LOC100981962 (aflatoxin B1 aldehyde reductase member 2) - Rat Genome Database

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Gene: LOC100981962 (aflatoxin B1 aldehyde reductase member 2) Pan paniscus
Analyze
Symbol: LOC100981962 (Ensembl: AKR7A2)
Name: aflatoxin B1 aldehyde reductase member 2 (Ensembl:aldo-keto reductase family 7 member A2)
RGD ID: 11940168
Description: ENCODES a protein that exhibits aldose reductase (NADPH) activity (ortholog); INVOLVED IN daunorubicin metabolic process (inferred); doxorubicin metabolic process (inferred); ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); Alzheimer's disease (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aflatoxin B1 aldehyde reductase member 4; AKR7A2; aldo-keto reductase family 7 member A2; aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,802,957 - 207,822,054 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,919,935 - 206,938,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,262,631 - 18,270,783 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,309,211 - 19,317,836 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,309,471 - 19,317,227 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
LOC100981962
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,802,957 - 207,822,054 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,919,935 - 206,938,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,262,631 - 18,270,783 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,309,211 - 19,317,836 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,309,471 - 19,317,227 (-)Ensemblpanpan1.1panPan2
AKR7A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,302,708 - 19,312,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,303,965 - 19,312,144 (-)EnsemblGRCh38hg38GRCh38
GRCh37119,629,202 - 19,638,640 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,503,046 - 19,511,227 (-)NCBINCBI36Build 36hg18NCBI36
Build 34119,375,768 - 19,383,946NCBI
Celera117,957,442 - 17,965,624 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef117,875,577 - 17,884,829 (-)NCBIHuRef
CHM1_1119,738,505 - 19,747,943 (-)NCBICHM1_1
T2T-CHM13v2.0119,126,242 - 19,135,681 (-)NCBIT2T-CHM13v2.0
Akr7a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394139,038,005 - 139,046,097 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4139,038,055 - 139,045,737 (+)EnsemblGRCm39 Ensembl
GRCm384139,310,720 - 139,318,786 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,310,744 - 139,318,426 (+)EnsemblGRCm38mm10GRCm38
MGSCv374138,866,659 - 138,874,701 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,582,820 - 138,590,501 (+)NCBIMGSCv36mm8
Celera4141,097,258 - 141,105,993 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.64NCBI
Akr7a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,835,589 - 156,844,127 (+)NCBIGRCr8
mRatBN7.25151,552,375 - 151,560,914 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,552,343 - 151,560,909 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5154,250,866 - 154,259,404 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05156,025,214 - 156,033,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05156,006,202 - 156,014,739 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,759,448 - 157,768,473 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,759,416 - 157,768,471 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,499,603 - 161,508,628 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45158,097,679 - 158,106,217 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15158,107,717 - 158,116,254 (+)NCBI
Celera5149,932,592 - 149,941,127 (+)NCBICelera
Cytogenetic Map5q36NCBI
Akr7a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554526,844 - 13,868 (-)NCBIChiLan1.0ChiLan1.0
AKR7A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1279,334,179 - 79,343,880 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl279,334,205 - 79,343,007 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,849,105 - 75,858,155 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,956,898 - 79,965,951 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,956,898 - 79,968,886 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,717,803 - 76,726,853 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,727,438 - 77,736,710 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,798,535 - 78,808,663 (+)NCBIUU_Cfam_GSD_1.0
LOC101974041
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505839,740,406 - 39,748,246 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364745,565,715 - 5,573,048 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKR7A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl677,754,174 - 77,761,667 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1677,754,172 - 77,761,609 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2671,816,268 - 71,823,705 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225480
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120113,234,257 - 113,242,445 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660332,916,852 - 2,925,038 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034956910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000036403   ⟹   ENSPPAP00000013729
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl119,309,471 - 19,317,227 (-)Ensembl
RefSeq Acc Id: XM_034956910   ⟹   XP_034812801
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21207,802,957 - 207,822,054 (+)NCBI
NHGRI_mPanPan11206,919,935 - 206,938,840 (+)NCBI
Mhudiblu_PPA_v0118,262,631 - 18,270,783 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034812801 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013729.1
Reference Protein Sequences
RefSeq Acc Id: XP_034812801   ⟸   XM_034956910
RefSeq Acc Id: ENSPPAP00000013729   ⟸   ENSPPAT00000036403
Protein Domains
NADP-dependent oxidoreductase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030032 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036403.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.100 UniProtKB/TrEMBL
InterPro NADP_OxRdtase_dom UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/TrEMBL
NCBI Gene LOC100981962 ENTREZGENE
PANTHER NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN UniProtKB/TrEMBL
  NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/TrEMBL
Superfamily-SCOP SSF51430 UniProtKB/TrEMBL
UniProt A0A2R9A8Y5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-03-13 LOC100981962  aflatoxin B1 aldehyde reductase member 2  AKR7A2  aldo-keto reductase family 7 member A2  Symbol and/or name change 5135510 APPROVED
2023-04-25 AKR7A2  aldo-keto reductase family 7 member A2  LOC100981962  aflatoxin B1 aldehyde reductase member 2  Symbol and/or name change 5135510 APPROVED
2020-07-01 LOC100981962  aflatoxin B1 aldehyde reductase member 2  LOC100981962  aflatoxin B1 aldehyde reductase member 4  Symbol and/or name change 5135510 APPROVED