DCHS1 (dachsous cadherin-related 1) - Rat Genome Database

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Gene: DCHS1 (dachsous cadherin-related 1) Canis lupus familiaris
Analyze
Symbol: DCHS1 (Ensembl: MRPL17)
Name: dachsous cadherin-related 1
RGD ID: 12050981
Description: ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN anatomical structure morphogenesis (ortholog); branching involved in ureteric bud morphogenesis (ortholog); cell migration (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN apical part of cell (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dachsous 1; protocadherin-16
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,927,713 - 29,955,742 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,928,176 - 29,948,713 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,629,571 - 29,664,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,753,896 - 30,788,761 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2130,753,914 - 30,816,785 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12130,074,653 - 30,109,506 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,240,306 - 30,275,200 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,435,640 - 30,470,548 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
DCHS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,927,713 - 29,955,742 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,928,176 - 29,948,713 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,629,571 - 29,664,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,753,896 - 30,788,761 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2130,753,914 - 30,816,785 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12130,074,653 - 30,109,506 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,240,306 - 30,275,200 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,435,640 - 30,470,548 (-)NCBIUU_Cfam_GSD_1.0
DCHS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,621,330 - 6,655,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,621,330 - 6,655,809 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,642,561 - 6,677,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,599,134 - 6,633,656 (-)NCBINCBI36Build 36hg18NCBI36
Build 34116,599,133 - 6,633,431NCBI
Celera116,761,623 - 6,801,774 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,301,489 - 6,321,899 (-)NCBIHuRef
CHM1_1116,641,459 - 6,675,831 (-)NCBICHM1_1
T2T-CHM13v2.0116,679,797 - 6,714,267 (-)NCBIT2T-CHM13v2.0
Dchs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,402,196 - 105,437,562 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,402,197 - 105,436,861 (-)EnsemblGRCm39 Ensembl
GRCm387105,752,989 - 105,788,355 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,752,990 - 105,787,654 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,901,503 - 112,936,064 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,626,810 - 105,661,745 (-)NCBIMGSCv36mm8
Celera7106,024,342 - 106,044,662 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.98NCBI
Dchs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,516,758 - 169,550,789 (-)NCBIGRCr8
mRatBN7.21160,104,931 - 160,138,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1160,104,931 - 160,124,808 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1168,127,491 - 168,147,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01175,313,488 - 175,333,368 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,215,246 - 168,235,124 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01170,594,981 - 170,629,062 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,594,822 - 170,628,915 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01177,600,833 - 177,634,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,497,340 - 163,517,217 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11163,593,288 - 163,612,580 (-)NCBI
Celera1158,036,763 - 158,056,640 (-)NCBICelera
Cytogenetic Map1q32NCBI
Dchs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541422,332,059 - 22,351,576 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541422,331,590 - 22,365,761 (-)NCBIChiLan1.0ChiLan1.0
DCHS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v299,058,520 - 9,092,876 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1119,022,344 - 9,056,708 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,753,383 - 6,787,896 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,436,082 - 6,456,464 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,436,536 - 6,456,352 (-)Ensemblpanpan1.1panPan2
Dchs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494755,970,003 - 55,998,070 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936842677,416 - 697,003 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936842677,416 - 697,013 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCHS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl93,113,451 - 3,134,821 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.193,099,525 - 3,134,825 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,765,872 - 3,792,053 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DCHS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,170,494 - 58,204,156 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl158,184,591 - 58,205,962 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038155,996,267 - 156,029,917 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dchs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248178,111,718 - 8,134,342 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248178,111,714 - 8,147,699 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DCHS1
283 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 21 5 6 5 6 4 12 8 10 6
Below cutoff 1 1 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000010588   ⟹   ENSCAFP00000009817
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2129,928,176 - 29,948,713 (-)Ensembl
RefSeq Acc Id: XM_022407776   ⟹   XP_022263484
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12129,927,713 - 29,955,742 (-)NCBI
Dog10K_Boxer_Tasha2129,629,571 - 29,657,796 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038430368   ⟹   XP_038286296
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02130,753,896 - 30,788,761 (-)NCBI
RefSeq Acc Id: XM_038430369   ⟹   XP_038286297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02130,753,896 - 30,782,117 (-)NCBI
RefSeq Acc Id: XM_038456329   ⟹   XP_038312257
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2129,629,571 - 29,664,439 (-)NCBI
RefSeq Acc Id: XM_038505697   ⟹   XP_038361625
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12130,074,653 - 30,109,506 (-)NCBI
RefSeq Acc Id: XM_038568905   ⟹   XP_038424833
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02130,435,640 - 30,470,548 (-)NCBI
RefSeq Acc Id: XM_038568906   ⟹   XP_038424834
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02130,435,640 - 30,463,897 (-)NCBI
RefSeq Acc Id: XM_038633071   ⟹   XP_038488999
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02130,240,306 - 30,275,200 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_022263484   ⟸   XM_022407776
- UniProtKB: A0A8C0Q387 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000009817   ⟸   ENSCAFT00000010588
RefSeq Acc Id: XP_038361625   ⟸   XM_038505697
RefSeq Acc Id: XP_038488999   ⟸   XM_038633071
RefSeq Acc Id: XP_038286296   ⟸   XM_038430368
- UniProtKB: A0A8C0Q387 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286297   ⟸   XM_038430369
- UniProtKB: A0A8C0Q387 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038312257   ⟸   XM_038456329
- UniProtKB: A0A8C0Q387 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424833   ⟸   XM_038568905
- UniProtKB: A0A8C0Q387 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424834   ⟸   XM_038568906
- UniProtKB: A0A8C0Q387 (UniProtKB/TrEMBL)
Protein Domains
Cadherin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006532 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040004811 UniProtKB/TrEMBL
  ENSCAFG00845009119 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010588.7 UniProtKB/TrEMBL
  ENSCAFT00040009069.1 UniProtKB/TrEMBL
  ENSCAFT00845016081.1 UniProtKB/TrEMBL
  ENSCAFT00845016164 ENTREZGENE
  ENSCAFT00845016164.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1030.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Ribosomal_L17 UniProtKB/TrEMBL
  Ribosomal_L17_sf UniProtKB/TrEMBL
NCBI Gene DCHS1 ENTREZGENE
PANTHER CADHERIN-23 UniProtKB/TrEMBL
  CADHERIN-87A UniProtKB/TrEMBL
  NEURAL-CADHERIN 2-RELATED UniProtKB/TrEMBL
  PROTOCADHERIN-7 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Ribosomal_L17 UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
  SSF64263 UniProtKB/TrEMBL
UniProt A0A8C0Q387 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N090_CANLF UniProtKB/TrEMBL
  A0A8I3NMG8_CANLF UniProtKB/TrEMBL
  A0A8P0N952_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:52251 ENTREZGENE