SEMA3E (semaphorin 3E) - Rat Genome Database

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Gene: SEMA3E (semaphorin 3E) Pan paniscus
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Symbol: SEMA3E
Name: semaphorin 3E
RGD ID: 11965167
Description: ENCODES a protein that exhibits chemorepellent activity (inferred); receptor ligand activity (inferred); semaphorin receptor binding (inferred); INVOLVED IN axon guidance (inferred); branching involved in blood vessel morphogenesis (inferred); gonadotrophin-releasing hormone neuronal migration to the hypothalamus (inferred); ASSOCIATED WITH amenorrhea (ortholog); CHARGE syndrome (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: semaphorin-3E
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26101,216,178 - 101,499,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17149,480,816 - 149,764,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0775,329,049 - 75,612,946 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1788,994,889 - 89,274,073 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl788,995,049 - 89,274,241 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEMA3E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26101,216,178 - 101,499,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17149,480,816 - 149,764,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0775,329,049 - 75,612,946 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1788,994,889 - 89,274,073 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl788,995,049 - 89,274,241 (-)Ensemblpanpan1.1panPan2
SEMA3E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38783,363,238 - 83,649,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl783,363,238 - 83,649,139 (-)EnsemblGRCh38hg38GRCh38
GRCh37782,992,554 - 83,278,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36782,831,158 - 83,116,260 (-)NCBINCBI36Build 36hg18NCBI36
Build 34782,637,872 - 82,922,975NCBI
Celera777,694,433 - 77,979,877 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef777,887,145 - 77,887,879 (-)NCBIHuRef
HuRef777,595,681 - 77,739,611 (-)NCBIHuRef
CHM1_1782,923,279 - 83,208,527 (-)NCBICHM1_1
T2T-CHM13v2.0784,614,452 - 84,899,593 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2782,325,430 - 82,610,645 (-)NCBI
Sema3e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39514,075,290 - 14,306,703 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl514,075,290 - 14,306,703 (+)EnsemblGRCm39 Ensembl
GRCm38514,025,276 - 14,256,689 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl514,025,276 - 14,256,689 (+)EnsemblGRCm38mm10GRCm38
MGSCv37514,025,276 - 14,256,689 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36514,031,321 - 14,260,320 (+)NCBIMGSCv36mm8
Celera1224,396,140 - 24,628,407 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map55.66NCBI
Sema3e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8421,252,686 - 21,510,449 (-)NCBIGRCr8
mRatBN7.2420,297,534 - 20,555,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl420,299,718 - 20,555,229 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx425,487,004 - 25,736,649 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0421,330,088 - 21,579,569 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0419,713,113 - 19,962,579 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0417,314,745 - 17,594,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl417,272,511 - 17,594,598 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0417,560,774 - 17,563,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0417,288,508 - 17,411,535 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4416,523,602 - 16,781,878 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1416,525,151 - 16,673,253 (-)NCBI
Celera415,809,991 - 16,063,707 (-)NCBICelera
Cytogenetic Map4q12NCBI
Sema3e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554102,732,996 - 2,831,210 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554102,732,983 - 2,831,220 (+)NCBIChiLan1.0ChiLan1.0
SEMA3E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11822,881,135 - 22,982,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1822,881,133 - 23,116,696 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1822,557,413 - 22,793,028 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01823,332,852 - 23,568,629 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1823,332,879 - 23,569,152 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11822,967,259 - 23,202,826 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01822,502,891 - 22,738,629 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01823,164,304 - 23,400,247 (-)NCBIUU_Cfam_GSD_1.0
Sema3e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511864,648,977 - 64,883,826 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367341,850,673 - 2,084,891 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367341,850,709 - 2,085,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA3E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl996,682,246 - 96,941,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1996,682,178 - 96,941,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29106,872,688 - 107,135,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA3E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12165,255,610 - 65,529,021 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2165,415,373 - 65,533,090 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604238,431,351 - 38,737,423 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema3e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473931,608,501 - 31,716,640 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473931,606,128 - 31,851,624 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000034271   ⟹   ENSPPAP00000011611
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl788,995,049 - 89,274,241 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000034279   ⟹   ENSPPAP00000011619
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl788,995,049 - 89,121,920 (-)Ensembl
RefSeq Acc Id: XM_003822740   ⟹   XP_003822788
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26101,216,178 - 101,499,795 (-)NCBI
NHGRI_mPanPan17149,480,816 - 149,764,439 (-)NCBI
Mhudiblu_PPA_v0775,329,049 - 75,612,936 (-)NCBI
PanPan1.1788,994,889 - 89,274,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034964340   ⟹   XP_034820231
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26101,221,656 - 101,499,805 (-)NCBI
NHGRI_mPanPan17149,486,291 - 149,764,448 (-)NCBI
Mhudiblu_PPA_v0775,334,533 - 75,612,946 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003822788 (Get FASTA)   NCBI Sequence Viewer  
  XP_034820231 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000011611
  ENSPPAP00000011611.1
  ENSPPAP00000011619.1
RefSeq Acc Id: XP_003822788   ⟸   XM_003822740
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A876 (UniProtKB/TrEMBL),   A0A2R9A419 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034820231   ⟸   XM_034964340
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A419 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000011619   ⟸   ENSPPAT00000034279
RefSeq Acc Id: ENSPPAP00000011611   ⟸   ENSPPAT00000034271
Protein Domains
Ig-like   Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029005 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034271.1 UniProtKB/TrEMBL
  ENSPPAT00000034279.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  Semaphorin_3E UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100982463 UniProtKB/TrEMBL
NCBI Gene SEMA3E ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  PTHR11036:SF22 UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  SEMA UniProtKB/TrEMBL
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9A419 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A876 ENTREZGENE, UniProtKB/TrEMBL