APOBEC3B (apolipoprotein B mRNA editing enzyme catalytic subunit 3B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: APOBEC3B (apolipoprotein B mRNA editing enzyme catalytic subunit 3B) Pan paniscus
Analyze
Symbol: APOBEC3B
Name: apolipoprotein B mRNA editing enzyme catalytic subunit 3B
RGD ID: 11955223
Description: ENCODES a protein that exhibits cytidine deaminase activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN clearance of foreign intracellular DNA (ortholog); retrotransposon silencing (ortholog); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Breast Neoplasms (ortholog); disease of cellular proliferation (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; DNA dC->dU-editing enzyme APOBEC-3B
RGD Orthologs
Human
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,833,423 - 48,843,446 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,524,896 - 51,534,810 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,892,548 - 19,902,455 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,711,473 - 37,761,454 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,711,588 - 37,721,265 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (ISO)
nucleus  (IEA)
P-body  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:24153179   PMID:30032202  


Genomics

Comparative Map Data
APOBEC3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,833,423 - 48,843,446 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,524,896 - 51,534,810 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,892,548 - 19,902,455 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,711,473 - 37,761,454 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,711,588 - 37,721,265 (+)Ensemblpanpan1.1panPan2
APOBEC3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,982,347 - 38,992,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,982,347 - 38,992,804 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,378,352 - 39,388,784 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,708,351 - 37,718,729 (+)NCBINCBI36Build 36hg18NCBI36
Build 342237,702,904 - 37,713,283NCBI
Celera2223,180,435 - 23,190,818 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,346,831 - 22,357,255 (+)NCBIHuRef
CHM1_12239,337,368 - 39,347,749 (+)NCBICHM1_1
T2T-CHM13v2.02239,452,733 - 39,463,200 (+)NCBIT2T-CHM13v2.0
APOBEC3B
(Chlorocebus sabaeus - green monkey)		 No map positions available.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000010449   ⟹   ENSPPAP00000002122
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2237,711,588 - 37,721,265 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000010494   ⟹   ENSPPAP00000002130
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2237,711,588 - 37,721,222 (+)Ensembl
RefSeq Acc Id: NM_001301766   ⟹   NP_001288695
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22348,833,423 - 48,843,328 (+)NCBI
NHGRI_mPanPan12251,524,896 - 51,534,810 (+)NCBI
Mhudiblu_PPA_v02219,892,548 - 19,902,455 (+)NCBI
PanPan1.12237,711,588 - 37,721,222 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063603031   ⟹   XP_063459101
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22348,834,655 - 48,843,446 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001288695 (Get FASTA)   NCBI Sequence Viewer  
  XP_063459101 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADO85885 (Get FASTA)   NCBI Sequence Viewer  
  AER45718 (Get FASTA)   NCBI Sequence Viewer  
  AHF72556 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000002122.1
  ENSPPAP00000002130
  ENSPPAP00000002130.1
Reference Protein Sequences
RefSeq Acc Id: NP_001288695   ⟸   NM_001301766
- UniProtKB: W0HFS6 (UniProtKB/TrEMBL),   A0A2R8ZET4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000002122   ⟸   ENSPPAT00000010449
RefSeq Acc Id: ENSPPAP00000002130   ⟸   ENSPPAT00000010494
RefSeq Acc Id: XP_063459101   ⟸   XM_063603031
- Peptide Label: isoform X1
Protein Domains
CMP/dCMP-type deaminase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000009288 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000010449.1 UniProtKB/TrEMBL
  ENSPPAT00000010494 ENTREZGENE
  ENSPPAT00000010494.1 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/TrEMBL
InterPro APOBEC/CMP_deaminase_Zn-bd UniProtKB/TrEMBL
  CMP_dCMP_dom UniProtKB/TrEMBL
  Cytidine_deaminase-like UniProtKB/TrEMBL
KEGG Report pps:100971498 UniProtKB/TrEMBL
NCBI Gene APOBEC3B ENTREZGENE
PANTHER DNA DC-DU-EDITING ENZYME APOBEC-3A-RELATED UniProtKB/TrEMBL
  MRNA EDITING ENZYME UniProtKB/TrEMBL
Pfam NAD2 UniProtKB/TrEMBL
PROSITE CYT_DCMP_DEAMINASES_1 UniProtKB/TrEMBL
  CYT_DCMP_DEAMINASES_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53927 UniProtKB/TrEMBL
UniProt A0A2R8ZAR6_PANPA UniProtKB/TrEMBL
  A0A2R8ZET4 ENTREZGENE, UniProtKB/TrEMBL
  W0HFS6 ENTREZGENE, UniProtKB/TrEMBL