MPST (mercaptopyruvate sulfurtransferase) - Rat Genome Database

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Gene: MPST (mercaptopyruvate sulfurtransferase) Canis lupus familiaris
Analyze
Symbol: MPST
Name: mercaptopyruvate sulfurtransferase
RGD ID: 12150076
Description: ENCODES a protein that exhibits identical protein binding (ortholog); thiosulfate sulfurtransferase activity (ortholog); INVOLVED IN kidney development (ortholog); liver development (ortholog); spinal cord development (ortholog); PARTICIPATES IN cysteine metabolic pathway; mercaptolactate-cysteine disulfiduria pathway; ocular nonnephropathic cystinosis pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); melanoma (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-mercaptopyruvate sulfurtransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,465,007 - 27,469,788 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,443,865 - 27,469,554 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,419,572 - 27,427,730 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,257,080 - 28,265,242 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,254,100 - 28,265,176 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,978,667 - 27,986,827 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,287,244 - 28,295,406 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,465,170 - 28,473,346 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MPST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,465,007 - 27,469,788 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,443,865 - 27,469,554 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,419,572 - 27,427,730 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,257,080 - 28,265,242 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,254,100 - 28,265,176 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,978,667 - 27,986,827 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,287,244 - 28,295,406 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,465,170 - 28,473,346 (-)NCBIUU_Cfam_GSD_1.0
MPST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,019,742 - 37,029,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,019,635 - 37,029,821 (+)EnsemblGRCh38hg38GRCh38
GRCh372237,415,783 - 37,425,856 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,745,648 - 35,755,809 (+)NCBINCBI36Build 36hg18NCBI36
Build 342235,740,290 - 35,750,363NCBI
Celera2221,217,038 - 21,227,199 (+)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2220,380,914 - 20,391,094 (+)NCBIHuRef
CHM1_12237,375,175 - 37,385,355 (+)NCBICHM1_1
T2T-CHM13v2.02237,479,341 - 37,489,414 (+)NCBIT2T-CHM13v2.0
Mpst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,290,918 - 78,298,213 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,290,616 - 78,298,213 (+)EnsemblGRCm39 Ensembl
GRCm381578,406,712 - 78,414,015 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,406,416 - 78,414,013 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,237,142 - 78,244,445 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,234,359 - 78,241,268 (+)NCBIMGSCv36mm8
Celera1579,869,406 - 79,876,711 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.47NCBI
Mpst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,836,079 - 111,843,651 (+)NCBIGRCr8
mRatBN7.27109,955,581 - 109,963,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,955,675 - 109,963,141 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,705,344 - 111,712,997 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07113,928,877 - 113,936,530 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07113,897,575 - 113,905,031 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,626,636 - 119,631,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,626,637 - 119,631,425 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,617,311 - 119,621,992 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,359,466 - 116,364,146 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,393,694 - 116,398,377 (+)NCBI
Celera7106,296,353 - 106,301,034 (+)NCBICelera
Cytogenetic Map7q34NCBI
Mpst
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,538,648 - 23,547,120 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,538,648 - 23,543,132 (+)NCBIChiLan1.0ChiLan1.0
MPST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22346,876,544 - 46,886,778 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12249,565,112 - 49,575,337 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02217,933,995 - 17,944,196 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,770,203 - 35,780,250 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,770,209 - 35,780,250 (+)Ensemblpanpan1.1panPan2
Mpst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,862,881 - 10,866,510 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,873,176 - 3,876,706 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,873,295 - 3,876,895 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,739,197 - 10,749,731 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,739,179 - 10,749,826 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.258,338,529 - 8,345,210 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MPST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11919,724,780 - 19,735,503 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1919,724,809 - 19,735,194 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045106,127,100 - 106,137,854 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,756,634 - 10,764,936 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,756,634 - 10,764,950 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MPST
65 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000002361   ⟹   ENSCAFP00000002183
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1027,443,865 - 27,469,554 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845013822   ⟹   ENSCAFP00845010724
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1028,254,100 - 28,265,176 (-)Ensembl
RefSeq Acc Id: XM_038488702   ⟹   XP_038344630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11027,978,667 - 27,986,827 (-)NCBI
RefSeq Acc Id: XM_038550666   ⟹   XP_038406594
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01028,465,170 - 28,473,346 (-)NCBI
RefSeq Acc Id: XM_038614597   ⟹   XP_038470525
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01028,287,244 - 28,295,406 (-)NCBI
RefSeq Acc Id: XM_038640439   ⟹   XP_038496367
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1027,419,572 - 27,427,730 (-)NCBI
RefSeq Acc Id: XM_038679957   ⟹   XP_038535885
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01028,257,080 - 28,265,242 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000002183   ⟸   ENSCAFT00000002361
RefSeq Acc Id: XP_038344630   ⟸   XM_038488702
RefSeq Acc Id: XP_038470525   ⟸   XM_038614597
RefSeq Acc Id: XP_038535885   ⟸   XM_038679957
- UniProtKB: A0A8C0JV07 (UniProtKB/TrEMBL),   A0A8C0S7N4 (UniProtKB/TrEMBL),   A0A8I3N772 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038496367   ⟸   XM_038640439
- UniProtKB: A0A8C0JV07 (UniProtKB/TrEMBL),   A0A8C0S7N4 (UniProtKB/TrEMBL),   A0A8I3N772 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406594   ⟸   XM_038550666
RefSeq Acc Id: ENSCAFP00845010724   ⟸   ENSCAFT00845013822
Protein Domains
Rhodanese

Promoters
RGD ID:13684987
Promoter ID:EPDNEW_C3056
Type:initiation region
Name:MPST_1
Description:mercaptopyruvate sulfurtransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11027,469,588 - 27,469,648EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001514 Ensembl
  ENSCAFG00000058214 UniProtKB/TrEMBL
  ENSCAFG00040010706 UniProtKB/TrEMBL
  ENSCAFG00845007861 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000094775.1 UniProtKB/TrEMBL
  ENSCAFT00040019793.1 UniProtKB/TrEMBL
  ENSCAFT00845013822 ENTREZGENE
  ENSCAFT00845013822.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/TrEMBL
InterPro Rhodanese-like_dom UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
  Thiosulphate_STrfase_CS UniProtKB/TrEMBL
  TST/MPST-like UniProtKB/TrEMBL
NCBI Gene MPST ENTREZGENE
PANTHER 3-MERCAPTOPYRUVATE SULFURTRANSFERASE UniProtKB/TrEMBL
  PTHR11364 UniProtKB/TrEMBL
Pfam Rhodanese UniProtKB/TrEMBL
PROSITE RHODANESE_1 UniProtKB/TrEMBL
  RHODANESE_2 UniProtKB/TrEMBL
  RHODANESE_3 UniProtKB/TrEMBL
SMART RHOD UniProtKB/TrEMBL
Superfamily-SCOP SSF52821 UniProtKB/TrEMBL
UniProt A0A8C0JV07 ENTREZGENE
  A0A8C0S7N4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N772 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43351 ENTREZGENE