MGAT4B (alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MGAT4B (alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B) Canis lupus familiaris
Analyze
Symbol: MGAT4B
Name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
RGD ID: 12150297
Description: ENCODES a protein that exhibits acetylglucosaminyltransferase activity (inferred); alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (inferred); glycosyltransferase activity (inferred); INVOLVED IN protein N-linked glycosylation (ortholog); ASSOCIATED WITH Ehlers-Danlos syndrome dermatosparaxis type (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis 1 (ortholog); Sotos syndrome (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum-Golgi intermediate compartment (inferred); Golgi stack (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,883,440 - 1,892,949 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,882,976 - 1,913,145 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,006,767 - 2,016,345 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0111,857,841 - 1,867,419 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl111,857,910 - 1,867,097 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1111,829,438 - 1,839,016 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0111,908,604 - 1,918,183 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,148,828 - 2,158,407 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MGAT4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,883,440 - 1,892,949 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,882,976 - 1,913,145 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,006,767 - 2,016,345 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0111,857,841 - 1,867,419 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl111,857,910 - 1,867,097 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1111,829,438 - 1,839,016 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0111,908,604 - 1,918,183 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,148,828 - 2,158,407 (+)NCBIUU_Cfam_GSD_1.0
MGAT4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,797,597 - 179,806,866 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,797,597 - 179,806,952 (-)EnsemblGRCh38hg38GRCh38
GRCh375179,224,597 - 179,233,866 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,156,711 - 179,166,547 (-)NCBINCBI36Build 36hg18NCBI36
Celera5174,849,754 - 174,859,109 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,950,773 - 173,959,800 (-)NCBIHuRef
CHM1_15178,657,002 - 178,666,353 (-)NCBICHM1_1
T2T-CHM13v2.05180,352,793 - 180,362,062 (-)NCBIT2T-CHM13v2.0
Mgat4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,116,162 - 50,125,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,101,717 - 50,125,930 (+)EnsemblGRCm39 Ensembl
GRCm381150,225,335 - 50,235,103 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,210,890 - 50,235,103 (+)EnsemblGRCm38mm10GRCm38
MGSCv371150,038,837 - 50,048,605 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,069,056 - 50,078,073 (+)NCBIMGSCv36mm8
Celera1154,785,912 - 54,795,681 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.37NCBI
Mgat4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,049,421 - 35,060,307 (+)NCBIGRCr8
mRatBN7.21034,548,918 - 34,559,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,549,433 - 34,559,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,224,777 - 39,234,576 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,764,029 - 7,773,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,218,449 - 34,228,248 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,726,501 - 35,736,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,726,544 - 35,736,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,487,146 - 35,496,941 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,775,757 - 35,785,551 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1033,898,684 - 33,908,479 (+)NCBICelera
Cytogenetic Map10q22NCBI
Mgat4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955408784,890 - 788,030 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955408784,826 - 788,464 (+)NCBIChiLan1.0ChiLan1.0
MGAT4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24174,740,619 - 174,749,656 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,880,158 - 172,889,443 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,951,892 - 174,961,201 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,262,103 - 182,266,745 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,262,583 - 182,267,676 (-)Ensemblpanpan1.1panPan2
Mgat4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213119,754,693 - 119,764,652 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936739964,470 - 974,449 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936739964,476 - 974,429 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGAT4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl278,783,785 - 78,798,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1278,783,775 - 78,798,425 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2280,350,067 - 80,364,474 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MGAT4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12381,527,419 - 81,536,715 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2381,526,533 - 81,536,708 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607512,904,490 - 12,913,802 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgat4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473342,673,710 - 42,681,073 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473342,673,286 - 42,681,080 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MGAT4B
54 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 2 12 10 6
Low 4 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000000562   ⟹   ENSCAFP00000000511
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl111,882,976 - 1,892,684 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000064381   ⟹   ENSCAFP00000055005
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl111,882,976 - 1,892,953 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000065421   ⟹   ENSCAFP00000043433
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl111,882,976 - 1,913,145 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000068901   ⟹   ENSCAFP00000051640
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl111,882,976 - 1,892,953 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845013641   ⟹   ENSCAFP00845010592
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl111,857,910 - 1,867,097 (+)Ensembl
RefSeq Acc Id: XM_038489724   ⟹   XP_038345652
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1111,829,438 - 1,839,016 (+)NCBI
RefSeq Acc Id: XM_038551742   ⟹   XP_038407670
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0112,148,828 - 2,158,407 (+)NCBI
RefSeq Acc Id: XM_038615631   ⟹   XP_038471559
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0111,908,604 - 1,918,183 (+)NCBI
RefSeq Acc Id: XM_038681124   ⟹   XP_038537052
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0111,857,841 - 1,867,419 (+)NCBI
RefSeq Acc Id: XM_538579   ⟹   XP_538579
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1111,883,440 - 1,892,949 (+)NCBI
Dog10K_Boxer_Tasha112,006,767 - 2,016,345 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_538579   ⟸   XM_538579
- UniProtKB: A0A8C0JQB8 (UniProtKB/TrEMBL),   A0A8C0S0F8 (UniProtKB/TrEMBL),   A0A8I3RVK4 (UniProtKB/TrEMBL),   A0A8C0QU28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000051640   ⟸   ENSCAFT00000068901
RefSeq Acc Id: ENSCAFP00000055005   ⟸   ENSCAFT00000064381
RefSeq Acc Id: ENSCAFP00000000511   ⟸   ENSCAFT00000000562
RefSeq Acc Id: ENSCAFP00000043433   ⟸   ENSCAFT00000065421
RefSeq Acc Id: XP_038345652   ⟸   XM_038489724
RefSeq Acc Id: XP_038471559   ⟸   XM_038615631
RefSeq Acc Id: XP_038537052   ⟸   XM_038681124
- UniProtKB: A0A8C0JQB8 (UniProtKB/TrEMBL),   A0A8C0S0F8 (UniProtKB/TrEMBL),   A0A8I3RVK4 (UniProtKB/TrEMBL),   A0A8C0QU28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407670   ⟸   XM_038551742
- UniProtKB: A0A8C0JQB8 (UniProtKB/TrEMBL),   A0A8C0QU28 (UniProtKB/TrEMBL),   A0A8C0S0F8 (UniProtKB/TrEMBL),   A0A8I3RVK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845010592   ⟸   ENSCAFT00845013641

Promoters
RGD ID:13685126
Promoter ID:EPDNEW_C3193
Type:initiation region
Name:MGAT4B_1
Description:mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase,isozyme B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1111,883,182 - 1,883,242EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000355 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006844 UniProtKB/TrEMBL
  ENSCAFG00040008150 UniProtKB/TrEMBL
  ENSCAFG00845007711 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000000562.5 UniProtKB/TrEMBL
  ENSCAFT00030012611.1 UniProtKB/TrEMBL
  ENSCAFT00040015311.1 UniProtKB/TrEMBL
  ENSCAFT00845013641 ENTREZGENE
  ENSCAFT00845013641.1 UniProtKB/TrEMBL
InterPro Glyco_transf_54 UniProtKB/TrEMBL
KEGG Report cfa:481458 UniProtKB/TrEMBL
NCBI Gene MGAT4B ENTREZGENE
PANTHER ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B UniProtKB/TrEMBL
  PTHR12062 UniProtKB/TrEMBL
Pfam Glyco_transf_54 UniProtKB/TrEMBL
UniProt A0A8C0JQB8 ENTREZGENE
  A0A8C0QU28 ENTREZGENE
  A0A8C0S0F8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RVK4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:51745 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-26 MGAT4B  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B    mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B  Symbol and/or name change 5135510 APPROVED