ALDH1L2 (aldehyde dehydrogenase 1 family member L2)

Gene: ALDH1L2 (aldehyde dehydrogenase 1 family member L2) Canis lupus familiaris

Analyze

Symbol:

ALDH1L2

Name:

aldehyde dehydrogenase 1 family member L2

RGD ID:

12171700

Description:

ENCODES a protein that exhibits aldehyde dehydrogenase (NAD+) activity (inferred); formyltetrahydrofolate dehydrogenase activity (inferred); oxidoreductase activity (inferred); INVOLVED IN fatty acid beta-oxidation (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mitochondrial 10-formyltetrahydrofolate dehydrogenase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	33,310,523 - 33,365,677 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	33,310,558 - 33,365,228 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	33,229,898 - 33,285,026 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	34,151,792 - 34,207,579 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	34,151,821 - 34,207,560 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	33,887,203 - 33,942,545 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	34,171,323 - 34,226,449 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	34,364,647 - 34,420,074 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

COVID-19 (ISO)

Experimental Liver Cirrhosis (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

10-formyltetrahydrofolate catabolic process (IEA)

biosynthetic process (IEA)

fatty acid beta-oxidation (IEA,ISO)

folic acid metabolic process (IEA)

NADPH regeneration (IEA)

one-carbon metabolic process (IEA)

Cellular Component

cytoplasm (IEA)

mitochondrion (IEA)

nucleoplasm (IEA)

Molecular Function

aldehyde dehydrogenase (NAD+) activity (IEA)

formyltetrahydrofolate dehydrogenase activity (IEA)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ALDH1L2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	33,310,523 - 33,365,677 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	33,310,558 - 33,365,228 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	33,229,898 - 33,285,026 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	34,151,792 - 34,207,579 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	34,151,821 - 34,207,560 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	33,887,203 - 33,942,545 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	34,171,323 - 34,226,449 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	34,364,647 - 34,420,074 (+)	NCBI		UU_Cfam_GSD_1.0

ALDH1L2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	105,019,790 - 105,084,458 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	105,019,784 - 105,107,643 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	105,413,568 - 105,478,236 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	103,942,332 - 104,002,366 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	105,078,239 - 105,142,624 (-)	NCBI		Celera
Cytogenetic Map	12	q23.3	NCBI
HuRef	12	102,472,652 - 102,538,019 (-)	NCBI		HuRef
CHM1_1	12	105,379,314 - 105,443,992 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	104,981,395 - 105,046,228 (-)	NCBI		T2T-CHM13v2.0

Aldh1l2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	83,320,386 - 83,370,008 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	83,323,314 - 83,370,004 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	83,487,447 - 83,534,146 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	83,487,450 - 83,534,140 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	82,950,192 - 82,996,885 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	82,917,249 - 82,963,861 (-)	NCBI		MGSCv36	mm8
Celera	10	85,474,860 - 85,521,640 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	41.27	NCBI

Aldh1l2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	22,141,872 - 22,193,403 (+)	NCBI		GRCr8
mRatBN7.2	7	20,254,246 - 20,305,793 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	20,254,233 - 20,305,776 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	22,226,671 - 22,277,861 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	24,389,426 - 24,440,621 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	24,166,438 - 24,217,632 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	26,375,866 - 26,425,838 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	26,375,866 - 26,425,108 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	26,506,321 - 26,555,206 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	22,398,067 - 22,450,381 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	22,418,181 - 22,469,924 (+)	NCBI
Celera	7	17,456,470 - 17,507,229 (+)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

Aldh1l2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	39,387,527 - 39,437,322 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955405	39,387,949 - 39,437,282 (-)	NCBI	ChiLan1.0	ChiLan1.0

ALDH1L2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	113,084,633 - 113,154,101 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	113,080,726 - 113,174,017 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	102,596,881 - 102,661,617 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	105,992,398 - 106,046,239 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	105,997,045 - 106,056,607 (-)	Ensembl	panpan1.1		panPan2

Aldh1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	16,595,327 - 16,651,070 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	9,605,708 - 9,657,743 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	9,605,611 - 9,657,717 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALDH1L2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	79,492,750 - 79,558,701 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	79,492,672 - 79,558,702 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	82,894,904 - 82,954,624 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALDH1L2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	100,242,649 - 100,311,164 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	100,247,262 - 100,298,621 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	144,713,789 - 144,779,293 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aldh1l2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	3,912,002 - 3,961,963 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624750	3,912,030 - 4,054,170 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ALDH1L2
661 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium		4	6						8	8		4
Low	5	1	11	1	6	1	6	6	4		10	2
Below cutoff			5	5		5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038488846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038550810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038614730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038680098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_531763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000003039 ⟹ ENSCAFP00000002821

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	33,310,558 - 33,365,228 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000067045 ⟹ ENSCAFP00000055109

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	10	33,310,558 - 33,363,431 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845011001 ⟹ ENSCAFP00845008586

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	10	34,151,821 - 34,207,560 (+)	Ensembl

RefSeq Acc Id:

XM_038488846 ⟹ XP_038344774

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	10	33,887,203 - 33,942,545 (+)	NCBI

RefSeq Acc Id:

XM_038550810 ⟹ XP_038406738

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	10	34,364,647 - 34,420,074 (+)	NCBI

RefSeq Acc Id:

XM_038614730 ⟹ XP_038470658

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	10	34,171,323 - 34,226,449 (+)	NCBI

RefSeq Acc Id:

XM_038680098 ⟹ XP_038536026

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	10	34,151,792 - 34,207,579 (+)	NCBI

RefSeq Acc Id:

XM_531763 ⟹ XP_531763

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	10	33,310,523 - 33,365,677 (+)	NCBI
Dog10K_Boxer_Tasha	10	33,229,898 - 33,285,026 (+)	NCBI

Sequence:

show sequence

GCCGCGAGCGCGGCGGCCCCGGCGCTGGGAGGTGGCAGGCCGCGCCCCGGCTGAGCCTCCGCTG
CGGTGCGGTGCGGCCCGGCCACGCGTCCCTTCCGGCATGCTGTGGCGCGGCAGCCAGGCGCTCC
GGCGCTTCTCCACCGGCCAGGCTTATTTCAAAAACAAGCTGAAGTTGGCACTTATTGGTCAGAG
CCTCTTTGGCCAGGAAGTCTACAGTCACCTCTGCAAAGAGGGCCACCGAGTTGTGGGTGTGTTC
ACGGTTCCAGACAAGGATGGAAAAGCCGACCCGCTGGCTCTAGCTGCAGAGAAAGATGGGACAC
CTGTGTTCAAGTTCCCCAGATGGAGAGTCAAGGGCAAGACCATAAAGGAGGTGGCGGAGGCCTA
CAAATCTGTGGGTGCTGAGCTAAACGTGCTTCCTTTCTGCACACAGTTTATCCCTATGGATGTA
ATTGACAGCCCAAAGCACGGTTCCATCATATATCACCCTTCCATCCTCCCCCGGCACAGAGGAG
CCTCTGCTATCAACTGGACTCTAATTATGGGAGACAAGAAAGCTGGGTTGTCTGTTTTCTGGGC
TGATGATGGTTTAGACACTGGACCCATCCTTCTTCAGAGGTCATGTGACGTTGAACCCAATGAT
ACAGTGGATGCACTTTATAATCGGTTTCTTTTTCCTGAAGGAATCAAGGCCATGGTGGAAGCTG
TCCAACTCATAGCCGATGGAAAAGCTCCTCGTATTCCCCAGCCAGAAGAAGGGGCAACGTATGA
AGGTATCCAGAAAAAGGAAAATGCTGAGATTTCTTGGGATCAGTCTGCCGAAGTTTTACATAAC
TGGATCCGAGGTCATGATAAAGTTCCTGGAGCTTGGACAGAGATAAACGGACAGATGGTCACGT
TCTATGGCTCATCATTACTGAAAAGCTCTGTGCCTCCTGGAGAACCACTGGAAATTAAAGGTGC
CAAGAAGCCTGGTCTTGTTACCAAAAATGGACTTGTTCTTTTTGGTAATGATGGAAAAGCACTG
ATGGTGAGAAATCTGCAGTTTGAAGATGGAAGAATGATTCCTGCTTCTCAGTACTTTTCAGCCG
GTGAGACATCAGTGGTAGAACTTACAGCCGAAGAGGTCAAGGTGGCAGGGACCATCAAGGTCAT
CTGGGCTGGAATTTTAAGCAATGTCCCTGTTATTGAAGACTCAACAGACTTCTTTAAATCTGGA
GCGAGCTCAATGGATGTTGTCAGGCTGGTTGAGGAGATCAGACAGAGGTGTGGTGGGCTTCAGC
TGCAGAACGAAGATGTCTATATGGCCACCAAGTTCGAAGACTTCATCCAAAAAGTCGTGAGGAA
ATTGAGAGGAGAAGATCAAGAAGTGGAACTAGTGGTGGATTATGTTTCAAAGGAGGTCAATGAA
ATGACCGTGAAAATGCCATATCAATGTTTCATAAATGGACAGTTCACAGATGCTAATGATGGAA
AGACCTATGATACTATCAACCCAACAGATGGATCTACAATATGCAAAGTATCCTATGCTTCTTT
GGTGGATGTTGATAAAGCAGTAGCAGCAGCAAAAGATGCCTTTGAAAAAGGTGAATGGGGAAGA
ATGAATGCAAGAGAAAGAGGAAGATTGATGTACAGACTTGCAGACCTCCTGGAAGAAAACCAGG
AAGAACTGGCAACCATTGAAGCCCTTGATTCAGGCGCTGTCTATACCCTGGCTCTGAAGACTCA
CATCGGAATGTCTGTGCAAACATTCAGATATTTTGCTGGCTGGTGTGACAAAATTCAGGGCTCT
ACCATTCCAATCAACCAAGCCCGTCCAAATCGCAATCTGACCTTCACCAAGAAGGAGCCACTTG
GTGTCTGTGCCATTATCATCCCCTGGAATTACCCACTGATGATGCTGGCATGGAAGAGCGCTGC
GTGTTTGGCAGCAGGCAATACCTTAGTGCTCAAGCCAGCACAGGTCACACCCTTGACTGCTTTG
AAGTTTGCTGAGCTCTCTTCGAAAGCAGGCTTTCCAAAGGGTGTAATCAACATCATTCCAGGCT
CAGGTGGTGTAGCCGGGCAACGCCTTTCTGAACATCCTCATATCCGCAAACTTGGCTTCACTGG
GTCCACTGCTATCGGCAAACAGATCATGAAGAGCTGTGCTGTGAGCAACTTGAAGAAAGTTTCC
CTTGAACTTGGTGGCAAATCCCCACTTATAATATTCAACGACTGTGAACTTGACAAGGCTGTGC
GAATGGGCATGGGGGCAGTATTTTTCAACAAAGGAGAGAATTGTATTGCAGCTGGGCGTTTGTT
TGTGGAAGAATCCATCCACGATGAATTTGTGACAAAAGTGGTAGAAGAAATTAAAAAGATGAAA
ATTGGTGATCCACTTGACAGATCTACAGATCACGGGCCCCAAAACCATCAGGCCCATCTGGAAA
AGCTTCTGCAATACTGTGAAGCTGGAGTGAAGGAAGGGGCCACCTTGGTGTATGGGGGAAGACA
AGTGTGCAGGCCAGGCTTTTTTATGGAGCCAACTGTGTTCACAGATGTGGAAGACCACATGTAT
CTTGCCAAAGAGGAATCATTTGGGCCTATTATGGTCATTTCTAAGTTCCAAAATGGGGACATCG
ATGGAGTGTTACAGCGAGCAAATAATACAGAGTATGGTCTGGCCTCAGGGGTTTTTACAAGAGA
CATCAATAAAGCCATGTATGTGAGCGAAAAACTCGAAGCAGGAACTGTTTTTGTTAACACGTAC
AACAAGACGGATGTGGCAGCCCCTTTCGGTGGAGTTAAACAATCGGGCTTCGGAAAAGACTTAG
GTGAGGAAGCTCTAAACGAATACCTCAAAACCAAGACGGTGACATTGGAATACTAGAGCTGTGC
CATCCCTGAGAAATCCTCGGCCGACAGCACCACTCCCGATCCCTCCACACACGTAGGAAGCCTG
GGTGTGCGGAGGGAAGGTGGATCTACCACGAGCCGATGCTGCACACGTGGACCCTAAAGGGGGT
CAGGCCACATCAAGCATTTTCACCTGTGCCTGTGTATTCTGATGCACCTTTTCTACCTTAAAAC
TATTTGAAGTGGTTGGGTTTTGACTGTGTTGTATACCCCACATATTTCTAAACTGCCAAGTTGC
TTTTTCTCCTAAGACTAATCTAGCCATTGTTGTTCATCTTGAAAAATGTCAGGATCAGGTGGTT
ATAATACACAAGGTGGGTTTGGGGGATACTTTGCATACTATGTGTAGGTTGTAACCTCTGAACT
ATACCTATGGGGCTATTAAAAAGGTTTTCTATAATTTTGCTCTCAAGGAACGTATATCCTATAA
GGAATGTGAAGTAAATTCCTTTTTTTTTTTCATATTTGGAAATAAGATACATCTTTGTGCCTTT
TGATGTTCTATTTTTCAGCCCACTGAGAATGAGTAACCCAAAACAGTGCTCGAGTACTTGCTAG
GTGTGAGGTACTAGGTAGTGTTCTGAGGAGTAGCCAGGACATAGTGACATTGTCTCTGGACTCA
AATAGCTTACATTCTAATAAAGAGCTTTTAAAAAGTGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038344774	(Get FASTA)	NCBI Sequence Viewer
	XP_038406738	(Get FASTA)	NCBI Sequence Viewer
	XP_038470658	(Get FASTA)	NCBI Sequence Viewer
	XP_038536026	(Get FASTA)	NCBI Sequence Viewer
	XP_531763	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000002821.3
	ENSCAFP00030040964.1
	ENSCAFP00040015464.1
	ENSCAFP00040015609.1
	ENSCAFP00845008586
	ENSCAFP00845008586.1

RefSeq Acc Id:	XP_531763 ⟸ XM_531763
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0YT63 (UniProtKB/TrEMBL), A0A8P0N521 (UniProtKB/TrEMBL), A0A8C0PNX7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLWRGSQALRRFSTGQAYFKNKLKLALIGQSLFGQEVYSHLCKEGHRVVGVFTVPDKDGKADPL ALAAEKDGTPVFKFPRWRVKGKTIKEVAEAYKSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYH PSILPRHRGASAINWTLIMGDKKAGLSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFP EGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAW TEINGQMVTFYGSSLLKSSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGRM IPASQYFSAGETSVVELTAEEVKVAGTIKVIWAGILSNVPVIEDSTDFFKSGASSMDVVRLVEE IRQRCGGLQLQNEDVYMATKFEDFIQKVVRKLRGEDQEVELVVDYVSKEVNEMTVKMPYQCFIN GQFTDANDGKTYDTINPTDGSTICKVSYASLVDVDKAVAAAKDAFEKGEWGRMNARERGRLMYR LADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRN LTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSSKAGFP KGVINIIPGSGGVAGQRLSEHPHIRKLGFTGSTAIGKQIMKSCAVSNLKKVSLELGGKSPLIIF NDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTKVVEEIKKMKIGDPLDRSTDHG PQNHQAHLEKLLQYCEAGVKEGATLVYGGRQVCRPGFFMEPTVFTDVEDHMYLAKEESFGPIMV ISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSEKLEAGTVFVNTYNKTDVAAPFGGV KQSGFGKDLGEEALNEYLKTKTVTLEY hide sequence

RefSeq Acc Id:

ENSCAFP00000002821 ⟸ ENSCAFT00000003039

RefSeq Acc Id:

ENSCAFP00000055109 ⟸ ENSCAFT00000067045

RefSeq Acc Id:	XP_038344774 ⟸ XM_038488846
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038470658 ⟸ XM_038614730
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038536026 ⟸ XM_038680098
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3N0G4 (UniProtKB/TrEMBL), A0A8C0PNX7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038406738 ⟸ XM_038550810
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0PNX7 (UniProtKB/TrEMBL), A0A8I3N0G4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845008586 ⟸ ENSCAFT00845011001

Protein Domains

Carrier

Promoters

RGD ID:

13685008

Promoter ID:

EPDNEW_C3075

Type:

initiation region

Name:

ALDH1L2_1

Description:

aldehyde dehydrogenase 1 family member L2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	10	33,310,532 - 33,310,592	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000001911	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030025328	UniProtKB/TrEMBL
	ENSCAFG00040009427	UniProtKB/TrEMBL
	ENSCAFG00845006151	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000003039.5	UniProtKB/TrEMBL
	ENSCAFT00030046870.1	UniProtKB/TrEMBL
	ENSCAFT00040017816.1	UniProtKB/TrEMBL
	ENSCAFT00040017978.1	UniProtKB/TrEMBL
	ENSCAFT00845011001	ENTREZGENE
	ENSCAFT00845011001.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1200.10	UniProtKB/TrEMBL
	3.10.25.10	UniProtKB/TrEMBL
	Formyl transferase, N-terminal domain	UniProtKB/TrEMBL
InterPro	10_FTHF_DH	UniProtKB/TrEMBL
	ACP-like_sf	UniProtKB/TrEMBL
	Ald_DH/histidinol_DH	UniProtKB/TrEMBL
	Ald_DH_C	UniProtKB/TrEMBL
	Ald_DH_CS_CYS	UniProtKB/TrEMBL
	Ald_DH_CS_GLU	UniProtKB/TrEMBL
	Ald_DH_N	UniProtKB/TrEMBL
	Aldehyde_DH_dom	UniProtKB/TrEMBL
	Formyl_trans_C	UniProtKB/TrEMBL
	Formyl_trans_C_sf	UniProtKB/TrEMBL
	Formyl_transf_N	UniProtKB/TrEMBL
	Formyl_transf_N_sf	UniProtKB/TrEMBL
	Formyl_transferase-like_C_sf	UniProtKB/TrEMBL
	GART_AS	UniProtKB/TrEMBL
	PP-bd_ACP	UniProtKB/TrEMBL
	Ppantetheine_attach_site	UniProtKB/TrEMBL
KEGG Report	cfa:474534	UniProtKB/TrEMBL
NCBI Gene	ALDH1L2	ENTREZGENE
PANTHER	ALDEHYDE DEHYDROGENASE-RELATED	UniProtKB/TrEMBL
	MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE	UniProtKB/TrEMBL
Pfam	Aldedh	UniProtKB/TrEMBL
	Formyl_trans_C	UniProtKB/TrEMBL
	Formyl_trans_N	UniProtKB/TrEMBL
	PP-binding	UniProtKB/TrEMBL
PIRSF	10-FTHFDH	UniProtKB/TrEMBL
PROSITE	ALDEHYDE_DEHYDR_CYS	UniProtKB/TrEMBL
	ALDEHYDE_DEHYDR_GLU	UniProtKB/TrEMBL
	CARRIER	UniProtKB/TrEMBL
	GART	UniProtKB/TrEMBL
	PHOSPHOPANTETHEINE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47336	UniProtKB/TrEMBL
	SSF50486	UniProtKB/TrEMBL
	SSF53328	UniProtKB/TrEMBL
	SSF53720	UniProtKB/TrEMBL
UniProt	A0A8C0PNX7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0YT63	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0YTD5_CANLF	UniProtKB/TrEMBL
	A0A8I3N0G4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0N521	ENTREZGENE
UniProt Secondary	A0A8P0N521	UniProtKB/TrEMBL
VGNC ID	VGNC:37785	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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