SPINK14 (serine peptidase inhibitor Kazal type 14 (putative)) - Rat Genome Database

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Gene: SPINK14 (serine peptidase inhibitor Kazal type 14 (putative)) Pan paniscus
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Symbol: SPINK14
Name: serine peptidase inhibitor Kazal type 14 (putative)
RGD ID: 11934677
Description: ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine peptidase inhibitor, Kazal type 14 (putative); serine protease inhibitor Kazal-type 14
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24143,402,557 - 143,408,579 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15141,542,107 - 141,548,129 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05143,598,502 - 143,604,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15149,606,819 - 149,612,784 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5149,606,819 - 149,612,784 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
SPINK14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24143,402,557 - 143,408,579 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15141,542,107 - 141,548,129 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05143,598,502 - 143,604,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15149,606,819 - 149,612,784 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5149,606,819 - 149,612,784 (+)Ensemblpanpan1.1panPan2
SPINK14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385148,168,546 - 148,175,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5148,168,546 - 148,175,619 (+)EnsemblGRCh38hg38GRCh38
GRCh375147,548,109 - 147,555,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365147,529,489 - 147,535,154 (+)NCBINCBI36Build 36hg18NCBI36
Celera5143,630,039 - 143,634,356 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5142,696,417 - 142,702,136 (+)NCBIHuRef
CHM1_15146,981,715 - 146,987,380 (+)NCBICHM1_1
T2T-CHM13v2.05148,704,264 - 148,709,980 (+)NCBIT2T-CHM13v2.0
Spink14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391844,160,936 - 44,165,275 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1844,160,936 - 44,165,484 (+)EnsemblGRCm39 Ensembl
GRCm381844,027,869 - 44,032,208 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1844,027,869 - 44,032,417 (+)EnsemblGRCm38mm10GRCm38
MGSCv371844,187,523 - 44,191,862 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361844,153,792 - 44,157,748 (+)NCBIMGSCv36mm8
Celera1845,404,003 - 45,408,310 (+)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1823.74NCBI
Spink14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81836,589,158 - 36,593,309 (+)NCBIGRCr8
mRatBN7.21836,339,223 - 36,341,261 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1836,339,223 - 36,342,144 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1836,443,247 - 36,445,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01837,161,597 - 37,163,635 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01836,538,498 - 36,540,536 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01229,349,133 - 229,351,168 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,196,537 - 35,199,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl236,011,045 - 36,013,966 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1229,349,133 - 229,351,171 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01236,506,634 - 236,508,669 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41837,638,618 - 37,641,539 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11837,673,883 - 37,676,805 (+)NCBI
Cytogenetic Map18q11NCBI
SPINK14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,388,792 - 42,393,375 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,388,311 - 42,393,197 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,431,445 - 39,439,229 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0242,845,240 - 42,853,022 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl242,849,693 - 42,853,029 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1239,915,223 - 39,923,002 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0240,725,232 - 40,733,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,548,458 - 41,556,244 (+)NCBIUU_Cfam_GSD_1.0
Spink14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213145,061,304 - 145,064,879 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365046,635,277 - 6,638,296 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365046,635,277 - 6,638,852 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPINK14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2149,415,857 - 149,424,227 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12149,414,615 - 149,423,473 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22156,181,121 - 156,189,865 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPINK14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603427,059,376 - 27,066,698 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spink14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247747,596,610 - 7,600,661 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003829061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000063967   ⟹   ENSPPAP00000041046
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5149,606,819 - 149,612,784 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000063971   ⟹   ENSPPAP00000041050
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5149,606,906 - 149,612,550 (+)Ensembl
RefSeq Acc Id: XM_003829061   ⟹   XP_003829109
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24143,402,557 - 143,408,579 (+)NCBI
NHGRI_mPanPan15141,542,107 - 141,548,129 (+)NCBI
Mhudiblu_PPA_v05143,598,502 - 143,604,524 (+)NCBI
PanPan1.15149,606,819 - 149,612,784 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003829109 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041046
  ENSPPAP00000041046.1
  ENSPPAP00000041050.1
RefSeq Acc Id: XP_003829109   ⟸   XM_003829061
- UniProtKB: A0A2R9CGE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000041046   ⟸   ENSPPAT00000063967
RefSeq Acc Id: ENSPPAP00000041050   ⟸   ENSPPAT00000063971
Protein Domains
Kazal-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063967.1 UniProtKB/TrEMBL
  ENSPPAT00000063971.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/TrEMBL
InterPro Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100986517 UniProtKB/TrEMBL
NCBI Gene SPINK14 ENTREZGENE
PANTHER SERINE PROTEASE INHIBITOR KAZAL-TYPE 14 UniProtKB/TrEMBL
  SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 UniProtKB/TrEMBL
Pfam Kazal_1 UniProtKB/TrEMBL
PROSITE KAZAL_1 UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
SMART KAZAL UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
UniProt A0A2R9CGE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CGG8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-08 SPINK14  serine peptidase inhibitor Kazal type 14 (putative)  SPINK14  serine peptidase inhibitor, Kazal type 14 (putative)  Symbol and/or name change 5135510 APPROVED