MAEL (maelstrom spermatogenic transposon silencer)

Gene: MAEL (maelstrom spermatogenic transposon silencer) Canis lupus familiaris

Analyze

Symbol:

MAEL

Name:

maelstrom spermatogenic transposon silencer

RGD ID:

12191694

Description:

ENCODES a protein that exhibits DNA binding (inferred); sequence-specific DNA binding (inferred); INVOLVED IN apoptotic process (ortholog); cell morphogenesis (ortholog); DNA damage response (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); FOUND IN XY body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

maelstrom homolog; protein maelstrom homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	31,364,111 - 31,394,675 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	31,364,293 - 31,409,435 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	30,902,977 - 30,933,501 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	31,185,831 - 31,216,563 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	31,186,013 - 31,216,511 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	31,024,043 - 31,054,585 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	31,056,061 - 31,086,560 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	31,294,447 - 31,324,991 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA,ISO)

cell morphogenesis (IEA,ISO)

DNA damage response (IEA,ISO)

ectopic germ cell programmed cell death (IEA,ISO)

fertilization (IEA,ISO)

gene expression (IEA,ISO)

homologous chromosome pairing at meiosis (IEA,ISO)

intrinsic apoptotic signaling pathway in response to DNA damage (IEA,ISO)

male meiotic nuclear division (IEA,ISO)

meiotic cell cycle (IEA)

negative regulation of apoptotic process (IEA,ISO)

negative regulation of developmental process (IEA,ISO)

negative regulation of DNA-templated transcription (IEA)

negative regulation of gene expression (IEA,ISO)

negative regulation of reproductive process (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

piRNA processing (IEA)

regulation of miRNA-mediated gene silencing (IEA)

regulation of organ growth (IEA,ISO)

regulatory ncRNA-mediated gene silencing (IEA)

siRNA-mediated retrotransposon silencing by heterochromatin formation (IEA)

spermatogenesis (IEA,ISO)

Cellular Component

autosome (IEA)

chromatin (IEA)

chromatoid body (IEA)

cytoplasm (IEA)

male germ cell nucleus (IEA)

nucleus (IEA)

P granule (IEA)

perinuclear region of cytoplasm (IEA)

piP-body (IEA)

XY body (IEA,ISO)

Molecular Function

DNA binding (IEA)

protein binding (ISO)

sequence-specific DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

MAEL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	31,364,111 - 31,394,675 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	31,364,293 - 31,409,435 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	30,902,977 - 30,933,501 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	31,185,831 - 31,216,563 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	31,186,013 - 31,216,511 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	31,024,043 - 31,054,585 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	31,056,061 - 31,086,560 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	31,294,447 - 31,324,991 (-)	NCBI		UU_Cfam_GSD_1.0

MAEL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	166,975,582 - 167,022,214 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	166,975,582 - 167,022,214 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	166,944,819 - 166,991,451 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	165,225,143 - 165,258,071 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	140,063,652 - 140,096,580 (+)	NCBI		Celera
Cytogenetic Map	1	q24.1	NCBI
HuRef	1	138,205,402 - 138,238,333 (+)	NCBI		HuRef
CHM1_1	1	168,380,241 - 168,413,148 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	166,321,415 - 166,368,050 (+)	NCBI		T2T-CHM13v2.0

Mael
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	166,028,954 - 166,066,313 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	166,028,770 - 166,066,316 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	166,201,385 - 166,238,744 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	166,201,201 - 166,238,747 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	168,131,516 - 168,168,875 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	168,038,060 - 168,075,419 (-)	NCBI		MGSCv36	mm8
Celera	1	168,644,539 - 168,681,904 (-)	NCBI		Celera
Cytogenetic Map	1	H2.3	NCBI
cM Map	1	73.56	NCBI

Mael
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	80,990,040 - 81,029,623 (-)	NCBI		GRCr8
mRatBN7.2	13	78,457,073 - 78,496,657 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	78,457,073 - 78,496,657 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	81,075,679 - 81,115,104 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	82,380,128 - 82,419,556 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	79,627,923 - 79,667,349 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	84,412,569 - 84,452,140 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	84,383,670 - 84,452,181 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	89,287,037 - 89,326,509 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	81,935,141 - 81,975,026 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	81,949,328 - 81,989,225 (-)	NCBI
Celera	13	78,166,106 - 78,205,545 (-)	NCBI		Celera
Cytogenetic Map	13	q23	NCBI

Mael
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955462	9,903,006 - 9,934,570 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955462	9,902,978 - 9,934,814 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAEL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	82,754,407 - 82,855,308 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	82,421,170 - 82,523,713 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	142,341,646 - 142,442,521 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	146,191,664 - 146,228,669 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	146,195,482 - 146,228,669 (+)	Ensembl	panpan1.1		panPan2

Mael
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	101,056,496 - 101,081,300 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	18,903,153 - 18,928,195 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	18,903,153 - 18,928,195 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAEL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	83,990,273 - 84,040,465 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	83,990,266 - 84,040,465 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	91,716,539 - 91,722,861 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAEL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	62,011,292 - 62,057,860 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	62,011,651 - 62,044,529 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	63,748,036 - 63,795,033 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mael
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624826	5,066,235 - 5,103,220 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624826	5,066,587 - 5,103,108 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in MAEL
268 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium										8	5
Low	2	1	21	6	2	6	4	1	11		5	3
Below cutoff	3	4	1		4		2	5	1			3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014115214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038481291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038542652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038542653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038671476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038671477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_547484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000036916 ⟹ ENSCAFP00000032345

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	31,364,293 - 31,409,435 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000036917 ⟹ ENSCAFP00000032346

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	31,364,293 - 31,394,508 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845006554 ⟹ ENSCAFP00845005214

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	31,186,013 - 31,216,511 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845006561 ⟹ ENSCAFP00845005219

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	31,186,013 - 31,216,443 (-)	Ensembl

RefSeq Acc Id:

XM_014115214 ⟹ XP_013970689

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	31,364,111 - 31,394,675 (-)	NCBI
Dog10K_Boxer_Tasha	7	30,902,977 - 30,933,501 (-)	NCBI

Sequence:

show sequence

TCTCGGAGCGAGGCCAATGCGGCTGCGCACCGCGCCCTGATTGGTCCAGCGCTGTGGGCCTTGG
CGCGCAGGCGCCAGCCTCGGTTACTAAGGGCGGGAGCCCGGCGAGGGCGCCGGCGGCTTGTGCT
GTCTCTGGCGCAGGTTGTCGAATCCTGGCCTCGCTCGCCATGCCAAACCGCAGGGCCAGCCGTA
ATGCCTACTATTTCTTTGTGCAGGAGAAGATCCCCGAACTACGGCGGCGAGGCCTGCCTGTGGC
TCGCATAGCTGATGCCATCCCCTACTGCTCTGCTGACTGGGCGGTGAGACTGGAGCTTCTGAAG
GAGGAAGAAAAGGAGAAATACGCAGAAATGGCTCGAGAGTGGAGAGCAGCCCAGGGAAGGGACT
TTGGGCCTTCAGAGAAGCAGAAACCTGTTTCCACTCCACTGCGGCAGCCAGGCATGCTTGTACC
GAAGCAGAATGTTTCACCCCCGGATATGTCAAATTTGTCTCTAAAAAGTGATCAAGCTCTCCTT
GGAGGCATTTTTTATTTTTTGAACATTTTTAGCCATGGTGAGCTCCCTCCTCACTGTGAGCAGC
GCTTCCTCCCCTGTGAAATAGGGTGTGTTAAATACTCTCTCCAAGAAGGTATAATGGCAGAGTT
CCACAGATTTATAAATCCTGGTGAAATTCCACGAGGATTTCGGTTTCATTGTCAGGCTGCAAGT
GATTCTAGTCACAAGATTCCTATTTCAAACTTCGAATCTGGGTATGACCAAGCAACTGTGTTAC
AAAACCTTTATAGGTTTATTCACCCAAACCCGGGAAACTGGCCACTTATCTACTGCAAGTCTGA
TGACAGAGCCAGAGTCAACTGGTGTTTGAAGCATATGGCAAAGGCATCAGAAATCAGACAAGAT
CTAGAACTTCTCACTGTAGAAGATCTTGTAGTGGGAATCTACCAGCAAAAATTTCTTAAGGAGC
CCTCTAAAACCTGGGTTCGGAGCCTCCTAGATGTGGCCATGTGGGATTATTCTAGCAACACAAG
GTGCAAGTGGCATGAAGAAAACGATATTCTCTTCTGTGCTCTAGCTGTTTGCAAGAAAATTGCG
TACTGCATCAGTAACTCTCTGGCCACTCTCTTTGGAATCCAGCTCACAGATACTCATGTACCAC
TTCAAGATTATGAGGCCAGCAATAGTGTGACACCCAAAATGGTTGTATTGGATGCAGGGCGTTA
CCAGAAGCTAAGGGTTGAGAGTTCAGGATTTTCTCATTTCAGTTCTTCTAATCAGGAACAAAGA
TCAAACCCACCCACTGGTGACTATCCATCTGGGGTGAAAATTTCTGGCCAAAACAGCAGTGTTC
GGGGAAGAGGGATTACCCGCTTACTAGAGAGCATCTCCAGTTCCTCCAGCAATAGCCACAAATT
CTCCAACTGTGAGACTGCACTCTCACCTTACATGTCCCAAAAAGATGGATACAAATCTTTCTCT
TCCTTATCTTAATGATGGTACTTTTTTCAATTTCTGGAAAAATAACAAGCCCAACTTCCCTTTT
GACTACAGTCATATTAAACAGATCACATCAATGATAAATGTTGCCACTGTAAAAACTACTTAAT
TTGTAAGGAAATTCTGTTTCATAGTAAAAATAATTGTGGTTGGAGAAGATCTTGGGATTTTTGC
TTTTCTTTTTGCTTTTTTGTGGGGTTGTTCTACTTCCTGACTGTATGGTGTGAACACCATTAAA
GTTTTTAAGTCCTTTAAGAACAAAA

hide sequence

RefSeq Acc Id:

XM_038481291 ⟹ XP_038337219

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	31,024,043 - 31,054,585 (-)	NCBI

RefSeq Acc Id:

XM_038542652 ⟹ XP_038398580

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	31,294,447 - 31,324,991 (-)	NCBI

RefSeq Acc Id:

XM_038542653 ⟹ XP_038398581

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	31,294,447 - 31,324,989 (-)	NCBI

RefSeq Acc Id:

XM_038606805 ⟹ XP_038462733

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	31,056,061 - 31,086,560 (-)	NCBI

RefSeq Acc Id:

XM_038606806 ⟹ XP_038462734

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	31,056,061 - 31,086,557 (-)	NCBI

RefSeq Acc Id:

XM_038671476 ⟹ XP_038527404

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	31,185,831 - 31,216,563 (-)	NCBI

RefSeq Acc Id:

XM_038671477 ⟹ XP_038527405

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	31,185,831 - 31,216,561 (-)	NCBI

RefSeq Acc Id:

XM_547484 ⟹ XP_547484

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	31,364,111 - 31,394,673 (-)	NCBI
Dog10K_Boxer_Tasha	7	30,902,977 - 30,933,499 (-)	NCBI

Sequence:

show sequence

TCGGAGCGAGGCCAATGCGGCTGCGCACCGCGCCCTGATTGGTCCAGCGCTGTGGGCCTTGGCG
CGCAGGCGCCAGCCTCGGTTACTAAGGGCGGGAGCCCGGCGAGGGCGCCGGCGGCTTGTGCTGT
CTCTGGCGCAGGTTGTCGAATCCTGGCCTCGCTCGCCATGCCAAACCGCAGGGCCAGCCGTAAT
GCCTACTATTTCTTTGTGCAGGAGAAGATCCCCGAACTACGGCGGCGAGGCCTGCCTGTGGCTC
GCATAGCTGATGCCATCCCCTACTGCTCTGCTGACTGGGCGCTTCTGAAGGAGGAAGAAAAGGA
GAAATACGCAGAAATGGCTCGAGAGTGGAGAGCAGCCCAGGGAAGGGACTTTGGGCCTTCAGAG
AAGCAGAAACCTGTTTCCACTCCACTGCGGCAGCCAGGCATGCTTGTACCGAAGCAGAATGTTT
CACCCCCGGATATGTCAAATTTGTCTCTAAAAAGTGATCAAGCTCTCCTTGGAGGCATTTTTTA
TTTTTTGAACATTTTTAGCCATGGTGAGCTCCCTCCTCACTGTGAGCAGCGCTTCCTCCCCTGT
GAAATAGGGTGTGTTAAATACTCTCTCCAAGAAGGTATAATGGCAGAGTTCCACAGATTTATAA
ATCCTGGTGAAATTCCACGAGGATTTCGGTTTCATTGTCAGGCTGCAAGTGATTCTAGTCACAA
GATTCCTATTTCAAACTTCGAATCTGGGTATGACCAAGCAACTGTGTTACAAAACCTTTATAGG
TTTATTCACCCAAACCCGGGAAACTGGCCACTTATCTACTGCAAGTCTGATGACAGAGCCAGAG
TCAACTGGTGTTTGAAGCATATGGCAAAGGCATCAGAAATCAGACAAGATCTAGAACTTCTCAC
TGTAGAAGATCTTGTAGTGGGAATCTACCAGCAAAAATTTCTTAAGGAGCCCTCTAAAACCTGG
GTTCGGAGCCTCCTAGATGTGGCCATGTGGGATTATTCTAGCAACACAAGGTGCAAGTGGCATG
AAGAAAACGATATTCTCTTCTGTGCTCTAGCTGTTTGCAAGAAAATTGCGTACTGCATCAGTAA
CTCTCTGGCCACTCTCTTTGGAATCCAGCTCACAGATACTCATGTACCACTTCAAGATTATGAG
GCCAGCAATAGTGTGACACCCAAAATGGTTGTATTGGATGCAGGGCGTTACCAGAAGCTAAGGG
TTGAGAGTTCAGGATTTTCTCATTTCAGTTCTTCTAATCAGGAACAAAGATCAAACCCACCCAC
TGGTGACTATCCATCTGGGGTGAAAATTTCTGGCCAAAACAGCAGTGTTCGGGGAAGAGGGATT
ACCCGCTTACTAGAGAGCATCTCCAGTTCCTCCAGCAATAGCCACAAATTCTCCAACTGTGAGA
CTGCACTCTCACCTTACATGTCCCAAAAAGATGGATACAAATCTTTCTCTTCCTTATCTTAATG
ATGGTACTTTTTTCAATTTCTGGAAAAATAACAAGCCCAACTTCCCTTTTGACTACAGTCATAT
TAAACAGATCACATCAATGATAAATGTTGCCACTGTAAAAACTACTTAATTTGTAAGGAAATTC
TGTTTCATAGTAAAAATAATTGTGGTTGGAGAAGATCTTGGGATTTTTGCTTTTCTTTTTGCTT
TTTTGTGGGGTTGTTCTACTTCCTGACTGTATGGTGTGAACACCATTAAAGTTTTTAAGTCCTT
TAAGAACAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013970689	(Get FASTA)	NCBI Sequence Viewer
	XP_038337219	(Get FASTA)	NCBI Sequence Viewer
	XP_038398580	(Get FASTA)	NCBI Sequence Viewer
	XP_038398581	(Get FASTA)	NCBI Sequence Viewer
	XP_038462733	(Get FASTA)	NCBI Sequence Viewer
	XP_038462734	(Get FASTA)	NCBI Sequence Viewer
	XP_038527404	(Get FASTA)	NCBI Sequence Viewer
	XP_038527405	(Get FASTA)	NCBI Sequence Viewer
	XP_547484	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000032345.4
	ENSCAFP00000032346.3
	ENSCAFP00030035982.1
	ENSCAFP00030036004.1
	ENSCAFP00040003572.1
	ENSCAFP00845005214
	ENSCAFP00845005214.1
	ENSCAFP00845005219.1

RefSeq Acc Id:	XP_547484 ⟸ XM_547484
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LBM2 (UniProtKB/TrEMBL), A0A8C0RR38 (UniProtKB/TrEMBL), A0A8I3RRJ4 (UniProtKB/TrEMBL), A0A8C0PST4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPNRRASRNAYYFFVQEKIPELRRRGLPVARIADAIPYCSADWALLKEEEKEKYAEMAREWRAA QGRDFGPSEKQKPVSTPLRQPGMLVPKQNVSPPDMSNLSLKSDQALLGGIFYFLNIFSHGELPP HCEQRFLPCEIGCVKYSLQEGIMAEFHRFINPGEIPRGFRFHCQAASDSSHKIPISNFESGYDQ ATVLQNLYRFIHPNPGNWPLIYCKSDDRARVNWCLKHMAKASEIRQDLELLTVEDLVVGIYQQK FLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTD THVPLQDYEASNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNPPTGDYPSGVKISGQ NSSVRGRGITRLLESISSSSSNSHKFSNCETALSPYMSQKDGYKSFSSLS hide sequence

RefSeq Acc Id:	XP_013970689 ⟸ XM_014115214
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PST4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPNRRASRNAYYFFVQEKIPELRRRGLPVARIADAIPYCSADWAVRLELLKEEEKEKYAEMARE WRAAQGRDFGPSEKQKPVSTPLRQPGMLVPKQNVSPPDMSNLSLKSDQALLGGIFYFLNIFSHG ELPPHCEQRFLPCEIGCVKYSLQEGIMAEFHRFINPGEIPRGFRFHCQAASDSSHKIPISNFES GYDQATVLQNLYRFIHPNPGNWPLIYCKSDDRARVNWCLKHMAKASEIRQDLELLTVEDLVVGI YQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGI QLTDTHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNPPTGDYPSGVK ISGQNSSVRGRGITRLLESISSSSSNSHKFSNCETALSPYMSQKDGYKSFSSLS hide sequence

RefSeq Acc Id:

ENSCAFP00000032345 ⟸ ENSCAFT00000036916

RefSeq Acc Id:

ENSCAFP00000032346 ⟸ ENSCAFT00000036917

RefSeq Acc Id:	XP_038337219 ⟸ XM_038481291
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038462733 ⟸ XM_038606805
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038462734 ⟸ XM_038606806
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038527404 ⟸ XM_038671476
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PST4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038527405 ⟸ XM_038671477
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LBM2 (UniProtKB/TrEMBL), A0A8C0RR38 (UniProtKB/TrEMBL), A0A8I3RRJ4 (UniProtKB/TrEMBL), A0A8C0PST4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038398580 ⟸ XM_038542652
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PST4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038398581 ⟸ XM_038542653
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LBM2 (UniProtKB/TrEMBL), A0A8C0PST4 (UniProtKB/TrEMBL), A0A8C0RR38 (UniProtKB/TrEMBL), A0A8I3RRJ4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845005219 ⟸ ENSCAFT00845006561

RefSeq Acc Id:

ENSCAFP00845005214 ⟸ ENSCAFT00845006554

Protein Domains

HMG box Maelstrom

Promoters

RGD ID:

13683963

Promoter ID:

EPDNEW_C2031

Type:

single initiation site

Name:

MAEL_1

Description:

maelstrom spermatogenic transposon silencer

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	31,394,586 - 31,394,646	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000015596	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030022396	UniProtKB/TrEMBL
	ENSCAFG00040002188	UniProtKB/TrEMBL
	ENSCAFG00845003655	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000036916.5	UniProtKB/TrEMBL
	ENSCAFT00000036917.4	UniProtKB/TrEMBL
	ENSCAFT00030041235.1	UniProtKB/TrEMBL
	ENSCAFT00030041267.1	UniProtKB/TrEMBL
	ENSCAFT00040004168.1	UniProtKB/TrEMBL
	ENSCAFT00845006554	ENTREZGENE
	ENSCAFT00845006554.1	UniProtKB/TrEMBL
	ENSCAFT00845006561.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.30.10	UniProtKB/TrEMBL
InterPro	HMG_box_dom	UniProtKB/TrEMBL
	HMG_box_dom_sf	UniProtKB/TrEMBL
	Maelstrom	UniProtKB/TrEMBL
	Protein_maelstrom	UniProtKB/TrEMBL
NCBI Gene	MAEL	ENTREZGENE
PANTHER	PROTEIN MAELSTROM HOMOLOG	UniProtKB/TrEMBL
	PTHR21358	UniProtKB/TrEMBL
Pfam	HMG_box_2	UniProtKB/TrEMBL
	Maelstrom	UniProtKB/TrEMBL
PROSITE	HMG_BOX_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47095	UniProtKB/TrEMBL
UniProt	A0A8C0LBM2	ENTREZGENE
	A0A8C0PST4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RR38	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RR89_CANLF	UniProtKB/TrEMBL
	A0A8I3MPT5_CANLF	UniProtKB/TrEMBL
	A0A8I3RRJ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SQI0_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:42919	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar