WDR49 (WD repeat domain 49) - Rat Genome Database

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Gene: WDR49 (WD repeat domain 49) Canis lupus familiaris
Analyze
Symbol: WDR49
Name: WD repeat domain 49
RGD ID: 12086136
Description: ENCODES a protein that exhibits calcium ion binding (inferred); ASSOCIATED WITH prostate cancer (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WD repeat-containing protein 49
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13432,362,006 - 32,490,180 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3432,363,257 - 32,489,588 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3441,437,883 - 41,571,373 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03432,444,588 - 32,569,304 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3432,442,421 - 32,569,582 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13432,380,958 - 32,514,511 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03432,350,111 - 32,474,970 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03432,613,027 - 32,746,637 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
WDR49
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13432,362,006 - 32,490,180 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3432,363,257 - 32,489,588 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3441,437,883 - 41,571,373 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03432,444,588 - 32,569,304 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3432,442,421 - 32,569,582 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13432,380,958 - 32,514,511 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03432,350,111 - 32,474,970 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03432,613,027 - 32,746,637 (-)NCBIUU_Cfam_GSD_1.0
WDR49
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383167,478,684 - 167,657,923 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3167,478,684 - 167,653,983 (-)EnsemblGRCh38hg38GRCh38
GRCh373167,196,472 - 167,375,711 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363168,679,166 - 168,853,983 (-)NCBINCBI36Build 36hg18NCBI36
Build 343168,679,173 - 168,853,991NCBI
Celera3165,595,023 - 165,769,739 (-)NCBICelera
Cytogenetic Map3q26.1NCBI
HuRef3164,566,706 - 164,741,365 (-)NCBIHuRef
CHM1_13167,158,739 - 167,333,549 (-)NCBICHM1_1
T2T-CHM13v2.03170,262,569 - 170,441,822 (-)NCBIT2T-CHM13v2.0
Wdr49
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39375,181,235 - 75,389,472 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl375,182,295 - 75,389,463 (-)EnsemblGRCm39 Ensembl
GRCm38375,273,928 - 75,482,165 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl375,274,988 - 75,482,156 (-)EnsemblGRCm38mm10GRCm38
MGSCv37375,078,910 - 75,255,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36375,360,914 - 75,567,616 (-)NCBIMGSCv36mm8
Celera375,356,332 - 75,546,887 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map333.75NCBI
Wdr49
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82162,349,030 - 162,563,117 (-)NCBIGRCr8
mRatBN7.22160,049,478 - 160,264,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2160,051,458 - 160,264,511 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02173,675,780 - 173,800,840 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2173,676,089 - 173,836,854 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02193,009,340 - 193,219,850 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42166,141,360 - 166,318,378 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2154,257,377 - 154,384,526 (-)NCBICelera
Cytogenetic Map2q32NCBI
Wdr49
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544816,701,241 - 16,840,180 (-)NCBIChiLan1.0ChiLan1.0
WDR49
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22165,372,262 - 165,554,324 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13165,376,989 - 165,559,050 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03164,492,444 - 164,679,218 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13172,550,188 - 172,731,283 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3172,550,015 - 172,730,794 (-)Ensemblpanpan1.1panPan2
Wdr49
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560298,769,467 - 98,904,900 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365934,717,043 - 4,851,710 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR49
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13106,348,219 - 106,492,808 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113106,348,216 - 106,492,792 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213114,910,270 - 115,069,959 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR49
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11521,778,500 - 21,967,551 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606330,623,067 - 30,807,150 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr49
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473045,450,817 - 45,630,205 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in WDR49
2139 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 6 12 4
Below cutoff 4 3 11 2 6 2 2 2 8 6 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000023111   ⟹   ENSCAFP00000021457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3432,365,559 - 32,489,588 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000093434   ⟹   ENSCAFP00000064372
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3432,363,257 - 32,453,421 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033400   ⟹   ENSCAFP00845026147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3432,442,421 - 32,569,582 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033520   ⟹   ENSCAFP00845026243
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3432,442,421 - 32,569,582 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033673   ⟹   ENSCAFP00845026363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3432,444,715 - 32,569,582 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033798   ⟹   ENSCAFP00845026449
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3432,484,588 - 32,569,582 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033872   ⟹   ENSCAFP00845026504
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3432,486,976 - 32,547,455 (-)Ensembl
RefSeq Acc Id: XM_014110456   ⟹   XP_013965931
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13432,365,346 - 32,490,180 (-)NCBI
Dog10K_Boxer_Tasha3441,437,883 - 41,571,373 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038445436   ⟹   XP_038301364
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03432,444,588 - 32,569,304 (-)NCBI
RefSeq Acc Id: XM_038520352   ⟹   XP_038376280
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13432,380,958 - 32,514,511 (-)NCBI
RefSeq Acc Id: XM_038583280   ⟹   XP_038439208
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03432,613,027 - 32,746,637 (-)NCBI
RefSeq Acc Id: XM_038647688   ⟹   XP_038503616
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03432,350,111 - 32,474,970 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013965931   ⟸   XM_014110456
- UniProtKB: A0A8P0NG49 (UniProtKB/TrEMBL),   A0A8C0NBV2 (UniProtKB/TrEMBL),   A0A8C0S174 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000064372   ⟸   ENSCAFT00000093434
RefSeq Acc Id: ENSCAFP00000021457   ⟸   ENSCAFT00000023111
RefSeq Acc Id: XP_038376280   ⟸   XM_038520352
RefSeq Acc Id: XP_038503616   ⟸   XM_038647688
RefSeq Acc Id: XP_038301364   ⟸   XM_038445436
- UniProtKB: A0A8I3P967 (UniProtKB/TrEMBL),   A0A8C0S174 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038439208   ⟸   XM_038583280
- UniProtKB: A0A8C0NBV2 (UniProtKB/TrEMBL),   A0A8C0S174 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845026243   ⟸   ENSCAFT00845033520
RefSeq Acc Id: ENSCAFP00845026147   ⟸   ENSCAFT00845033400
RefSeq Acc Id: ENSCAFP00845026363   ⟸   ENSCAFT00845033673
RefSeq Acc Id: ENSCAFP00845026504   ⟸   ENSCAFT00845033872
RefSeq Acc Id: ENSCAFP00845026449   ⟸   ENSCAFT00845033798
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014555 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013031 UniProtKB/TrEMBL
  ENSCAFG00040008759 UniProtKB/TrEMBL
  ENSCAFG00845018893 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000023111.5 UniProtKB/TrEMBL
  ENSCAFT00000093434.2 UniProtKB/TrEMBL
  ENSCAFT00000097072.1 UniProtKB/TrEMBL
  ENSCAFT00000102650.1 UniProtKB/TrEMBL
  ENSCAFT00000105126.1 UniProtKB/TrEMBL
  ENSCAFT00030024396.1 UniProtKB/TrEMBL
  ENSCAFT00040016547.1 UniProtKB/TrEMBL
  ENSCAFT00845033400.1 UniProtKB/TrEMBL
  ENSCAFT00845033520.1 UniProtKB/TrEMBL
  ENSCAFT00845033673 ENTREZGENE
  ENSCAFT00845033673.1 UniProtKB/TrEMBL
  ENSCAFT00845033798.1 UniProtKB/TrEMBL
  ENSCAFT00845033872.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:488144 UniProtKB/TrEMBL
NCBI Gene WDR49 ENTREZGENE
PANTHER WD REPEAT-CONTAINING PROTEIN 49 UniProtKB/TrEMBL
  WD40 REPEAT DOMAIN 95 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
  Tricorn protease domain 2 UniProtKB/TrEMBL
UniProt A0A8C0NBV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S174 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NXM5_CANLF UniProtKB/TrEMBL
  A0A8I3P3L6_CANLF UniProtKB/TrEMBL
  A0A8I3P883_CANLF UniProtKB/TrEMBL
  A0A8I3P967 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S3U7_CANLF UniProtKB/TrEMBL
  A0A8P0NG49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PHG5_CANLF UniProtKB/TrEMBL
  A0A8P0PQ13_CANLF UniProtKB/TrEMBL
  A0A8P0TFV7_CANLF UniProtKB/TrEMBL
  A0A8P0TI47_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:48372 ENTREZGENE