SZT2 (SZT2 subunit of KICSTOR complex) - Rat Genome Database

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Gene: SZT2 (SZT2 subunit of KICSTOR complex) Pan paniscus
Analyze
Symbol: SZT2
Name: SZT2 subunit of KICSTOR complex
RGD ID: 12037433
Description: INVOLVED IN central nervous system development (ortholog); pigmentation (ortholog); post-embryonic development (ortholog); ASSOCIATED WITH benign epilepsy with centrotemporal spikes (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); cryptorchidism (ortholog); FOUND IN GATOR1 complex (ortholog); GATOR2 complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: KICSTOR complex protein SZT2; seizure threshold 2 homolog; seizure threshold 2 homolog (mouse); SZT2 subunit KICSTOR complex; SZT2, KICSTOR complex subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21183,358,884 - 183,420,155 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,500,263 - 182,561,533 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,691,292 - 42,754,046 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,068,936 - 44,130,135 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,068,998 - 44,129,456 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SZT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21183,358,884 - 183,420,155 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,500,263 - 182,561,533 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,691,292 - 42,754,046 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,068,936 - 44,130,135 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,068,998 - 44,129,456 (+)Ensemblpanpan1.1panPan2
SZT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,389,899 - 43,454,247 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,389,882 - 43,454,247 (+)EnsemblGRCh38hg38GRCh38
GRCh37143,855,570 - 43,919,918 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36143,661,384 - 43,690,891 (+)NCBINCBI36Build 36hg18NCBI36
Celera142,170,952 - 42,200,501 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef141,974,692 - 42,039,063 (+)NCBIHuRef
CHM1_1143,972,005 - 44,036,286 (+)NCBICHM1_1
T2T-CHM13v2.0143,260,449 - 43,324,500 (+)NCBIT2T-CHM13v2.0
Szt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394118,219,937 - 118,266,483 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4118,219,940 - 118,266,470 (-)EnsemblGRCm39 Ensembl
GRCm384118,362,740 - 118,409,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4118,362,743 - 118,409,273 (-)EnsemblGRCm38mm10GRCm38
MGSCv374118,035,350 - 118,081,868 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364117,860,675 - 117,872,979 (-)NCBIMGSCv36mm8
Celera4117,085,125 - 117,131,926 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map454.61NCBI
Szt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85137,182,648 - 137,229,349 (-)NCBIGRCr8
mRatBN7.25131,897,250 - 131,943,953 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,897,275 - 131,943,904 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05137,192,120 - 137,238,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5137,190,875 - 137,238,354 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05140,979,672 - 141,025,913 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.05142,699,676 - 142,711,040 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,843,690 - 138,890,241 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15138,849,231 - 138,871,344 (-)NCBI
Celera5130,442,737 - 130,489,407 (-)NCBICelera
Cytogenetic Map5q36NCBI
Szt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555372,968,839 - 3,017,863 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555372,968,839 - 3,017,863 (+)NCBIChiLan1.0ChiLan1.0
SZT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,729,068 - 16,780,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,728,758 - 16,780,325 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1516,856,152 - 16,907,502 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01516,895,853 - 16,947,211 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,882,688 - 16,947,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,688,557 - 16,739,725 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,757,341 - 16,808,681 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,830,906 - 16,882,264 (-)NCBIUU_Cfam_GSD_1.0
Szt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505858,963,361 - 59,014,228 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647424,788,195 - 24,837,395 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647424,788,175 - 24,837,471 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SZT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,811,598 - 167,861,583 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16167,811,589 - 167,861,321 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26155,228,017 - 155,236,352 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SZT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12089,360,859 - 89,422,554 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603327,499,023 - 27,560,769 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Szt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248922,703,936 - 2,756,565 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248922,703,898 - 2,754,130 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047620   ⟹   ENSPPAP00000024795
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl144,068,998 - 44,129,456 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000047624   ⟹   ENSPPAP00000024799
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl144,068,998 - 44,129,456 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000047625   ⟹   ENSPPAP00000024800
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl144,068,998 - 44,084,986 (+)Ensembl
RefSeq Acc Id: XM_003812838   ⟹   XP_003812886
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21183,358,884 - 183,420,155 (-)NCBI
NHGRI_mPanPan11182,500,263 - 182,561,533 (-)NCBI
Mhudiblu_PPA_v0142,691,292 - 42,754,046 (+)NCBI
PanPan1.1144,068,936 - 44,130,135 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063608225   ⟹   XP_063464295
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21183,358,884 - 183,420,124 (-)NCBI
RefSeq Acc Id: XM_063608226   ⟹   XP_063464296
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21183,358,884 - 183,387,881 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003812886 (Get FASTA)   NCBI Sequence Viewer  
  XP_063464295 (Get FASTA)   NCBI Sequence Viewer  
  XP_063464296 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024795.1
  ENSPPAP00000024799.1
  ENSPPAP00000024800.1
Reference Protein Sequences
RefSeq Acc Id: XP_003812886   ⟸   XM_003812838
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000024800   ⟸   ENSPPAT00000047625
RefSeq Acc Id: ENSPPAP00000024799   ⟸   ENSPPAT00000047624
RefSeq Acc Id: ENSPPAP00000024795   ⟸   ENSPPAT00000047620
RefSeq Acc Id: XP_063464295   ⟸   XM_063608225
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063464296   ⟸   XM_063608226
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047620.1 UniProtKB/TrEMBL
  ENSPPAT00000047624.1 UniProtKB/TrEMBL
  ENSPPAT00000047625.1 UniProtKB/TrEMBL
InterPro SZT2 UniProtKB/TrEMBL
NCBI Gene SZT2 ENTREZGENE
PANTHER KICSTOR COMPLEX PROTEIN SZT2 UniProtKB/TrEMBL
  PTHR14918 UniProtKB/TrEMBL
UniProt A0A2R9B945_PANPA UniProtKB/TrEMBL
  A0A2R9B950_PANPA UniProtKB/TrEMBL
  A0A2R9BCB3_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-26 SZT2  SZT2 subunit of KICSTOR complex  SZT2  SZT2 subunit KICSTOR complex  Symbol and/or name change 5135510 APPROVED
2019-01-29 SZT2  SZT2 subunit KICSTOR complex    SZT2, KICSTOR complex subunit  Symbol and/or name change 5135510 APPROVED
2017-05-23 SZT2  SZT2, KICSTOR complex subunit    seizure threshold 2 homolog (mouse)  Symbol and/or name change 5135510 APPROVED