ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) - Rat Genome Database

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Gene: ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) Pan paniscus
Analyze
Symbol: ABHD4
Name: abhydrolase domain containing 4, N-acyl phospholipase B
RGD ID: 11983930
Description: ENCODES a protein that exhibits lysophosphatidic acid acyltransferase activity (inferred); lysophospholipase activity (inferred); INVOLVED IN N-acylethanolamine metabolic process (ortholog); N-acylphosphatidylethanolamine metabolic process (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); FOUND IN lipid droplet (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: (Lyso)-N-acylphosphatidylethanolamine lipase; abhydrolase domain containing 4; abhydrolase domain-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,046,482 - 24,060,604 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,262,968 - 23,277,090 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,434,357 - 3,448,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,535,753 - 21,549,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,535,753 - 21,549,856 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ABHD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,046,482 - 24,060,604 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,262,968 - 23,277,090 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,434,357 - 3,448,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,535,753 - 21,549,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,535,753 - 21,549,856 (+)Ensemblpanpan1.1panPan2
ABHD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,598,300 - 22,612,963 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,598,290 - 22,612,963 (+)EnsemblGRCh38hg38GRCh38
GRCh371423,067,209 - 23,081,869 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,136,987 - 22,151,105 (+)NCBINCBI36Build 36hg18NCBI36
Build 341422,136,986 - 22,151,104NCBI
Celera142,930,195 - 2,944,309 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,185,554 - 3,199,668 (+)NCBIHuRef
CHM1_11423,066,140 - 23,080,261 (+)NCBICHM1_1
T2T-CHM13v2.01416,796,030 - 16,810,693 (+)NCBIT2T-CHM13v2.0
Abhd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,491,586 - 54,506,626 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,491,645 - 54,508,094 (+)EnsemblGRCm39 Ensembl
GRCm381454,254,129 - 54,269,169 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,254,188 - 54,270,637 (+)EnsemblGRCm38mm10GRCm38
MGSCv371454,878,972 - 54,888,840 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,217,302 - 53,227,172 (+)NCBIMGSCv36mm8
Celera1452,055,549 - 52,065,503 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.71NCBI
Abhd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,674,090 - 31,686,051 (+)NCBIGRCr8
mRatBN7.21527,697,384 - 27,716,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,704,113 - 27,716,966 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,545,656 - 29,557,577 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,692,485 - 30,704,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01528,942,527 - 28,954,454 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01532,888,233 - 32,906,861 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1532,894,938 - 32,906,850 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,699,362 - 36,717,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,312,516 - 32,325,153 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,328,007 - 32,340,852 (+)NCBI
Celera1527,285,833 - 27,297,758 (+)NCBICelera
Cytogenetic Map15p13NCBI
Abhd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,650,109 - 37,663,459 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,650,220 - 37,662,950 (-)NCBIChiLan1.0ChiLan1.0
ABHD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.182,997,112 - 3,011,524 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl82,997,202 - 3,011,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha82,946,776 - 2,961,187 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,104,518 - 3,118,934 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,104,608 - 3,119,469 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.182,797,208 - 2,811,610 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.082,858,617 - 2,873,025 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,120,646 - 3,135,054 (+)NCBIUU_Cfam_GSD_1.0
Abhd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,717,075 - 34,730,431 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,658,302 - 1,671,853 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,658,287 - 1,671,848 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,396,484 - 76,431,809 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,396,548 - 76,431,836 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,633,143 - 81,656,262 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12922,967,290 - 22,981,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2922,967,374 - 22,979,622 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,442,642 - 23,465,028 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248259,088,957 - 9,102,419 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248259,088,907 - 9,101,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038424   ⟹   ENSPPAP00000015733
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1421,535,753 - 21,549,856 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038428   ⟹   ENSPPAP00000015737
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1421,535,817 - 21,548,446 (+)Ensembl
RefSeq Acc Id: XM_003808131   ⟹   XP_003808179
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21524,046,482 - 24,060,604 (+)NCBI
NHGRI_mPanPan11423,262,968 - 23,277,090 (+)NCBI
Mhudiblu_PPA_v0143,434,357 - 3,448,471 (+)NCBI
PanPan1.11421,535,753 - 21,549,856 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063596166   ⟹   XP_063452236
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21524,046,572 - 24,060,604 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003808179 (Get FASTA)   NCBI Sequence Viewer  
  XP_063452236 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000015733
  ENSPPAP00000015733.1
  ENSPPAP00000015737.1
Reference Protein Sequences
RefSeq Acc Id: XP_003808179   ⟸   XM_003808131
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AL41 (UniProtKB/TrEMBL),   A0A2R9AFJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000015737   ⟸   ENSPPAT00000038428
RefSeq Acc Id: ENSPPAP00000015733   ⟸   ENSPPAT00000038424
RefSeq Acc Id: XP_063452236   ⟸   XM_063596166
- Peptide Label: isoform X2
Protein Domains
AB hydrolase-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030993 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038424.1 UniProtKB/TrEMBL
  ENSPPAT00000038428.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
KEGG Report pps:100993408 UniProtKB/TrEMBL
NCBI Gene ABHD4 ENTREZGENE
PANTHER (LYSO)-N-ACYLPHOSPHATIDYLETHANOLAMINE LIPASE UniProtKB/TrEMBL
  RE40534P-RELATED UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PRINTS ABHYDROLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9AFJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AL41 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-28 ABHD4  abhydrolase domain containing 4, N-acyl phospholipase B  ABHD4  abhydrolase domain containing 4  Symbol and/or name change 5135510 APPROVED