CDH19 (cadherin 19) - Rat Genome Database

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Gene: CDH19 (cadherin 19) Canis lupus familiaris
Analyze
Symbol: CDH19
Name: cadherin 19
RGD ID: 12124747
Description: ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (inferred); cell adhesion (inferred); ASSOCIATED WITH chromosome 18q deletion syndrome (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN adherens junction (inferred); catenin complex (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cadherin-19
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,074,216 - 11,168,816 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,074,305 - 11,165,626 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,099,395 - 12,193,906 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0110,925,758 - 11,020,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl110,925,808 - 11,020,334 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1110,957,834 - 11,052,271 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0110,899,197 - 10,994,210 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0111,144,592 - 11,239,098 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDH19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,074,216 - 11,168,816 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,074,305 - 11,165,626 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,099,395 - 12,193,906 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0110,925,758 - 11,020,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl110,925,808 - 11,020,334 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1110,957,834 - 11,052,271 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0110,899,197 - 10,994,210 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0111,144,592 - 11,239,098 (+)NCBIUU_Cfam_GSD_1.0
CDH19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381866,501,083 - 66,604,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1866,501,083 - 66,604,138 (-)EnsemblGRCh38hg38GRCh38
GRCh371864,168,320 - 64,271,327 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361862,322,301 - 62,422,196 (-)NCBINCBI36Build 36hg18NCBI36
Build 341862,322,300 - 62,422,196NCBI
Celera1860,889,278 - 60,989,190 (-)NCBICelera
Cytogenetic Map18q22.1NCBI
HuRef1860,868,984 - 60,971,955 (-)NCBIHuRef
CHM1_11864,163,645 - 64,266,628 (-)NCBICHM1_1
T2T-CHM13v2.01866,699,077 - 66,802,147 (-)NCBIT2T-CHM13v2.0
Cdh19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391110,811,802 - 110,905,331 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1110,816,056 - 110,905,314 (-)EnsemblGRCm39 Ensembl
GRCm381110,888,002 - 110,977,601 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1110,888,326 - 110,977,584 (-)EnsemblGRCm38mm10GRCm38
MGSCv371112,785,772 - 112,873,949 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361112,716,742 - 112,804,919 (-)NCBIMGSCv36mm8
Celera1113,646,024 - 113,729,311 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map150.78NCBI
Cdh19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81328,450,361 - 28,561,932 (-)NCBIGRCr8
mRatBN7.21327,935,915 - 28,047,490 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1327,936,668 - 28,019,310 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1328,329,664 - 28,411,052 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01329,614,185 - 29,695,576 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01328,262,267 - 28,343,715 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01332,344,954 - 32,469,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1332,344,966 - 32,427,177 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01337,482,078 - 37,607,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41318,148,715 - 18,230,353 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11318,151,455 - 18,233,094 (-)NCBI
Celera1327,679,457 - 27,760,138 (-)NCBICelera
Cytogenetic Map13q11NCBI
Cdh19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540250,112,516 - 50,213,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540250,110,907 - 50,213,882 (-)NCBIChiLan1.0ChiLan1.0
CDH19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21784,005,355 - 84,107,699 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11869,697,969 - 69,800,300 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01859,852,350 - 59,954,744 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11863,156,263 - 63,258,546 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1863,156,263 - 63,258,767 (-)Ensemblpanpan1.1panPan2
Cdh19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494424,452,037 - 24,483,848 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049381822,674 - 13,253 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1155,669,420 - 155,758,548 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11155,669,361 - 155,758,550 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21172,916,611 - 173,006,358 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDH19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11813,155,504 - 13,256,781 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1813,187,487 - 13,256,691 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606012,513,300 - 12,621,161 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479212,635,240 - 12,752,439 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479212,633,803 - 12,752,267 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDH19
1340 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1
Low 4 5 10 6 6 2 6 7 6
Below cutoff 12 6 6 4 6 8 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000000075   ⟹   ENSCAFP00000000059
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl111,074,305 - 11,165,626 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000084112   ⟹   ENSCAFP00000045899
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl111,074,305 - 11,165,150 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845003434   ⟹   ENSCAFP00845002723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl110,925,808 - 11,020,334 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845003444   ⟹   ENSCAFP00845002730
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl110,925,815 - 11,020,332 (+)Ensembl
RefSeq Acc Id: XM_005615336   ⟹   XP_005615393
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1111,074,216 - 11,168,816 (+)NCBI
Dog10K_Boxer_Tasha112,099,395 - 12,193,906 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038465231   ⟹   XP_038321159
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1110,957,834 - 11,052,271 (+)NCBI
RefSeq Acc Id: XM_038525831   ⟹   XP_038381759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0111,144,593 - 11,239,098 (+)NCBI
RefSeq Acc Id: XM_038525832   ⟹   XP_038381760
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0111,144,592 - 11,239,098 (+)NCBI
RefSeq Acc Id: XM_038590140   ⟹   XP_038446068
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0110,899,198 - 10,994,210 (+)NCBI
RefSeq Acc Id: XM_038590141   ⟹   XP_038446069
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0110,899,197 - 10,994,210 (+)NCBI
RefSeq Acc Id: XM_038653969   ⟹   XP_038509897
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0110,925,759 - 11,020,339 (+)NCBI
RefSeq Acc Id: XM_038653970   ⟹   XP_038509898
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0110,925,758 - 11,020,339 (+)NCBI
RefSeq Acc Id: XM_541068   ⟹   XP_541068
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1111,074,216 - 11,168,816 (+)NCBI
Dog10K_Boxer_Tasha112,099,396 - 12,193,906 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_541068   ⟸   XM_541068
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MEQ3 (UniProtKB/TrEMBL),   A0A8P0S5Y5 (UniProtKB/TrEMBL),   A0A8C0NB26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005615393   ⟸   XM_005615336
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NB26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000045899   ⟸   ENSCAFT00000084112
RefSeq Acc Id: ENSCAFP00000000059   ⟸   ENSCAFT00000000075
RefSeq Acc Id: XP_038321159   ⟸   XM_038465231
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038446069   ⟸   XM_038590141
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038446068   ⟸   XM_038590140
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038509898   ⟸   XM_038653970
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NB26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038509897   ⟸   XM_038653969
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MEQ3 (UniProtKB/TrEMBL),   A0A8P0S5Y5 (UniProtKB/TrEMBL),   A0A8C0NB26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381760   ⟸   XM_038525832
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NB26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381759   ⟸   XM_038525831
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NB26 (UniProtKB/TrEMBL),   A0A8I3MEQ3 (UniProtKB/TrEMBL),   A0A8P0S5Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845002730   ⟸   ENSCAFT00845003444
RefSeq Acc Id: ENSCAFP00845002723   ⟸   ENSCAFT00845003434
Protein Domains
Cadherin

Promoters
RGD ID:13681946
Promoter ID:EPDNEW_C14
Type:single initiation site
Name:CDH19_1
Description:cadherin 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1111,074,278 - 11,074,338EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000052 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014803 UniProtKB/TrEMBL
  ENSCAFG00845001959 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000000075.5 UniProtKB/TrEMBL
  ENSCAFT00000084112.2 UniProtKB/TrEMBL
  ENSCAFT00030027639.1 UniProtKB/TrEMBL
  ENSCAFT00845003434.1 UniProtKB/TrEMBL
  ENSCAFT00845003444 ENTREZGENE
  ENSCAFT00845003444.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Catenin-bd_sf UniProtKB/TrEMBL
NCBI Gene CDH19 ENTREZGENE
PANTHER CADHERIN-19 UniProtKB/TrEMBL
  PTHR24027 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
UniProt A0A8C0NB26 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MEQ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MEZ8_CANLF UniProtKB/TrEMBL
  A0A8P0S5Y5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SZ29_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:39027 ENTREZGENE