UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) - Rat Genome Database

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Gene: UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) Canis lupus familiaris
Analyze
Symbol: UQCRFS1
Name: ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
RGD ID: 12108200
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN mitochondrial respiratory chain complex III assembly (ortholog); respiratory electron transport chain (ortholog); response to hormone (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); Experimental Seizures (ortholog); lactic acidosis (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrial respiratory chain complex III (ortholog); mitochondrial respiratory chain complex IV (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytochrome b-c1 complex subunit Rieske, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,035,193 - 122,038,032 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,035,197 - 122,037,759 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,336,791 - 121,339,788 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01122,668,156 - 122,671,153 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,668,169 - 122,672,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,243,598 - 122,246,656 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,850,901 - 121,854,019 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,914,720 - 122,918,053 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UQCRFS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,035,193 - 122,038,032 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,035,197 - 122,037,759 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,336,791 - 121,339,788 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01122,668,156 - 122,671,153 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,668,169 - 122,672,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,243,598 - 122,246,656 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,850,901 - 121,854,019 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,914,720 - 122,918,053 (+)NCBIUU_Cfam_GSD_1.0
UQCRFS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381929,205,320 - 29,213,151 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1929,205,320 - 29,213,151 (-)EnsemblGRCh38hg38GRCh38
GRCh371929,696,227 - 29,704,058 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361934,390,007 - 34,395,954 (-)NCBINCBI36Build 36hg18NCBI36
Build 341934,390,006 - 34,395,954NCBI
Celera1926,400,450 - 26,406,405 (-)NCBICelera
Cytogenetic Map19q12NCBI
HuRef1926,215,131 - 26,221,101 (-)NCBIHuRef
CHM1_11929,699,125 - 29,705,094 (-)NCBICHM1_1
T2T-CHM13v2.01931,736,436 - 31,744,253 (-)NCBIT2T-CHM13v2.0
Uqcrfs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391330,724,295 - 30,729,299 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1330,724,291 - 30,729,345 (-)EnsemblGRCm39 Ensembl
GRCm381330,540,312 - 30,545,316 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1330,540,308 - 30,545,362 (-)EnsemblGRCm38mm10GRCm38
MGSCv371330,632,181 - 30,637,185 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361330,547,777 - 30,552,785 (-)NCBIMGSCv36mm8
Celera1330,754,531 - 30,759,562 (-)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.23NCBI
Uqcrfs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81734,173,787 - 34,190,952 (+)NCBIGRCr8
mRatBN7.21733,977,908 - 33,982,478 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1733,977,921 - 33,982,479 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1733,816,701 - 33,820,962 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01735,420,584 - 35,424,845 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01733,812,512 - 33,816,773 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01735,677,984 - 35,682,262 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1735,677,984 - 35,682,259 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01736,991,588 - 36,995,866 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41740,429,806 - 40,434,083 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11740,432,755 - 40,436,859 (+)NCBI
Celera1733,517,087 - 33,521,364 (+)NCBICelera
Cytogenetic Map17p12NCBI
LOC102014998
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554688,331,153 - 8,338,628 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554688,331,153 - 8,338,628 (+)NCBIChiLan1.0ChiLan1.0
LOC100974890
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22035,192,052 - 35,197,971 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11937,188,573 - 37,194,492 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01926,139,335 - 26,145,231 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11934,905,765 - 34,911,712 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1934,905,765 - 34,911,712 (-)Ensemblpanpan1.1panPan2
LOC101959727
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093495,595,723 - 5,600,927 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365706,044,969 - 6,051,046 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100522678
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl639,364,890 - 39,373,872 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1639,366,761 - 39,373,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2634,525,752 - 34,530,705 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234417
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1624,293,640 - 24,298,983 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl624,293,920 - 24,299,043 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660731,814,696 - 1,820,587 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101708594
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247944,430,723 - 4,435,457 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247944,428,339 - 4,435,363 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UQCRFS1
69 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 5 2
Medium 5 22 6 6 6 6 4 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000012203   ⟹   ENSCAFP00000011310
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1122,035,197 - 122,037,759 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845002200   ⟹   ENSCAFP00845001737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1122,668,169 - 122,672,983 (+)Ensembl
RefSeq Acc Id: XM_038468747   ⟹   XP_038324675
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11122,243,598 - 122,246,656 (+)NCBI
RefSeq Acc Id: XM_038529554   ⟹   XP_038385482
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01122,914,720 - 122,918,053 (+)NCBI
RefSeq Acc Id: XM_038593798   ⟹   XP_038449726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01121,850,901 - 121,854,019 (+)NCBI
RefSeq Acc Id: XM_038657684   ⟹   XP_038513612
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01122,668,156 - 122,671,153 (+)NCBI
RefSeq Acc Id: XM_533711   ⟹   XP_533711
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11122,035,193 - 122,038,032 (+)NCBI
Dog10K_Boxer_Tasha1121,336,791 - 121,339,788 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_533711   ⟸   XM_533711
- UniProtKB: A0A8C0R4F6 (UniProtKB/TrEMBL),   A0A8C0R971 (UniProtKB/TrEMBL),   A0A8I3MI67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000011310   ⟸   ENSCAFT00000012203
RefSeq Acc Id: XP_038324675   ⟸   XM_038468747
RefSeq Acc Id: XP_038449726   ⟸   XM_038593798
RefSeq Acc Id: XP_038513612   ⟸   XM_038657684
- UniProtKB: A0A8C0R4F6 (UniProtKB/TrEMBL),   A0A8C0R971 (UniProtKB/TrEMBL),   A0A8I3MI67 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038385482   ⟸   XM_038529554
- UniProtKB: A0A8C0R4F6 (UniProtKB/TrEMBL),   A0A8C0R971 (UniProtKB/TrEMBL),   A0A8I3MI67 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001737   ⟸   ENSCAFT00845002200
Protein Domains
Rieske

Promoters
RGD ID:13682360
Promoter ID:EPDNEW_C430
Type:initiation region
Name:UQCRFS1_1
Description:ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11122,035,209 - 122,035,269EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007636 Ensembl
  ENSCAFG00000058483 UniProtKB/TrEMBL
  ENSCAFG00030000035 UniProtKB/TrEMBL
  ENSCAFG00845001274 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000097092.1 UniProtKB/TrEMBL
  ENSCAFT00030000040.1 UniProtKB/TrEMBL
  ENSCAFT00845002200 ENTREZGENE
  ENSCAFT00845002200.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.270 UniProtKB/TrEMBL
  2.102.10.10 UniProtKB/TrEMBL
InterPro bc1_Rieske_TM_sf UniProtKB/TrEMBL
  Globular_prot_asu/bsu UniProtKB/TrEMBL
  Rieske_2Fe-2S UniProtKB/TrEMBL
  Rieske_2Fe-2S_sf UniProtKB/TrEMBL
  Rieske_Fe-S_prot UniProtKB/TrEMBL
  Rieske_Fe-S_prot_C UniProtKB/TrEMBL
  Rieske_TM UniProtKB/TrEMBL
  Ubiqinol_cyt_c_Rdtase_N UniProtKB/TrEMBL
  Ubiquinol_cyt_c_Rdtase_Fe-S-su UniProtKB/TrEMBL
KEGG Report cfa:476503 UniProtKB/TrEMBL
NCBI Gene UQCRFS1 ENTREZGENE
PANTHER CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED UniProtKB/TrEMBL
  PTHR10134 UniProtKB/TrEMBL
Pfam Rieske UniProtKB/TrEMBL
  Ubiq-Cytc-red_N UniProtKB/TrEMBL
  UCR_TM UniProtKB/TrEMBL
PRINTS RIESKE UniProtKB/TrEMBL
PROSITE RIESKE UniProtKB/TrEMBL
Superfamily-SCOP ISP transmembrane anchor UniProtKB/TrEMBL
  SSF50022 UniProtKB/TrEMBL
  SSF56568 UniProtKB/TrEMBL
UniProt A0A8C0R4F6 ENTREZGENE
  A0A8C0R971 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MI67 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:53998 ENTREZGENE