HAT1 (histone acetyltransferase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: HAT1 (histone acetyltransferase 1) Canis lupus familiaris
Analyze
Symbol: HAT1
Name: histone acetyltransferase 1
RGD ID: 12055703
Description: ENCODES a protein that exhibits acyltransferase activity (inferred); histone acetyltransferase activity (inferred); histone binding (inferred); INVOLVED IN response to nutrient (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Experimental Liver Neoplasms (ortholog); genetic disease (ortholog); split hand-foot malformation 5 (ortholog); FOUND IN chromatin (inferred); chromosome, telomeric region (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone acetyltransferase type B catalytic subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13616,310,269 - 16,378,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3616,310,710 - 16,378,017 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3616,319,567 - 16,386,968 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03616,431,302 - 16,499,107 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3616,431,842 - 16,499,102 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13616,518,419 - 16,587,009 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,518,212 - 16,587,468 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,621,373 - 16,690,546 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13616,310,269 - 16,378,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3616,310,710 - 16,378,017 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3616,319,567 - 16,386,968 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03616,431,302 - 16,499,107 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3616,431,842 - 16,499,102 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13616,518,419 - 16,587,009 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,518,212 - 16,587,468 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,621,373 - 16,690,546 (+)NCBIUU_Cfam_GSD_1.0
HAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382171,922,461 - 171,983,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2171,922,448 - 171,983,686 (+)EnsemblGRCh38hg38GRCh38
GRCh372172,778,971 - 172,848,600 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,487,204 - 172,556,846 (+)NCBINCBI36Build 36hg18NCBI36
Build 342172,604,481 - 172,674,045NCBI
Celera2166,395,980 - 166,464,808 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2164,663,728 - 164,732,503 (+)NCBIHuRef
CHM1_12172,786,060 - 172,855,754 (+)NCBICHM1_1
T2T-CHM13v2.02172,400,272 - 172,469,906 (+)NCBIT2T-CHM13v2.0
Hat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39271,219,604 - 71,271,966 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl271,219,302 - 71,271,966 (+)EnsemblGRCm39 Ensembl
GRCm38271,389,260 - 71,441,622 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,388,958 - 71,441,622 (+)EnsemblGRCm38mm10GRCm38
MGSCv37271,227,317 - 71,279,679 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36271,190,096 - 71,242,461 (+)NCBIMGSCv36mm8
Celera273,051,387 - 73,103,790 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map242.38NCBI
Hat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8376,624,442 - 76,672,701 (+)NCBIGRCr8
mRatBN7.2356,217,344 - 56,265,021 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl356,217,342 - 56,275,517 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx359,615,506 - 59,663,164 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0368,199,118 - 68,246,776 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0365,960,748 - 66,008,414 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0358,022,395 - 58,070,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl358,022,238 - 58,070,068 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0364,510,903 - 64,558,573 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4353,696,664 - 53,744,333 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1353,593,035 - 53,640,704 (+)NCBI
Celera355,764,984 - 55,812,590 (+)NCBICelera
Cytogenetic Map3q23NCBI
Hat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554493,025,461 - 3,066,919 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554493,026,194 - 3,070,448 (-)NCBIChiLan1.0ChiLan1.0
HAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21374,598,235 - 74,668,065 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B74,613,208 - 74,683,032 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B59,211,555 - 59,281,203 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B176,670,029 - 176,739,120 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B176,670,029 - 176,739,120 (+)Ensemblpanpan1.1panPan2
Hat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303133,515,135 - 133,599,141 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365092,105,845 - 2,153,198 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365092,105,866 - 2,153,089 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1578,022,207 - 78,079,608 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11578,022,147 - 78,079,669 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21587,491,263 - 87,550,047 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HAT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11057,412,916 - 57,482,682 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1057,412,910 - 57,482,351 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040142,067,033 - 142,136,064 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hat1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247879,346,741 - 9,403,700 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247879,343,124 - 9,402,630 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HAT1
1080 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 16 4 6 7 8 10 4
Low 1 5 6 6 2 6 6 5 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000020472   ⟹   ENSCAFP00000018999
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3616,310,710 - 16,378,017 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000061844   ⟹   ENSCAFP00000064392
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3616,313,028 - 16,378,017 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845050029   ⟹   ENSCAFP00845039227
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3616,431,842 - 16,499,102 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845050091   ⟹   ENSCAFP00845039276
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3616,431,842 - 16,498,828 (+)Ensembl
RefSeq Acc Id: XM_005640309   ⟹   XP_005640366
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13616,310,269 - 16,378,017 (+)NCBI
Dog10K_Boxer_Tasha3616,319,567 - 16,386,799 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038447064   ⟹   XP_038302992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03616,431,468 - 16,499,107 (+)NCBI
RefSeq Acc Id: XM_038447065   ⟹   XP_038302993
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03616,431,302 - 16,498,938 (+)NCBI
RefSeq Acc Id: XM_038521143   ⟹   XP_038377071
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13616,518,840 - 16,587,009 (+)NCBI
RefSeq Acc Id: XM_038521144   ⟹   XP_038377072
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13616,518,419 - 16,586,840 (+)NCBI
RefSeq Acc Id: XM_038584844   ⟹   XP_038440772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03616,621,778 - 16,690,546 (+)NCBI
RefSeq Acc Id: XM_038584845   ⟹   XP_038440773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03616,621,373 - 16,690,377 (+)NCBI
RefSeq Acc Id: XM_038649259   ⟹   XP_038505187
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03616,518,385 - 16,587,468 (+)NCBI
RefSeq Acc Id: XM_038649260   ⟹   XP_038505188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03616,518,212 - 16,587,299 (+)NCBI
RefSeq Acc Id: XM_844987   ⟹   XP_850080
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13616,310,695 - 16,378,029 (+)NCBI
Dog10K_Boxer_Tasha3616,319,988 - 16,386,968 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005640366   ⟸   XM_005640309
- Peptide Label: isoform X2
- UniProtKB: A0A8I3Q513 (UniProtKB/TrEMBL),   A0A8P0PGE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_850080   ⟸   XM_844987
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1A3 (UniProtKB/TrEMBL),   A0A8C0JSI3 (UniProtKB/TrEMBL),   A0A8I3S6P1 (UniProtKB/TrEMBL),   A0A8I3Q513 (UniProtKB/TrEMBL),   A0A8P0PGE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000018999   ⟸   ENSCAFT00000020472
RefSeq Acc Id: ENSCAFP00000064392   ⟸   ENSCAFT00000061844
RefSeq Acc Id: XP_038377072   ⟸   XM_038521144
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038377071   ⟸   XM_038521143
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505188   ⟸   XM_038649260
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038505187   ⟸   XM_038649259
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038302993   ⟸   XM_038447065
- Peptide Label: isoform X2
- UniProtKB: A0A8I3Q513 (UniProtKB/TrEMBL),   A0A8P0PGE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038302992   ⟸   XM_038447064
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1A3 (UniProtKB/TrEMBL),   A0A8C0JSI3 (UniProtKB/TrEMBL),   A0A8I3S6P1 (UniProtKB/TrEMBL),   A0A8I3Q513 (UniProtKB/TrEMBL),   A0A8P0PGE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440773   ⟸   XM_038584845
- Peptide Label: isoform X2
- UniProtKB: A0A8I3Q513 (UniProtKB/TrEMBL),   A0A8P0PGE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440772   ⟸   XM_038584844
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1A3 (UniProtKB/TrEMBL),   A0A8I3Q513 (UniProtKB/TrEMBL),   A0A8I3S6P1 (UniProtKB/TrEMBL),   A0A8C0JSI3 (UniProtKB/TrEMBL),   A0A8P0PGE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845039227   ⟸   ENSCAFT00845050029
RefSeq Acc Id: ENSCAFP00845039276   ⟸   ENSCAFT00845050091
Protein Domains
Histone acetyl transferase HAT1 N-terminal   Histone acetyltransferase type B catalytic subunit


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012890 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030012722 UniProtKB/TrEMBL
  ENSCAFG00040008880 UniProtKB/TrEMBL
  ENSCAFG00845028352 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020472.5 UniProtKB/TrEMBL
  ENSCAFT00000061844.2 UniProtKB/TrEMBL
  ENSCAFT00000100499.1 UniProtKB/TrEMBL
  ENSCAFT00030023633.1 UniProtKB/TrEMBL
  ENSCAFT00040016584.1 UniProtKB/TrEMBL
  ENSCAFT00845050029 ENTREZGENE
  ENSCAFT00845050029.1 UniProtKB/TrEMBL
  ENSCAFT00845050091.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.390 UniProtKB/TrEMBL
  3.40.630.30 UniProtKB/TrEMBL
  3.90.360.10 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  HAT1_C UniProtKB/TrEMBL
  Hat1_N UniProtKB/TrEMBL
  Hat1_N_sf UniProtKB/TrEMBL
  Hist_AcTrfase_B-typ_cat-su UniProtKB/TrEMBL
  Hist_AcTrfase_HAT1_C UniProtKB/TrEMBL
NCBI Gene HAT1 ENTREZGENE
PANTHER HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT UniProtKB/TrEMBL
  PTHR12046 UniProtKB/TrEMBL
Pfam HAT1_C UniProtKB/TrEMBL
  Hat1_N UniProtKB/TrEMBL
PIRSF HAT-B_cat UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/TrEMBL
UniProt A0A8C0JSI3 ENTREZGENE
  A0A8C0S1A3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q513 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S6P1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PCZ5_CANLF UniProtKB/TrEMBL
  A0A8P0PGE0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:50624 ENTREZGENE