XPOT (exportin for tRNA) - Rat Genome Database

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Gene: XPOT (exportin for tRNA) Pan paniscus
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Symbol: XPOT
Name: exportin for tRNA
RGD ID: 11930415
Description: ENCODES a protein that exhibits small GTPase binding (inferred); tRNA binding (inferred); INVOLVED IN intracellular protein transport (inferred); macromolecule localization (inferred); nucleocytoplasmic transport (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nuclear pore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: exportin, tRNA (nuclear export receptor for tRNAs); exportin-T
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21029,917,982 - 29,962,413 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11229,914,753 - 29,959,184 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01224,469,893 - 24,516,694 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11224,969,881 - 25,016,517 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,969,881 - 25,016,517 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nuclear matrix  (IEA)
nuclear pore  (IEA,ISO)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
XPOT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21029,917,982 - 29,962,413 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11229,914,753 - 29,959,184 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01224,469,893 - 24,516,694 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11224,969,881 - 25,016,517 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,969,881 - 25,016,517 (-)Ensemblpanpan1.1panPan2
XPOT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381264,404,392 - 64,451,125 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1264,404,392 - 64,451,125 (+)EnsemblGRCh38hg38GRCh38
GRCh371264,798,172 - 64,844,905 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361263,084,500 - 63,128,731 (+)NCBINCBI36Build 36hg18NCBI36
Build 341263,084,499 - 63,128,728NCBI
Celera1264,462,903 - 64,506,901 (+)NCBICelera
Cytogenetic Map12q14.2NCBI
HuRef1261,850,500 - 61,894,809 (+)NCBIHuRef
CHM1_11264,765,247 - 64,809,559 (+)NCBICHM1_1
T2T-CHM13v2.01264,382,995 - 64,429,752 (+)NCBIT2T-CHM13v2.0
Xpot
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910121,423,285 - 121,462,411 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10121,423,285 - 121,462,237 (-)EnsemblGRCm39 Ensembl
GRCm3810121,587,380 - 121,626,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,587,380 - 121,626,332 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710121,024,436 - 121,063,372 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610120,990,440 - 121,029,376 (-)NCBIMGSCv36mm8
Celera10123,970,630 - 124,005,131 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1069.86NCBI
Xpot
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8758,997,025 - 59,037,506 (-)NCBIGRCr8
mRatBN7.2757,111,536 - 57,152,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl757,111,536 - 57,152,099 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx759,023,288 - 59,063,697 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0761,226,165 - 61,266,574 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0761,003,873 - 61,044,282 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0763,688,646 - 63,728,988 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl763,690,053 - 63,728,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0763,912,373 - 63,951,227 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,898,206 - 60,937,868 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1760,919,844 - 60,958,675 (-)NCBI
Celera753,854,337 - 53,893,237 (-)NCBICelera
Cytogenetic Map7q22NCBI
Xpot
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545811,162,782 - 11,208,849 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545811,162,612 - 11,206,515 (+)NCBIChiLan1.0ChiLan1.0
XPOT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1107,121,275 - 7,163,692 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl107,121,684 - 7,213,139 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha107,057,551 - 7,099,328 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0107,231,797 - 7,273,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl107,231,781 - 7,273,577 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1107,097,730 - 7,139,500 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0107,349,460 - 7,392,166 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0107,480,924 - 7,522,701 (+)NCBIUU_Cfam_GSD_1.0
Xpot
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494551,349,390 - 51,388,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365452,721,379 - 2,762,793 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365452,721,437 - 2,762,785 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPOT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl528,828,566 - 28,875,325 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1528,678,971 - 28,875,336 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2532,040,486 - 32,075,831 (+)NCBISscrofa10.2Sscrofa10.2susScr3
XPOT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11160,087,492 - 60,132,383 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1160,092,482 - 60,131,948 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037185,672,658 - 185,717,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xpot
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248023,919,994 - 3,953,843 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248023,915,852 - 3,953,791 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000039228   ⟹   ENSPPAP00000016531
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1224,969,881 - 25,016,517 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000039236   ⟹   ENSPPAP00000016539
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1224,972,707 - 25,002,159 (-)Ensembl
RefSeq Acc Id: XM_003824805   ⟹   XP_003824853
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21029,917,982 - 29,962,413 (-)NCBI
NHGRI_mPanPan11229,914,753 - 29,959,184 (-)NCBI
Mhudiblu_PPA_v01224,469,893 - 24,516,694 (-)NCBI
PanPan1.11224,969,881 - 25,016,517 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055096508   ⟹   XP_054952483
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21029,917,982 - 29,962,413 (-)NCBI
NHGRI_mPanPan11229,914,753 - 29,959,184 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003824853 (Get FASTA)   NCBI Sequence Viewer  
  XP_054952483 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000016531
  ENSPPAP00000016531.1
  ENSPPAP00000016539.1
RefSeq Acc Id: XP_003824853   ⟸   XM_003824805
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AGR5 (UniProtKB/TrEMBL),   A0A2R9ANK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000016539   ⟸   ENSPPAT00000039236
RefSeq Acc Id: ENSPPAP00000016531   ⟸   ENSPPAT00000039228
RefSeq Acc Id: XP_054952483   ⟸   XM_055096508
- Peptide Label: isoform X2

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031361 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039228.1 UniProtKB/TrEMBL
  ENSPPAT00000039236.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Exportin-1/Importin-b-like UniProtKB/TrEMBL
  Exportin-T_C UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  XPOT UniProtKB/TrEMBL
KEGG Report pps:100990556 UniProtKB/TrEMBL
NCBI Gene XPOT ENTREZGENE
PANTHER EXPORTIN-T UniProtKB/TrEMBL
  PTHR15952 UniProtKB/TrEMBL
Pfam Exportin-T UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
  Xpo1 UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9AGR5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ANK3 ENTREZGENE, UniProtKB/TrEMBL