LOC100971854 (5-hydroxytryptamine receptor 3E) - Rat Genome Database

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Gene: LOC100971854 (5-hydroxytryptamine receptor 3E) Pan paniscus
Analyze
Symbol: LOC100971854 (Ensembl: HTR3E)
Name: 5-hydroxytryptamine receptor 3E
RGD ID: 11941562
Description: ENCODES a protein that exhibits acetylcholine-gated monoatomic cation-selective channel activity (inferred); extracellular ligand-gated monoatomic ion channel activity (inferred); serotonin-gated monoatomic cation channel activity (inferred); INVOLVED IN chemical synaptic transmission (inferred); excitatory postsynaptic potential (inferred); inorganic cation transmembrane transport (inferred); ASSOCIATED WITH 3-Methylcrotonyl-CoA carboxylase 1 deficiency (ortholog); congenital disorder of glycosylation Id (ortholog); Currarino syndrome (ortholog); FOUND IN serotonin-activated cation-selective channel complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HTR3E
RGD Orthologs
Human
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,969,082 - 181,978,668 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,973,798 - 181,983,384 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03181,133,013 - 181,142,639 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,298,987 - 189,625,481 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3189,299,453 - 189,625,179 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100971854
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,969,082 - 181,978,668 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,973,798 - 181,983,384 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03181,133,013 - 181,142,639 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,298,987 - 189,625,481 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3189,299,453 - 189,625,179 (+)Ensemblpanpan1.1panPan2
HTR3E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,097,064 - 184,106,995 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3184,097,064 - 184,106,995 (+)EnsemblGRCh38hg38GRCh38
GRCh373183,814,852 - 183,824,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,300,661 - 185,307,477 (+)NCBINCBI36Build 36hg18NCBI36
Build 343185,300,668 - 185,307,484NCBI
Celera3182,260,576 - 182,267,055 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,222,305 - 181,232,240 (+)NCBIHuRef
CHM1_13183,779,221 - 183,789,185 (+)NCBICHM1_1
T2T-CHM13v2.03186,906,628 - 186,916,555 (+)NCBIT2T-CHM13v2.0
LOC100856260
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13417,011,403 - 17,019,214 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,011,555 - 17,018,941 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3421,098,890 - 21,106,537 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03416,919,302 - 16,926,942 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3416,919,302 - 16,926,681 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13416,957,069 - 16,964,708 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03416,952,821 - 16,960,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03417,183,003 - 17,190,874 (+)NCBIUU_Cfam_GSD_1.0
HTR3E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,314,837 - 5,324,086 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606314,096,374 - 14,105,331 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000033694   ⟹   ENSPPAP00000011039
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3189,299,453 - 189,625,179 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000033701   ⟹   ENSPPAP00000011046
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3189,302,188 - 189,625,179 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000033702   ⟹   ENSPPAP00000011047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3189,302,188 - 189,625,179 (+)Ensembl
RefSeq Acc Id: XM_057301962   ⟹   XP_057157945
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,969,082 - 181,978,668 (+)NCBI
NHGRI_mPanPan13181,973,798 - 181,983,384 (+)NCBI
RefSeq Acc Id: XM_057301963   ⟹   XP_057157946
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,969,082 - 181,978,668 (+)NCBI
NHGRI_mPanPan13181,973,798 - 181,983,384 (+)NCBI
RefSeq Acc Id: XM_057301964   ⟹   XP_057157947
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22181,970,491 - 181,978,668 (+)NCBI
NHGRI_mPanPan13181,975,207 - 181,983,384 (+)NCBI
Protein Sequences
Protein RefSeqs XP_057157945 (Get FASTA)   NCBI Sequence Viewer  
  XP_057157946 (Get FASTA)   NCBI Sequence Viewer  
  XP_057157947 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000011039.1
  ENSPPAP00000011046.1
  ENSPPAP00000011047.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000011039   ⟸   ENSPPAT00000033694
RefSeq Acc Id: ENSPPAP00000011047   ⟸   ENSPPAT00000033702
RefSeq Acc Id: ENSPPAP00000011046   ⟸   ENSPPAT00000033701
RefSeq Acc Id: XP_057157945   ⟸   XM_057301962
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A2G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057157946   ⟸   XM_057301963
- Peptide Label: isoform X2
RefSeq Acc Id: XP_057157947   ⟸   XM_057301964
- Peptide Label: isoform X3
- UniProtKB: A0A2R9A6R8 (UniProtKB/TrEMBL)
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028726 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033694.1 UniProtKB/TrEMBL
  ENSPPAT00000033701.1 UniProtKB/TrEMBL
  ENSPPAT00000033702.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
NCBI Gene LOC100971854 ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR 3E UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A2R9A1B4_PANPA UniProtKB/TrEMBL
  A0A2R9A2G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A6R8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-25 LOC100971854  5-hydroxytryptamine receptor 3E  HTR3E  5-hydroxytryptamine receptor 3E  Symbol and/or name change 5135510 APPROVED
2018-05-08 HTR3E  5-hydroxytryptamine receptor 3E  LOC100971854    Symbol and/or name change 5135510 APPROVED