PPP6R1 (protein phosphatase 6 regulatory subunit 1) - Rat Genome Database

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Gene: PPP6R1 (protein phosphatase 6 regulatory subunit 1) Pan paniscus
Analyze
Symbol: PPP6R1
Name: protein phosphatase 6 regulatory subunit 1
RGD ID: 12031234
Description: ENCODES a protein that exhibits protein phosphatase binding (inferred); protein phosphatase regulator activity (inferred); small GTPase binding (inferred); ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); nemaline myopathy 5A (ortholog); FOUND IN cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein phosphatase 6 regulatory subunit 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,365,415 - 61,394,988 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,094,519 - 63,124,090 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,270,215 - 52,299,824 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11960,962,375 - 60,991,643 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1960,962,375 - 60,991,643 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPP6R1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,365,415 - 61,394,988 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,094,519 - 63,124,090 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,270,215 - 52,299,824 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11960,962,375 - 60,991,643 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1960,962,375 - 60,991,643 (-)Ensemblpanpan1.1panPan2
PPP6R1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,228,218 - 55,259,017 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,229,779 - 55,259,017 (-)EnsemblGRCh38hg38GRCh38
GRCh371955,741,147 - 55,770,385 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,432,959 - 60,461,850 (-)NCBINCBI36Build 36hg18NCBI36
Build 341960,432,959 - 60,461,739NCBI
Celera1952,782,683 - 52,799,998 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,064,519 - 52,093,406 (-)NCBIHuRef
CHM1_11955,734,672 - 55,763,556 (-)NCBICHM1_1
T2T-CHM13v2.01958,322,178 - 58,352,962 (-)NCBIT2T-CHM13v2.0
Ppp6r1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,634,494 - 4,661,949 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,634,494 - 4,662,018 (-)EnsemblGRCm39 Ensembl
GRCm3874,631,495 - 4,658,950 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,631,495 - 4,659,019 (-)EnsemblGRCm38mm10GRCm38
MGSCv3774,583,097 - 4,610,552 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,234,582 - 4,262,037 (-)NCBIMGSCv36mm8
Celera74,362,647 - 4,388,723 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.68NCBI
Ppp6r1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,218,629 - 78,246,360 (+)NCBIGRCr8
mRatBN7.2169,190,856 - 69,217,598 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,189,822 - 69,216,272 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,535,880 - 74,562,607 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,100,179 - 83,126,914 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,253,031 - 76,279,791 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,756,819 - 72,784,492 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,756,809 - 72,784,482 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,750,748 - 75,778,885 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,907,512 - 67,934,242 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,995,230 - 68,011,918 (+)NCBI
Celera167,907,382 - 67,933,897 (-)NCBICelera
Cytogenetic Map1q12NCBI
Ppp6r1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567972,633 - 985,075 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955567966,483 - 985,692 (+)NCBIChiLan1.0ChiLan1.0
PPP6R1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,406,257 - 102,427,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,406,524 - 102,426,755 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,463,059 - 102,483,892 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01103,059,568 - 103,080,405 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1103,059,499 - 103,080,394 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,696,551 - 102,717,359 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,408,268 - 102,429,071 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,172,117 - 103,192,953 (+)NCBIUU_Cfam_GSD_1.0
Ppp6r1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,038,071 - 2,058,830 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886500,395 - 511,799 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936886500,395 - 511,802 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP6R1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,427,572 - 59,450,109 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,427,901 - 59,447,692 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,395,850 - 54,418,945 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPP6R1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,827,766 - 47,847,945 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045426,017 - 456,133 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp6r1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248322,023,166 - 2,034,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248322,013,539 - 2,034,854 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000049222   ⟹   ENSPPAP00000026389
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1960,962,375 - 60,991,643 (-)Ensembl
RefSeq Acc Id: XM_003807107   ⟹   XP_003807155
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22061,365,415 - 61,394,988 (-)NCBI
NHGRI_mPanPan11963,094,519 - 63,124,090 (-)NCBI
Mhudiblu_PPA_v01952,270,215 - 52,299,824 (-)NCBI
PanPan1.11960,962,375 - 60,991,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034946789   ⟹   XP_034802680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22061,365,415 - 61,383,013 (-)NCBI
NHGRI_mPanPan11963,094,519 - 63,112,111 (-)NCBI
Mhudiblu_PPA_v01952,270,216 - 52,287,849 (-)NCBI
RefSeq Acc Id: XM_055104206   ⟹   XP_054960181
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22061,365,415 - 61,393,033 (-)NCBI
NHGRI_mPanPan11963,094,519 - 63,122,131 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003807155 (Get FASTA)   NCBI Sequence Viewer  
  XP_034802680 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960181 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000026389.1
Reference Protein Sequences
RefSeq Acc Id: XP_003807155   ⟸   XM_003807107
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034802680   ⟸   XM_034946789
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000026389   ⟸   ENSPPAT00000049222
RefSeq Acc Id: XP_054960181   ⟸   XM_055104206
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049222.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  SAPS UniProtKB/TrEMBL
NCBI Gene PPP6R1 ENTREZGENE
PANTHER PTHR12634 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 1 UniProtKB/TrEMBL
Pfam SAPS UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9B9W9_PANPA UniProtKB/TrEMBL