ARHGEF16 (Rho guanine nucleotide exchange factor 16) - Rat Genome Database

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Gene: ARHGEF16 (Rho guanine nucleotide exchange factor 16) Pan paniscus
Analyze
Symbol: ARHGEF16
Name: Rho guanine nucleotide exchange factor 16
RGD ID: 11985048
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); PDZ domain binding (inferred); receptor tyrosine kinase binding (inferred); INVOLVED IN cell chemotaxis (inferred); positive regulation of protein localization to plasma membrane (inferred); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); Ehlers-Danlos syndrome spondylodysplastic type 2 (ortholog); immunodeficiency 16 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21224,832,003 - 224,859,350 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,477,657 - 223,505,186 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012,121,058 - 2,148,391 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113,258,189 - 3,276,337 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13,258,664 - 3,275,809 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGEF16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21224,832,003 - 224,859,350 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,477,657 - 223,505,186 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012,121,058 - 2,148,391 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113,258,189 - 3,276,337 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13,258,664 - 3,275,809 (+)Ensemblpanpan1.1panPan2
ARHGEF16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813,454,665 - 3,481,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13,454,665 - 3,481,113 (+)EnsemblGRCh38hg38GRCh38
GRCh3713,371,229 - 3,397,677 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613,369,982 - 3,387,537 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413,403,278 - 3,420,832NCBI
Celera12,624,447 - 2,650,733 (+)NCBICelera
Cytogenetic Map1p36.32NCBI
HuRef12,663,841 - 2,692,412 (+)NCBIHuRef
CHM1_113,357,218 - 3,384,706 (+)NCBICHM1_1
T2T-CHM13v2.012,959,327 - 2,988,135 (+)NCBIT2T-CHM13v2.0
Arhgef16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394154,362,926 - 154,384,535 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4154,362,943 - 154,386,133 (-)EnsemblGRCm39 Ensembl
GRCm384154,278,469 - 154,300,107 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4154,278,486 - 154,301,676 (-)EnsemblGRCm38mm10GRCm38
MGSCv374153,652,579 - 153,674,004 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364153,122,270 - 153,144,133 (-)NCBIMGSCv36mm8
Celera4156,565,792 - 156,575,315 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.96NCBI
Arhgef16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,126,573 - 170,148,624 (-)NCBIGRCr8
mRatBN7.25164,843,656 - 164,866,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,844,161 - 164,866,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5167,548,321 - 167,570,389 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,369,735 - 169,391,803 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,332,254 - 169,354,323 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,626,450 - 171,649,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,624,796 - 171,648,563 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,097,644 - 175,120,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5163,054,279 - 163,076,331 (-)NCBICelera
Cytogenetic Map5q36NCBI
Arhgef16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554868,109,291 - 8,123,404 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554868,109,291 - 8,128,184 (-)NCBIChiLan1.0ChiLan1.0
ARHGEF16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1558,031,246 - 58,051,936 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl558,030,459 - 58,051,936 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha558,042,558 - 58,063,422 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0558,232,977 - 58,253,909 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl558,233,018 - 58,253,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1558,247,674 - 58,268,510 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0558,116,370 - 58,137,240 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0558,506,497 - 58,527,429 (+)NCBIUU_Cfam_GSD_1.0
Arhgef16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505829,067,527 - 29,096,097 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936737369,852 - 383,719 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936737369,872 - 383,671 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl665,027,442 - 65,048,542 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1665,026,490 - 65,048,545 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2659,773,558 - 59,794,924 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120128,204,517 - 128,229,866 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605432,483,595 - 32,510,575 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248186,949,484 - 6,966,237 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248186,949,484 - 6,966,195 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000024778   ⟹   ENSPPAP00000005451
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl13,258,664 - 3,275,809 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000024779   ⟹   ENSPPAP00000005452
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl13,258,664 - 3,275,809 (+)Ensembl
RefSeq Acc Id: XM_034953721   ⟹   XP_034809612
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21224,832,003 - 224,859,350 (-)NCBI
NHGRI_mPanPan11223,477,657 - 223,505,186 (-)NCBI
Mhudiblu_PPA_v012,121,313 - 2,148,391 (+)NCBI
RefSeq Acc Id: XM_063602267   ⟹   XP_063458337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21224,832,010 - 224,859,350 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034809612 (Get FASTA)   NCBI Sequence Viewer  
  XP_063458337 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005451.1
  ENSPPAP00000005452.1
Reference Protein Sequences
RefSeq Acc Id: XP_034809612   ⟸   XM_034953721
RefSeq Acc Id: ENSPPAP00000005452   ⟸   ENSPPAT00000024779
RefSeq Acc Id: ENSPPAP00000005451   ⟸   ENSPPAT00000024778
RefSeq Acc Id: XP_063458337   ⟸   XM_063602267
Protein Domains
DH   PH   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000022572 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000024778.1 UniProtKB/TrEMBL
  ENSPPAT00000024779.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ARHGEF16/ARHGEF26_SH3 UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  Ephexin-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PH_ephexin UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene ARHGEF16 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE EXCHANGE FACTOR UniProtKB/TrEMBL
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A2R8ZKG8_PANPA UniProtKB/TrEMBL
  A0A2R8ZRI6_PANPA UniProtKB/TrEMBL