GSS (glutathione synthetase) - Rat Genome Database

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Gene: GSS (glutathione synthetase) Pan paniscus
Analyze
Symbol: GSS
Name: glutathione synthetase
RGD ID: 11988282
Description: ENCODES a protein that exhibits ATP binding (ortholog); glutathione binding (ortholog); glutathione synthase activity (ortholog); INVOLVED IN glutathione biosynthetic process (ortholog); response to amino acid (ortholog); response to cadmium ion (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; glutathione metabolic pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); Alzheimer's disease (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,661,205 - 40,688,813 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,654,308 - 40,682,219 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02031,256,734 - 31,284,356 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,381,745 - 32,409,327 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,381,745 - 32,409,297 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GSS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,661,205 - 40,688,813 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,654,308 - 40,682,219 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02031,256,734 - 31,284,356 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,381,745 - 32,409,327 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,381,745 - 32,409,297 (-)Ensemblpanpan1.1panPan2
GSS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382034,928,432 - 34,956,027 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2034,928,432 - 34,956,027 (-)EnsemblGRCh38hg38GRCh38
GRCh372033,516,235 - 33,543,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,979,897 - 33,007,262 (-)NCBINCBI36Build 36hg18NCBI36
Build 342032,979,897 - 33,007,262NCBI
Celera2030,265,329 - 30,292,695 (-)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2030,294,556 - 30,321,979 (-)NCBIHuRef
CHM1_12033,417,456 - 33,444,826 (-)NCBICHM1_1
T2T-CHM13v2.02036,649,086 - 36,676,682 (-)NCBIT2T-CHM13v2.0
Gss
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,405,101 - 155,434,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2155,405,101 - 155,434,730 (-)EnsemblGRCm39 Ensembl
GRCm382155,563,181 - 155,592,810 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,563,181 - 155,592,810 (-)EnsemblGRCm38mm10GRCm38
MGSCv372155,388,919 - 155,418,442 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362155,254,624 - 155,284,147 (-)NCBIMGSCv36mm8
Celera2161,495,432 - 161,524,969 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.26NCBI
Gss
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,508,005 - 164,538,343 (-)NCBIGRCr8
mRatBN7.23144,047,849 - 144,078,197 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3144,047,850 - 144,078,198 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3147,914,375 - 147,944,469 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,531,652 - 156,561,750 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,271,186 - 154,301,288 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03151,076,254 - 151,106,557 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,076,254 - 151,106,557 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,443,738 - 157,474,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43146,057,517 - 146,087,820 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13145,963,138 - 145,993,442 (-)NCBI
Celera3142,772,407 - 142,802,700 (-)NCBICelera
Cytogenetic Map3q42NCBI
Gss
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,427,581 - 26,463,781 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,427,581 - 26,483,380 (+)NCBIChiLan1.0ChiLan1.0
GSS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12423,973,807 - 24,000,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2423,901,045 - 23,997,286 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,619,971 - 23,646,466 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,665,657 - 24,692,375 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,665,043 - 24,692,288 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12423,952,937 - 23,979,420 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02424,048,251 - 24,074,736 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,487,171 - 24,513,688 (-)NCBIUU_Cfam_GSD_1.0
Gss
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640172,955,595 - 172,983,992 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365615,765,610 - 5,793,567 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365615,765,637 - 5,793,951 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,312,720 - 38,342,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,316,199 - 38,342,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21743,511,098 - 43,539,281 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1239,230,629 - 39,258,511 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl239,230,487 - 39,254,648 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605087,554,278 - 87,582,240 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gss
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248424,446,721 - 4,478,450 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248424,445,015 - 4,470,124 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000034576   ⟹   ENSPPAP00000011914
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2032,381,745 - 32,409,297 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000034579   ⟹   ENSPPAP00000011917
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2032,382,140 - 32,405,171 (-)Ensembl
RefSeq Acc Id: XM_003831835   ⟹   XP_003831883
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,661,205 - 40,688,666 (-)NCBI
NHGRI_mPanPan12040,654,308 - 40,681,769 (-)NCBI
Mhudiblu_PPA_v02031,256,734 - 31,284,177 (-)NCBI
PanPan1.12032,381,745 - 32,409,123 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008957219   ⟹   XP_008955467
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,661,205 - 40,688,813 (-)NCBI
NHGRI_mPanPan12040,654,308 - 40,682,219 (-)NCBI
Mhudiblu_PPA_v02031,256,734 - 31,284,356 (-)NCBI
PanPan1.12032,381,745 - 32,409,327 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014343028   ⟹   XP_014198514
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22140,661,205 - 40,688,550 (-)NCBI
NHGRI_mPanPan12040,654,308 - 40,681,653 (-)NCBI
Mhudiblu_PPA_v02031,256,734 - 31,283,945 (-)NCBI
PanPan1.12032,381,745 - 32,408,928 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003831883 (Get FASTA)   NCBI Sequence Viewer  
  XP_008955467 (Get FASTA)   NCBI Sequence Viewer  
  XP_014198514 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000011914
  ENSPPAP00000011914.1
  ENSPPAP00000011917.1
RefSeq Acc Id: XP_008955467   ⟸   XM_008957219
- UniProtKB: A0A2R9A4W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003831883   ⟸   XM_003831835
- UniProtKB: A0A2R9A4W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014198514   ⟸   XM_014343028
- UniProtKB: A0A2R9A4W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000011917   ⟸   ENSPPAT00000034579
RefSeq Acc Id: ENSPPAP00000011914   ⟸   ENSPPAT00000034576

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029155 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034576.1 UniProtKB/TrEMBL
  ENSPPAT00000034579.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.50 UniProtKB/TrEMBL
  3.30.1490.80 UniProtKB/TrEMBL
  3.40.50.1760 UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/TrEMBL
InterPro Glutathione_synthase UniProtKB/TrEMBL
  Glutathione_synthase_a-hlx UniProtKB/TrEMBL
  Glutathione_synthase_C_euk UniProtKB/TrEMBL
  Glutathione_synthase_N_euk UniProtKB/TrEMBL
  GSH-S_sub-bd_sf UniProtKB/TrEMBL
  GSH_synth_subst-bd UniProtKB/TrEMBL
  PreATP-grasp_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100980165 UniProtKB/TrEMBL
NCBI Gene GSS ENTREZGENE
PANTHER GLUTATHIONE SYNTHETASE UniProtKB/TrEMBL
  PTHR11130 UniProtKB/TrEMBL
Pfam GSH_synth_ATP UniProtKB/TrEMBL
  GSH_synthase UniProtKB/TrEMBL
PIRSF GSHase UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
  SSF52440 UniProtKB/TrEMBL
UniProt A0A2R9A3L8_PANPA UniProtKB/TrEMBL
  A0A2R9A4W7 ENTREZGENE, UniProtKB/TrEMBL