LOC100977441 (cytochrome b5 type B)

Gene: LOC100977441 (cytochrome b5 type B) Pan paniscus

Analyze

Symbol:

LOC100977441 (Ensembl: CYB5B)

Name:

cytochrome b5 type B

RGD ID:

11922232

Description:

ENCODES a protein that exhibits enzyme activator activity (ortholog); nitrite reductase (NO-forming) activity (ortholog); INVOLVED IN nitric oxide biosynthetic process (inferred); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial outer membrane (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	78,971,502 - 79,027,929 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	84,883,151 - 84,923,041 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	49,801,900 - 49,843,698 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	69,187,541 - 69,226,744 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	69,187,541 - 69,226,744 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nitric oxide biosynthetic process (IEA)

Cellular Component

intracellular membrane-bounded organelle (IEA)

membrane (IEA)

mitochondrial outer membrane (IEA,ISO)

nitric-oxide synthase complex (IEA)

Molecular Function

enzyme activator activity (ISO)

heme binding (IEA)

metal ion binding (IEA)

nitrite reductase (NO-forming) activity (IEA,ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC100977441
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	78,971,502 - 79,027,929 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	84,883,151 - 84,923,041 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	49,801,900 - 49,843,698 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	69,187,541 - 69,226,744 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	69,187,541 - 69,226,744 (+)	Ensembl	panpan1.1		panPan2

CYB5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	69,424,619 - 69,466,264 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	69,398,402 - 69,466,264 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	69,458,522 - 69,500,167 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	68,015,999 - 68,057,668 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	68,016,063 - 68,055,208	NCBI
Celera	16	53,973,073 - 54,014,760 (+)	NCBI		Celera
Cytogenetic Map	16	q22.1	NCBI
HuRef	16	55,336,597 - 55,378,285 (+)	NCBI		HuRef
CHM1_1	16	70,866,498 - 70,908,170 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	75,226,795 - 75,268,458 (+)	NCBI		T2T-CHM13v2.0

Cyb5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	107,877,293 - 107,914,102 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	107,877,272 - 107,914,103 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	107,150,661 - 107,187,470 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	107,150,640 - 107,187,471 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	109,674,561 - 109,711,370 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	110,039,790 - 110,076,599 (+)	NCBI		MGSCv36	mm8
Celera	8	111,377,448 - 111,414,325 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.71	NCBI

Cyb5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	51,972,611 - 52,006,477 (+)	NCBI		GRCr8
mRatBN7.2	19	35,062,871 - 35,096,741 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	35,062,813 - 35,098,249 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	41,878,337 - 41,912,205 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	42,531,689 - 42,565,561 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	44,836,503 - 44,870,428 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	39,357,814 - 39,391,680 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	39,357,791 - 39,393,189 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	50,221,836 - 50,255,701 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	37,016,959 - 37,050,722 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	37,021,839 - 37,055,599 (+)	NCBI
Celera	19	34,486,613 - 34,520,473 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

LOC102026979
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955484	7,237,906 - 7,271,123 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955484	7,239,364 - 7,270,639 (-)	NCBI	ChiLan1.0	ChiLan1.0

CYB5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	80,204,211 - 80,224,288 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	80,192,689 - 80,231,299 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	80,634,998 - 80,674,838 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	5	80,463,026 - 80,501,679 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	80,151,322 - 80,190,353 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	80,785,370 - 80,824,317 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101972623
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	40,011,922 - 40,046,742 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	19,542,115 - 19,577,678 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	19,542,378 - 19,577,192 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYB5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	17,519,289 - 17,558,181 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	17,522,587 - 17,558,030 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	16,469,821 - 16,505,266 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103233210
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	57,939,055 - 57,978,240 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	57,937,176 - 57,978,449 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	20,669,858 - 20,709,376 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101712938
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624746	16,905,967 - 16,942,861 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003814547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063597703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063597704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000039840 ⟹ ENSPPAP00000017140

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	16	69,187,541 - 69,226,744 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000039854 ⟹ ENSPPAP00000017154

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	16	69,187,737 - 69,225,317 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000039858 ⟹ ENSPPAP00000017158

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	16	69,187,737 - 69,225,317 (+)	Ensembl

RefSeq Acc Id:

XM_003814547 ⟹ XP_003814595

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	78,971,502 - 79,011,392 (+)	NCBI
NHGRI_mPanPan1	16	84,883,151 - 84,923,041 (+)	NCBI
Mhudiblu_PPA_v0	16	49,801,900 - 49,843,698 (+)	NCBI
PanPan1.1	16	69,187,541 - 69,226,744 (+)	NCBI

Sequence:

show sequence

GAACTGAGCCACTCCCTTCATTGGTGAAAAGAAAACGAACCAGGAACTATTCGGAAGTGTGATT
GGCTGTTGCTAGGAACCGTCTCAAGGCCTTATGGGCCCTGGTTACGGAAGCCGAGGAAGGCTGA
GCGCGGGCTCTCAAGGAAAGTAGTCGCGGAATCTCAGTTAGCGGTGGAGAGGCAGTATGTCCGG
TTCAATGGCGACTGCGGAAGCTAGCGGCAGCGATGGGAAAGGGCAGGAAGTCGAGACCTCAGTC
ACCTATTACCGGTTGGAGGAGGTGGCAAAGCGCAACTCCTTGAAGGAACTGTGGCTTGTGATCC
ATGGGCGAGTCTACGATGTCACCCGCTTCCTCAACGAGCACCCTGGAGGAGAAGAGGTTCTGCT
GGAACAAGCCGGTGTAGATGCAAGTGAAAGCTTTGAAGATGTAGGACACTCTTCTGATGCCAGA
GAAATGCTAAAGCAGTACTATATTGGTGATATCCATCCGAGTGACCTTAAACCTGAAAGTGGTA
GCAAGGACCCTTCAAAAAATGATACATGCAAAAGTTGCTGGGCATATTGGATTTTACCCATCAT
AGGCGCTGTTCTCTTAGGTTTCCTGTACCGCTACTACACATCGGAAAGCAAATCCTCCTGAGGA
GGCCTTGCTGAAGTTAGAAAGTGCATCCACTTTGGGGTGAAAACTAGAGACTTGCTTGGGGGCT
GCAGAAGTGCCCTCTCCTCGAATCCTGCCAGTTGCATTCTTCCCCCTTGGAGCCAAGACGATTG
GCCAGACATCACCTCAGATCTGAGACCAGCGTCTTCCATCTCTCAGAGCCTTACTCCCAAAGTA
CCTGCTCACTGTTCTGTGTTGAACAATTGCCGGTGTTTCCTCTCTTCACTGGTTTCCATGAGTA
CCCTTATATTTCACAACTTTCTGTTCATAAGTTATAGTGACATTGCTCTTTGGTAAAAATGCCT
GCTTTCCAATACTTTGATTGCATATTAGACATTCTTAACAGGGCGGCAGTCTAGTGTTGAAAGT
TTTATTTTTCCATTTTTCTTTTAAGTAAATTTTTTTTTAAAAATTCTGATTTAGGGCTAGGTGT
GGTGGCTCAGGCCTGTAATCCTGGCACTTTGGGAGGCCAAGGTGGGAAGATCACTTGAGGCCAA
GAGTTCAAGACCAGCCTGGGCAACATAGCGAGACCCCTATCTGTATTAAAAAAAAAACTGATTT
AATTCTTTTATTTATCATAAGGGGTTTAATTCCTGAAGTAAAGTTTTGCACCTATTAAACTTAA
AACTGCCAAATGATTTTTGTTCTTTTATGTGCGTGATAAAAATACAAAGAATGGTGTGGCCACC
TCCTCCCTTTCAAGCTAGGGCAGCAGGTAGCTCTTCCCACCCCCTGAGCCCAGCCCCTTCCCAA
GTGGTGCCGGACAAAAAACTACATGGCCCTTTCGTGTCTTGGGGGTGGAAAGGGAGGGATGAAT
TGGGGTGATAGAACCCTGGTGAATTCAGAGTAATCTTTCTTTAGAAAACTGGTGTTTTCTAAAG
AAACAGGATAGGAGTTTAGAGAAGGCACCAAAGCTTTCACTTTGGTTTGGCACCAGTTTCTAAC
CATCTGTTTTTTCTACCCTAGCTATCTTTTATTGGTAAAATATAAATGTATAATTATGTTTGTA
GAGCTTTACCAAGGATTTTCCCTCCTTTTTTTGTTTGTTGATTAGCAAATTTTTGATTCTCCAT
TTTCCAAAAGTAAGAGACTCCAGCATGGCCTTCTGTTTGCCCCGCAGTAAAGTAACTTCCATAT
AAAATGGTATTTGAAAGTGAGAGTTCATGACAAGAGACCGTTTTCCATTTCATCTGTATTTTAC
CTCCGTGGCTTCAACTTGTGGGTTTGTTCTGTTTTTCCATGAGAATAAAATACTGGCAGTTTTT
TTCTCAGATGTGTGTTCATTGAGAAGTAGGTTACTAGAATTATGTTACTGTGTCTTATTGGTTC
AGTGATGATTTCTCTGGCATATTAGACTTTTATTTTTTCCCCCATGGAAGCACTTGAGGAAATA
AATAGTACACTGGCTGTTTTCTGCCAGCAA

hide sequence

RefSeq Acc Id:

XM_063597703 ⟹ XP_063453773

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	78,972,035 - 79,027,929 (+)	NCBI

RefSeq Acc Id:

XM_063597704 ⟹ XP_063453774

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	18	78,972,035 - 79,027,929 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003814595	(Get FASTA)	NCBI Sequence Viewer
	XP_063453773	(Get FASTA)	NCBI Sequence Viewer
	XP_063453774	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000017140
	ENSPPAP00000017140.1
	ENSPPAP00000017154.1
	ENSPPAP00000017158.1

RefSeq Acc Id:	XP_003814595 ⟸ XM_003814547
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9AN85 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHPGGEE VLLEQAGVDASESFEDVGHSSDAREMLKQYYIGDIHPSDLKPESGSKDPSKNDTCKSCWAYWIL PIIGAVLLGFLYRYYTSESKSS hide sequence

RefSeq Acc Id:

ENSPPAP00000017140 ⟸ ENSPPAT00000039840

RefSeq Acc Id:

ENSPPAP00000017158 ⟸ ENSPPAT00000039858

RefSeq Acc Id:

ENSPPAP00000017154 ⟸ ENSPPAT00000039854

RefSeq Acc Id:	XP_063453773 ⟸ XM_063597703
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063453774 ⟸ XM_063597704
- Peptide Label:	isoform X1

Protein Domains

Cytochrome b5 heme-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000031655	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000039840.1	UniProtKB/TrEMBL
	ENSPPAT00000039854.1	UniProtKB/TrEMBL
	ENSPPAT00000039858.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.120.10	UniProtKB/TrEMBL
InterPro	Cyt_B5-like_heme/steroid-bd	UniProtKB/TrEMBL
	Cyt_B5-like_heme/steroid_sf	UniProtKB/TrEMBL
	Cyt_B5_heme-BS	UniProtKB/TrEMBL
KEGG Report	pps:100977441	UniProtKB/TrEMBL
NCBI Gene	LOC100977441	ENTREZGENE
PANTHER	CYTOCHROME B5	UniProtKB/TrEMBL
	CYTOCHROME B5 TYPE B	UniProtKB/TrEMBL
Pfam	Cyt-b5	UniProtKB/TrEMBL
PRINTS	CYTOCHROMEB5	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_B5_1	UniProtKB/TrEMBL
	CYTOCHROME_B5_2	UniProtKB/TrEMBL
SMART	Cyt-b5	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55856	UniProtKB/TrEMBL
UniProt	A0A2R9AJC4_PANPA	UniProtKB/TrEMBL
	A0A2R9AN85	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AQK1_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar