HEATR5A (HEAT repeat containing 5A) - Rat Genome Database

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Gene: HEATR5A (HEAT repeat containing 5A) Pan paniscus
Analyze
Symbol: HEATR5A
Name: HEAT repeat containing 5A
RGD ID: 12044614
Description: INVOLVED IN endocytosis (inferred); protein localization (inferred); retrograde transport, endosome to Golgi (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN cytosol (inferred); endocytic vesicle (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HEAT repeat-containing protein 5A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21532,622,546 - 32,751,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01412,070,011 - 12,230,065 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11430,267,861 - 30,395,893 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1430,267,861 - 30,395,893 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
HEATR5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21532,622,546 - 32,751,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01412,070,011 - 12,230,065 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11430,267,861 - 30,395,893 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1430,267,861 - 30,395,893 (-)Ensemblpanpan1.1panPan2
HEATR5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381431,291,788 - 31,420,550 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1431,291,788 - 31,420,550 (-)EnsemblGRCh38hg38GRCh38
GRCh371431,760,994 - 31,889,756 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,832,103 - 30,927,932 (-)NCBINCBI36Build 36hg18NCBI36
Build 341430,831,558 - 30,922,706NCBI
Celera1411,626,496 - 11,723,479 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,878,270 - 12,007,294 (-)NCBIHuRef
CHM1_11431,760,051 - 31,888,641 (-)NCBICHM1_1
T2T-CHM13v2.01425,489,675 - 25,618,192 (-)NCBIT2T-CHM13v2.0
Heatr5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,922,654 - 52,018,154 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,922,654 - 52,018,104 (-)EnsemblGRCm39 Ensembl
GRCm381251,875,871 - 51,971,371 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,875,871 - 51,971,321 (-)EnsemblGRCm38mm10GRCm38
MGSCv371252,976,860 - 53,072,308 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361252,797,493 - 52,892,941 (-)NCBIMGSCv36mm8
Celera1253,180,906 - 53,275,990 (-)NCBICelera
Cytogenetic Map12C1NCBI
Heatr5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8675,057,226 - 75,155,207 (-)NCBIGRCr8
mRatBN7.2669,321,869 - 69,419,861 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl669,321,869 - 69,419,773 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0672,648,654 - 72,750,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,648,662 - 72,750,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0682,211,311 - 82,299,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4672,024,109 - 72,112,681 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera668,197,744 - 68,295,557 (-)NCBICelera
Cytogenetic Map6q23NCBI
Heatr5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,208,050 - 29,312,752 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540929,208,050 - 29,312,752 (+)NCBIChiLan1.0ChiLan1.0
HEATR5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1810,561,723 - 10,673,506 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl810,562,425 - 10,658,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha810,488,485 - 10,522,654 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0810,663,584 - 10,775,409 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,663,658 - 10,775,356 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1810,346,098 - 10,457,867 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0810,423,220 - 10,534,811 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,707,243 - 10,819,049 (-)NCBIUU_Cfam_GSD_1.0
Heatr5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864042,396,649 - 42,518,372 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,903,892 - 6,008,582 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,902,543 - 6,024,106 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEATR5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,211,624 - 68,259,794 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,143,597 - 68,259,087 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,024,717 - 73,140,661 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Heatr5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624820907,396 - 1,021,455 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624820891,562 - 1,022,586 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000045463   ⟹   ENSPPAP00000022652
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1430,267,861 - 30,395,893 (-)Ensembl
RefSeq Acc Id: XM_003821204   ⟹   XP_003821252
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,751,726 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBI
Mhudiblu_PPA_v01412,070,011 - 12,198,811 (-)NCBI
PanPan1.11430,267,861 - 30,395,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008974690   ⟹   XP_008972938
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,741,287 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,957,791 (-)NCBI
Mhudiblu_PPA_v01412,070,011 - 12,230,065 (-)NCBI
PanPan1.11430,267,861 - 30,385,927 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008974692   ⟹   XP_008972940
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,751,727 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBI
Mhudiblu_PPA_v01412,070,011 - 12,198,811 (-)NCBI
PanPan1.11430,267,861 - 30,395,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024925479   ⟹   XP_024781247
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,751,726 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBI
Mhudiblu_PPA_v01412,070,011 - 12,198,811 (-)NCBI
PanPan1.11430,267,861 - 30,395,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034937393   ⟹   XP_034793284
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,751,727 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBI
Mhudiblu_PPA_v01412,070,011 - 12,198,811 (-)NCBI
RefSeq Acc Id: XM_055097454   ⟹   XP_054953429
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,741,287 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,957,791 (-)NCBI
RefSeq Acc Id: XM_055097455   ⟹   XP_054953430
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,751,727 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBI
RefSeq Acc Id: XM_055097456   ⟹   XP_054953431
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,741,287 (-)NCBI
NHGRI_mPanPan11431,839,050 - 31,957,791 (-)NCBI
RefSeq Acc Id: XM_063596178   ⟹   XP_063452248
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,622,546 - 32,741,287 (-)NCBI
RefSeq Acc Id: XM_063596179   ⟹   XP_063452249
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,624,657 - 32,751,728 (-)NCBI
RefSeq Acc Id: XR_010109793
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,624,826 - 32,751,728 (-)NCBI
RefSeq Acc Id: XR_010109794
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21532,624,826 - 32,751,728 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008972940   ⟸   XM_008974692
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B3B7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003821252   ⟸   XM_003821204
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B3B7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008972938   ⟸   XM_008974690
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B3B7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024781247   ⟸   XM_024925479
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B3B7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034793284   ⟸   XM_034937393
- Peptide Label: isoform X5
- UniProtKB: A0A2R9B3B7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000022652   ⟸   ENSPPAT00000045463
RefSeq Acc Id: XP_054953430   ⟸   XM_055097455
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054953431   ⟸   XM_055097456
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054953429   ⟸   XM_055097454
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063452248   ⟸   XM_063596178
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063452249   ⟸   XM_063596179
- Peptide Label: isoform X6


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034508 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045463.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Laa1/Sip1/HEATR5 UniProtKB/TrEMBL
  Laa1/Sip1/HEATR5-like_HEAT UniProtKB/TrEMBL
KEGG Report pps:100993729 UniProtKB/TrEMBL
NCBI Gene HEATR5A ENTREZGENE
PANTHER HEAT REPEAT-CONTAINING PROTEIN 5A UniProtKB/TrEMBL
  PTHR21663 UniProtKB/TrEMBL
Pfam Laa1_Sip1_HTR5 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9B3B7 ENTREZGENE, UniProtKB/TrEMBL