KLF2 (KLF transcription factor 2) - Rat Genome Database

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Gene: KLF2 (KLF transcription factor 2) Pan paniscus
Analyze
Symbol: KLF2
Name: KLF transcription factor 2
RGD ID: 11902619
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell morphogenesis (ortholog); cellular response to cycloheximide (ortholog); cellular response to fluid shear stress (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); COVID-19 (ortholog); lung disease (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Krueppel-like factor 2; Kruppel like factor 2; Kruppel-like factor 2 (lung)
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22021,194,451 - 21,197,283 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11920,200,667 - 20,203,238 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01915,812,506 - 15,815,244 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11916,792,497 - 16,794,143 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)
nucleus  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
KLF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22021,194,451 - 21,197,283 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11920,200,667 - 20,203,238 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01915,812,506 - 15,815,244 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11916,792,497 - 16,794,143 (+)NCBIpanpan1.1PanPan1.1panPan2
KLF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381916,324,826 - 16,328,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1916,324,826 - 16,328,685 (+)EnsemblGRCh38hg38GRCh38
GRCh371916,435,637 - 16,439,496 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,296,651 - 16,299,345 (+)NCBINCBI36Build 36hg18NCBI36
Build 341916,296,650 - 16,299,337NCBI
Celera1916,337,566 - 16,340,260 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1916,006,724 - 16,007,405 (+)NCBIHuRef
CHM1_11916,435,181 - 16,437,875 (+)NCBICHM1_1
T2T-CHM13v2.01916,459,702 - 16,463,562 (+)NCBIT2T-CHM13v2.0
Klf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39873,072,906 - 73,075,498 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl873,072,877 - 73,075,500 (+)EnsemblGRCm39 Ensembl
GRCm38872,319,062 - 72,321,654 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,319,033 - 72,321,656 (+)EnsemblGRCm38mm10GRCm38
MGSCv37874,842,961 - 74,845,553 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36875,248,022 - 75,250,338 (+)NCBIMGSCv36mm8
Celera876,656,424 - 76,659,017 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.99NCBI
Klf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81617,555,136 - 17,557,768 (-)NCBIGRCr8
mRatBN7.21617,521,107 - 17,523,739 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,514,552 - 17,523,944 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1617,587,223 - 17,589,173 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,720,530 - 18,722,483 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01617,640,143 - 17,642,093 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01619,223,087 - 19,225,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,223,087 - 19,225,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,084,196 - 19,086,146 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,941,780 - 17,943,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11617,941,777 - 17,943,728 (-)NCBI
Celera1617,739,313 - 17,741,263 (-)NCBICelera
Cytogenetic Map16p14NCBI
KLF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,182,565 - 46,183,704 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,096,492 - 46,098,925 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02046,670,279 - 46,672,712 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2046,670,789 - 46,672,713 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12045,904,933 - 45,907,365 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,316,205 - 46,318,628 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02046,591,720 - 46,594,153 (-)NCBIUU_Cfam_GSD_1.0
KLF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl261,270,199 - 61,273,138 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1261,270,733 - 61,273,037 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2260,903,997 - 60,904,625 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1614,832,013 - 14,834,744 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl614,832,029 - 14,837,462 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660744,637,274 - 4,640,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249081,021,865 - 1,023,279 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014342534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_014342534   ⟹   XP_014198020
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22021,194,451 - 21,197,283 (+)NCBI
NHGRI_mPanPan11920,200,667 - 20,203,238 (+)NCBI
Mhudiblu_PPA_v01915,812,506 - 15,815,244 (+)NCBI
PanPan1.11916,792,497 - 16,794,143 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_014198020 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_014198020   ⟸   XM_014342534
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene KLF2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-12 KLF2  KLF transcription factor 2  KLF2  Kruppel like factor 2  Symbol and/or name change 5135510 APPROVED