LOC100986729 (aldo-keto reductase family 1 member C1) - Rat Genome Database

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Gene: LOC100986729 (aldo-keto reductase family 1 member C1) Pan paniscus
Analyze
Symbol: LOC100986729 (Ensembl: AKR1C1)
Name: aldo-keto reductase family 1 member C1
RGD ID: 12040656
Description: ENCODES a protein that exhibits aldose reductase (NADPH) activity (inferred); androsterone dehydrogenase activity (inferred); bile acid binding (inferred); INVOLVED IN daunorubicin metabolic process (inferred); doxorubicin metabolic process (inferred); progesterone metabolic process (inferred); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AKR1C1; aldo-keto reductase family 1 member C1 homolog; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1, 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); LOC117974484; uncharacterized LOC117974484
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2817,443,133 - 17,532,013 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11017,417,332 - 17,539,341 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0105,003,610 - 5,020,648 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1104,990,062 - 4,999,894 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl104,990,110 - 5,003,538 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000041854   ⟹   ENSPPAP00000019103
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl104,990,110 - 5,003,538 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041855   ⟹   ENSPPAP00000019104
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl104,990,469 - 4,996,373 (+)Ensembl
RefSeq Acc Id: XM_034929869   ⟹   XP_034785760
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2817,510,605 - 17,532,013 (+)NCBI
NHGRI_mPanPan11017,517,026 - 17,539,341 (+)NCBI
Mhudiblu_PPA_v0105,005,967 - 5,020,648 (+)NCBI
RefSeq Acc Id: XM_063607230   ⟹   XP_063463300
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2817,516,725 - 17,532,013 (+)NCBI
RefSeq Acc Id: XM_063607231   ⟹   XP_063463301
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2817,443,133 - 17,532,013 (+)NCBI
RefSeq Acc Id: XM_063607232   ⟹   XP_063463302
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2817,497,941 - 17,532,013 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034785760 (Get FASTA)   NCBI Sequence Viewer  
  XP_063463300 (Get FASTA)   NCBI Sequence Viewer  
  XP_063463301 (Get FASTA)   NCBI Sequence Viewer  
  XP_063463302 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000019104.1
Reference Protein Sequences
RefSeq Acc Id: XP_034785760   ⟸   XM_034929869
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000019103   ⟸   ENSPPAT00000041854
RefSeq Acc Id: ENSPPAP00000019104   ⟸   ENSPPAT00000041855
RefSeq Acc Id: XP_063463301   ⟸   XM_063607231
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063463302   ⟸   XM_063607232
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063463300   ⟸   XM_063607230
- Peptide Label: isoform X1
Protein Domains
NADP-dependent oxidoreductase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032724 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041855.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.100 UniProtKB/TrEMBL
InterPro AKR UniProtKB/TrEMBL
  Aldo/ket_reductase_CS UniProtKB/TrEMBL
  NADP_OxRdtase_dom UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/TrEMBL
NCBI Gene LOC100986729 ENTREZGENE
PANTHER ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1-RELATED UniProtKB/TrEMBL
  ALDO/KETO REDUCTASE UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/TrEMBL
PRINTS ALDKETRDTASE UniProtKB/TrEMBL
PROSITE ALDOKETO_REDUCTASE_1 UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF51430 UniProtKB/TrEMBL
UniProt A0A2R9AVW5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-25 LOC100986729  aldo-keto reductase family 1 member C1  LOC100986729  aldo-keto reductase family 1 member C1 homolog  Symbol and/or name change 5135510 APPROVED
2023-04-20 LOC100986729  aldo-keto reductase family 1 member C1 homolog  LOC117974484  uncharacterized LOC117974484  Data merged from RGD:32729928 737654 PROVISIONAL
2020-07-01 LOC100986729  aldo-keto reductase family 1 member C1 homolog  LOC100986729  aldo-keto reductase family 1 member C1  Symbol and/or name change 5135510 APPROVED