - 28,950,043 (+)NCBI
Celera1827,615,341 - 27,621,754 (+)NCBICelera
Cytogenetic Map18p11NCBI
Pura
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955418538,883 - 548,605 (-)NCBIChiLan1.0ChiLan1.0
Pura
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,471,846 - 152,488,693 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,129,715 - 9,130,515 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,129,024 - 9,134,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PURA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,884,155 - 141,886,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12141,877,775 - 141,899,259 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,793,990 - 147,813,506 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PURA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,757,963 - 42,767,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,764,263 - 42,765,231 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603435,115,690 - 35,128,119 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pura
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,884,552 - 32,885,517 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474332,878,677 - 32,888,650 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PURA
87 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 16 1 12 9 1
Low 5 5 6 6 5 6 6 6 8 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000009238   ⟹   ENSCAFP00000008573
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl235,330,902 - 35,332,835 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845001969   ⟹   ENSCAFP00845001547
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl235,787,255 - 35,788,223 (+)Ensembl
RefSeq Acc Id: XM_005617272   ⟹   XP_005617329
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,325,630 - 35,345,366 (+)NCBI
Dog10K_Boxer_Tasha232,434,696 - 32,449,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038469554   ⟹   XP_038325482
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,839,467 - 32,854,084 (+)NCBI
RefSeq Acc Id: XM_038530317   ⟹   XP_038386245
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,457,817 - 34,472,443 (+)NCBI
RefSeq Acc Id: XM_038594565   ⟹   XP_038450493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,706,906 - 33,721,528 (+)NCBI
RefSeq Acc Id: XM_038658611   ⟹   XP_038514539
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,787,240 - 35,801,863 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005617329   ⟸   XM_005617272
- UniProtKB: A0A8C0QUA1 (UniProtKB/TrEMBL),   A0A8I3RPP8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000008573   ⟸   ENSCAFT00000009238
RefSeq Acc Id: XP_038325482   ⟸   XM_038469554
RefSeq Acc Id: XP_038450493   ⟸   XM_038594565
RefSeq Acc Id: XP_038514539   ⟸   XM_038658611
- UniProtKB: A0A8C0QUA1 (UniProtKB/TrEMBL),   A0A8I3RPP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386245   ⟸   XM_038530317
- UniProtKB: A0A8C0QUA1 (UniProtKB/TrEMBL),   A0A8I3RPP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001547   ⟸   ENSCAFT00845001969


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005735 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040003244 UniProtKB/TrEMBL
  ENSCAFG00845001158 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFG00845001165 ENTREZGENE
Ensembl Transcript ENSCAFT00000009238.6 UniProtKB/TrEMBL
  ENSCAFT00040006145.1 UniProtKB/TrEMBL
  ENSCAFT00845001969 ENTREZGENE
  ENSCAFT00845001969.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.700 UniProtKB/TrEMBL
  3.30.2450.30 UniProtKB/TrEMBL
InterPro PUR-bd_fam UniProtKB/TrEMBL
KEGG Report cfa:487159 UniProtKB/TrEMBL
NCBI Gene PURA ENTREZGENE
PANTHER PTHR12611 UniProtKB/TrEMBL
  PTHR12611:SF2 UniProtKB/TrEMBL
Pfam PurA UniProtKB/TrEMBL
SMART PUR UniProtKB/TrEMBL
UniProt A0A8C0Q0Y6_CANLF UniProtKB/TrEMBL
  A0A8C0QUA1 ENTREZGENE
  A0A8I3RPP8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8P0N8C2 UniProtKB/TrEMBL