HOXD11 (homeobox D11) - Rat Genome Database

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Gene: HOXD11 (homeobox D11) Canis lupus familiaris
Analyze
Symbol: HOXD11
Name: homeobox D11
RGD ID: 12128959
Description: ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); cartilage development involved in endochondral bone morphogenesis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); bone development disease (ortholog); Breast Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein Hox-D11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13619,913,064 - 19,926,868 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3619,914,431 - 19,916,766 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3619,921,364 - 19,929,032 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03620,052,553 - 20,060,228 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13620,129,998 - 20,134,442 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03620,130,689 - 20,135,144 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03620,239,278 - 20,246,796 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HOXD11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13619,913,064 - 19,926,868 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3619,914,431 - 19,916,766 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3619,921,364 - 19,929,032 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03620,052,553 - 20,060,228 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13620,129,998 - 20,134,442 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03620,130,689 - 20,135,144 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03620,239,278 - 20,246,796 (+)NCBIUU_Cfam_GSD_1.0
HOXD11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382176,107,280 - 176,115,679 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2176,104,216 - 176,109,754 (+)EnsemblGRCh38hg38GRCh38
GRCh372176,972,008 - 176,974,482 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362176,680,330 - 176,682,562 (+)NCBINCBI36Build 36hg18NCBI36
Build 342176,797,590 - 176,799,823NCBI
Celera2170,581,234 - 170,583,461 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2168,849,568 - 168,851,540 (+)NCBIHuRef
CHM1_12176,977,935 - 176,980,184 (+)NCBICHM1_1
T2T-CHM13v2.02176,595,402 - 176,599,952 (+)NCBIT2T-CHM13v2.0
Hoxd11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39274,509,902 - 74,517,360 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl274,509,901 - 74,517,360 (+)EnsemblGRCm39 Ensembl
GRCm38274,679,558 - 74,687,016 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl274,679,557 - 74,687,016 (+)EnsemblGRCm38mm10GRCm38
MGSCv37274,520,450 - 74,522,195 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36274,483,232 - 74,484,977 (+)NCBIMGSCv36mm8
Celera276,352,501 - 76,354,246 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.13NCBI
Hoxd11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8379,992,394 - 79,994,688 (+)NCBIGRCr8
mRatBN7.2359,584,840 - 59,587,257 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl359,585,039 - 59,586,783 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0361,604,256 - 61,606,874 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl361,604,672 - 61,606,400 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0368,071,282 - 68,076,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera359,104,507 - 59,109,071 (+)NCBICelera
Cytogenetic Map3q23NCBI
Hoxd11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540320,541,870 - 20,556,574 (-)NCBIChiLan1.0ChiLan1.0
HOXD11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21378,774,821 - 78,780,697 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B78,789,797 - 78,792,163 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B63,386,806 - 63,398,777 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B181,095,347 - 181,098,680 (+)NCBIpanpan1.1PanPan1.1panPan2
HOXD11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1581,908,460 - 81,911,282 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11581,906,654 - 81,910,765 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21591,374,469 - 91,377,543 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXD11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11061,681,474 - 61,693,974 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1061,682,400 - 61,684,168 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040137,925,780 - 137,928,157 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in HOXD11
132 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 4
Below cutoff 1 4 13 1 4 1 4 6 8 8 7 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000021317   ⟹   ENSCAFP00000019793
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3619,914,431 - 19,916,766 (+)Ensembl
RefSeq Acc Id: XM_014110871   ⟹   XP_013966346
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13619,913,064 - 19,917,688 (+)NCBI
Dog10K_Boxer_Tasha3619,924,588 - 19,929,032 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038447146   ⟹   XP_038303074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03620,055,777 - 20,060,228 (+)NCBI
RefSeq Acc Id: XM_038521226   ⟹   XP_038377154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13620,129,998 - 20,134,442 (+)NCBI
RefSeq Acc Id: XM_038584931   ⟹   XP_038440859
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03620,242,502 - 20,246,796 (+)NCBI
RefSeq Acc Id: XM_038649345   ⟹   XP_038505273
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03620,130,689 - 20,135,144 (+)NCBI
RefSeq Acc Id: XR_005307875
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03620,052,553 - 20,057,750 (+)NCBI
RefSeq Acc Id: XR_005318237
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3619,921,364 - 19,926,555 (+)NCBI
RefSeq Acc Id: XR_005384768
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03620,239,278 - 20,244,479 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013966346   ⟸   XM_014110871
- UniProtKB: A0A8C0QW59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000019793   ⟸   ENSCAFT00000021317
RefSeq Acc Id: XP_038377154   ⟸   XM_038521226
RefSeq Acc Id: XP_038505273   ⟸   XM_038649345
RefSeq Acc Id: XP_038303074   ⟸   XM_038447146
- UniProtKB: A0A8C0QW59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440859   ⟸   XM_038584931


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013436 Ensembl
NCBI Gene HOXD11 ENTREZGENE
UniProt A0A8C0QW59 ENTREZGENE
VGNC ID VGNC:41763 ENTREZGENE