NFATC2IP (nuclear factor of activated T cells 2 interacting protein) - Rat Genome Database

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Gene: NFATC2IP (nuclear factor of activated T cells 2 interacting protein) Canis lupus familiaris
Analyze
Symbol: NFATC2IP
Name: nuclear factor of activated T cells 2 interacting protein
RGD ID: 12191266
Description: INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH chromosome 16p11.2 deletion syndrome, 220-kb (ortholog); chromosome 16p11.2 deletion syndrome, 593-kb (ortholog); neuronal ceroid lipofuscinosis (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,433,421 - 18,444,148 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,432,809 - 18,443,922 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha620,010,538 - 20,021,071 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,568,330 - 18,578,618 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,568,326 - 18,578,853 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,367,822 - 18,378,323 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,282,398 - 18,293,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,599,007 - 18,609,523 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NFATC2IP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,433,421 - 18,444,148 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,432,809 - 18,443,922 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha620,010,538 - 20,021,071 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,568,330 - 18,578,618 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,568,326 - 18,578,853 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,367,822 - 18,378,323 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,282,398 - 18,293,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,599,007 - 18,609,523 (+)NCBIUU_Cfam_GSD_1.0
NFATC2IP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,950,937 - 28,967,092 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,950,807 - 28,967,092 (+)EnsemblGRCh38hg38GRCh38
GRCh371628,962,258 - 28,978,413 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,869,819 - 28,885,287 (+)NCBINCBI36Build 36hg18NCBI36
Build 341628,869,818 - 28,885,266NCBI
Celera1627,917,598 - 27,932,949 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1626,830,232 - 26,845,660 (+)NCBIHuRef
CHM1_11629,974,092 - 29,989,542 (+)NCBICHM1_1
T2T-CHM13v2.01629,232,053 - 29,248,207 (+)NCBIT2T-CHM13v2.0
Nfatc2ip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397125,982,025 - 125,995,909 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7125,982,026 - 125,995,909 (-)EnsemblGRCm39 Ensembl
GRCm387126,382,853 - 126,396,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,382,854 - 126,396,737 (-)EnsemblGRCm38mm10GRCm38
MGSCv377133,526,368 - 133,540,251 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,174,002 - 126,187,885 (-)NCBIMGSCv36mm8
Celera7126,235,073 - 126,249,025 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.01NCBI
Nfatc2ip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,385,416 - 190,403,309 (-)NCBIGRCr8
mRatBN7.21180,954,834 - 180,971,847 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,955,043 - 180,971,747 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,287,910 - 189,302,918 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,473,958 - 196,488,989 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,161,418 - 189,176,411 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01197,785,966 - 197,800,943 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1197,785,968 - 197,801,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,765,444 - 204,783,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,470,915 - 185,485,794 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11185,620,796 - 185,635,675 (-)NCBI
Celera1178,617,187 - 178,632,065 (-)NCBICelera
Cytogenetic Map1q36NCBI
Nfatc2ip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554936,522,604 - 6,527,999 (-)NCBIChiLan1.0ChiLan1.0
NFATC2IP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21832,124,276 - 32,140,387 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11636,942,260 - 36,958,373 (+)NCBINHGRI_mPanPan1
Nfatc2ip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344123,678,509 - 123,687,703 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650111,776,031 - 11,785,644 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650111,776,037 - 11,785,566 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFATC2IP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,609,912 - 18,622,640 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,609,943 - 18,624,150 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,796,316 - 18,809,626 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NFATC2IP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,105,784 - 26,120,025 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,103,107 - 26,119,963 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660683,507,885 - 3,522,025 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfatc2ip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478212,817,110 - 12,826,309 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478212,814,214 - 12,826,233 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NFATC2IP
88 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 2 4 6 5 8 5
Low 4 5 20 6 2 6 6 7 5 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000027416   ⟹   ENSCAFP00000025496
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl618,432,809 - 18,443,922 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000090839   ⟹   ENSCAFP00000048664
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl618,434,430 - 18,442,483 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845006489   ⟹   ENSCAFP00845005162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl618,568,326 - 18,578,853 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845006512   ⟹   ENSCAFP00845005183
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl618,568,326 - 18,578,629 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845006530   ⟹   ENSCAFP00845005199
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl618,569,339 - 18,578,853 (+)Ensembl
RefSeq Acc Id: XM_003639135   ⟹   XP_003639183
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1618,433,421 - 18,444,148 (+)NCBI
Dog10K_Boxer_Tasha620,010,538 - 20,021,071 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038478723   ⟹   XP_038334651
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1618,367,822 - 18,378,323 (+)NCBI
RefSeq Acc Id: XM_038539968   ⟹   XP_038395896
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0618,599,007 - 18,609,523 (+)NCBI
RefSeq Acc Id: XM_038604045   ⟹   XP_038459973
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0618,282,398 - 18,293,114 (+)NCBI
RefSeq Acc Id: XM_038668765   ⟹   XP_038524693
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0618,568,330 - 18,578,618 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003639183   ⟸   XM_003639135
- UniProtKB: A0A8C0RVC3 (UniProtKB/TrEMBL),   A0A8I3MQC4 (UniProtKB/TrEMBL),   A0A8C0RVC1 (UniProtKB/TrEMBL),   A0A8I3MPQ5 (UniProtKB/TrEMBL),   A0A8P0SLL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000025496   ⟸   ENSCAFT00000027416
RefSeq Acc Id: ENSCAFP00000048664   ⟸   ENSCAFT00000090839
RefSeq Acc Id: XP_038334651   ⟸   XM_038478723
RefSeq Acc Id: XP_038459973   ⟸   XM_038604045
RefSeq Acc Id: XP_038524693   ⟸   XM_038668765
- UniProtKB: A0A8C0RVC3 (UniProtKB/TrEMBL),   A0A8I3MQC4 (UniProtKB/TrEMBL),   A0A8C0RVC1 (UniProtKB/TrEMBL),   A0A8I3MPQ5 (UniProtKB/TrEMBL),   A0A8P0SLL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395896   ⟸   XM_038539968
- UniProtKB: A0A8C0RVC1 (UniProtKB/TrEMBL),   A0A8C0RVC3 (UniProtKB/TrEMBL),   A0A8I3MPQ5 (UniProtKB/TrEMBL),   A0A8I3MQC4 (UniProtKB/TrEMBL),   A0A8P0SLL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845005183   ⟸   ENSCAFT00845006512
RefSeq Acc Id: ENSCAFP00845005199   ⟸   ENSCAFT00845006530
RefSeq Acc Id: ENSCAFP00845005162   ⟸   ENSCAFT00845006489
Protein Domains
Ubiquitin-like

Promoters
RGD ID:13683641
Promoter ID:EPDNEW_C1709
Type:single initiation site
Name:NFATC2IP_1
Description:nuclear factor of activated T cells 2 interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1618,433,414 - 18,433,474EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017306 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030024765 UniProtKB/TrEMBL
  ENSCAFG00040001445 UniProtKB/TrEMBL
  ENSCAFG00845003632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027416.6 UniProtKB/TrEMBL
  ENSCAFT00000100153.1 UniProtKB/TrEMBL
  ENSCAFT00000107119.1 UniProtKB/TrEMBL
  ENSCAFT00030045615.1 UniProtKB/TrEMBL
  ENSCAFT00030045645.1 UniProtKB/TrEMBL
  ENSCAFT00040002734.1 UniProtKB/TrEMBL
  ENSCAFT00040002746.1 UniProtKB/TrEMBL
  ENSCAFT00040002753.1 UniProtKB/TrEMBL
  ENSCAFT00845006489 ENTREZGENE
  ENSCAFT00845006489.1 UniProtKB/TrEMBL
  ENSCAFT00845006512.1 UniProtKB/TrEMBL
  ENSCAFT00845006530.1 UniProtKB/TrEMBL
InterPro Rad60/SUMO-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report cfa:100856245 UniProtKB/TrEMBL
NCBI Gene NFATC2IP ENTREZGENE
PANTHER NFATC2-INTERACTING PROTEIN UniProtKB/TrEMBL
  NFATC2-INTERACTING PROTEIN UniProtKB/TrEMBL
Pfam Rad60-SLD UniProtKB/TrEMBL
PROSITE UBIQUITIN_2 UniProtKB/TrEMBL
SMART UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A8C0PPZ8_CANLF UniProtKB/TrEMBL
  A0A8C0RVC1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RVC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MPQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MQC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N675_CANLF UniProtKB/TrEMBL
  A0A8P0SLL4 ENTREZGENE
UniProt Secondary A0A8P0SLL4 UniProtKB/TrEMBL
VGNC ID VGNC:43768 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-19 NFATC2IP  nuclear factor of activated T cells 2 interacting protein    nuclear factor of activated T-cells 2 interacting protein  Symbol and/or name change 5135510 APPROVED