ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2) - Rat Genome Database

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Gene: ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2) Pan paniscus
Analyze
Symbol: ARAP2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
RGD ID: 11934721
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol-3,4,5-trisphosphate binding (inferred); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2336,243,314 - 36,462,448 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1436,432,386 - 36,651,468 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0430,382,528 - 30,561,731 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1436,244,283 - 36,422,965 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl436,244,283 - 36,422,965 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2336,243,314 - 36,462,448 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1436,432,386 - 36,651,468 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0430,382,528 - 30,561,731 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1436,244,283 - 36,422,965 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl436,244,283 - 36,422,965 (-)Ensemblpanpan1.1panPan2
ARAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38436,005,404 - 36,244,784 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl435,948,221 - 36,244,514 (-)EnsemblGRCh38hg38GRCh38
GRCh37436,007,026 - 36,246,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36435,744,017 - 35,922,374 (-)NCBINCBI36Build 36hg18NCBI36
Build 34435,890,187 - 35,983,929NCBI
Celera436,507,143 - 36,685,553 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef435,394,038 - 35,572,297 (-)NCBIHuRef
CHM1_1436,066,734 - 36,245,096 (-)NCBICHM1_1
T2T-CHM13v2.0435,974,325 - 36,213,757 (-)NCBIT2T-CHM13v2.0
Arap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39562,759,788 - 62,923,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl562,759,788 - 62,923,502 (-)EnsemblGRCm39 Ensembl
GRCm38562,602,445 - 62,766,192 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl562,602,445 - 62,766,159 (-)EnsemblGRCm38mm10GRCm38
MGSCv37562,993,684 - 63,157,416 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36562,890,682 - 63,054,331 (-)NCBIMGSCv36mm8
Celera559,899,718 - 60,063,218 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map532.04NCBI
Arap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81450,921,323 - 51,120,972 (+)NCBIGRCr8
mRatBN7.21446,717,657 - 46,917,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1446,718,760 - 46,917,154 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1451,125,503 - 51,322,104 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01452,427,974 - 52,624,570 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01448,824,406 - 49,021,017 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01448,726,033 - 48,922,809 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1448,726,045 - 48,922,983 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01448,892,214 - 49,090,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41450,594,829 - 50,789,829 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11450,611,833 - 50,790,398 (+)NCBI
Celera1446,023,257 - 46,220,741 (+)NCBICelera
Cytogenetic Map14q11NCBI
Arap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544310,537,758 - 10,717,301 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544310,537,763 - 10,719,329 (+)NCBIChiLan1.0ChiLan1.0
ARAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1375,641,034 - 75,832,145 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl375,643,013 - 75,815,274 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha378,128,989 - 78,318,159 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0376,422,480 - 76,613,649 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl376,423,621 - 76,614,886 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1375,688,311 - 75,879,140 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0375,844,199 - 76,035,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0376,219,926 - 76,410,644 (+)NCBIUU_Cfam_GSD_1.0
Arap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528541,730,685 - 41,930,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364824,386,934 - 4,553,332 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364824,385,788 - 4,567,646 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl827,771,423 - 27,960,542 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1827,771,413 - 27,960,564 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2829,137,042 - 29,327,243 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12714,036,751 - 14,215,997 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2714,052,478 - 14,214,050 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604760,484,586 - 60,724,580 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248404,635,818 - 4,793,179 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248404,635,446 - 4,809,618 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057021   ⟹   ENSPPAP00000034140
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl436,244,283 - 36,422,965 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057031   ⟹   ENSPPAP00000034150
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl436,244,283 - 36,422,965 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057044   ⟹   ENSPPAP00000034163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl436,259,171 - 36,422,965 (-)Ensembl
RefSeq Acc Id: XM_003832149   ⟹   XP_003832197
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,422,245 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,611,276 (-)NCBI
Mhudiblu_PPA_v0430,382,528 - 30,561,418 (-)NCBI
PanPan1.1436,244,283 - 36,422,965 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034958423   ⟹   XP_034814314
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,421,673 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,610,711 (-)NCBI
Mhudiblu_PPA_v0430,382,530 - 30,560,853 (-)NCBI
RefSeq Acc Id: XM_034958424   ⟹   XP_034814315
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,421,833 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,610,870 (-)NCBI
Mhudiblu_PPA_v0430,382,530 - 30,561,014 (-)NCBI
RefSeq Acc Id: XM_034958425   ⟹   XP_034814316
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,422,558 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,611,587 (-)NCBI
Mhudiblu_PPA_v0430,382,530 - 30,561,731 (-)NCBI
RefSeq Acc Id: XM_034958426   ⟹   XP_034814317
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,421,673 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,610,711 (-)NCBI
Mhudiblu_PPA_v0430,382,530 - 30,560,853 (-)NCBI
RefSeq Acc Id: XM_034958430   ⟹   XP_034814321
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,386,673 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,575,698 (-)NCBI
Mhudiblu_PPA_v0430,384,412 - 30,525,841 (-)NCBI
RefSeq Acc Id: XM_055111263   ⟹   XP_054967238
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,462,448 (-)NCBI
NHGRI_mPanPan1436,432,386 - 36,651,468 (-)NCBI
RefSeq Acc Id: XM_063603753   ⟹   XP_063459823
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,421,673 (-)NCBI
RefSeq Acc Id: XM_063603754   ⟹   XP_063459824
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2336,243,314 - 36,421,674 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003832197   ⟸   XM_003832149
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034814316   ⟸   XM_034958425
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034814315   ⟸   XM_034958424
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034814317   ⟸   XM_034958426
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034814314   ⟸   XM_034958423
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034814321   ⟸   XM_034958430
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000034150   ⟸   ENSPPAT00000057031
RefSeq Acc Id: ENSPPAP00000034163   ⟸   ENSPPAT00000057044
RefSeq Acc Id: ENSPPAP00000034140   ⟸   ENSPPAT00000057021
RefSeq Acc Id: XP_054967238   ⟸   XM_055111263
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063459824   ⟸   XM_063603754
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063459823   ⟸   XM_063603753
- Peptide Label: isoform X2
Protein Domains
Arf-GAP   PH   Ras-associating   Rho-GAP   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039913 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057021.1 UniProtKB/TrEMBL
  ENSPPAT00000057031.1 UniProtKB/TrEMBL
  ENSPPAT00000057044.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.10.220.150 UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  RA_dom UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_ARAP UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
KEGG Report pps:100991376 UniProtKB/TrEMBL
NCBI Gene ARAP2 ENTREZGENE
PANTHER ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C UniProtKB/TrEMBL
Pfam ArfGap UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PS50200 UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART ArfGap UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A2R9BWV3_PANPA UniProtKB/TrEMBL
  A0A2R9C069_PANPA UniProtKB/TrEMBL
  A0A2R9C079_PANPA UniProtKB/TrEMBL