DNPH1 (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) - Rat Genome Database

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Gene: DNPH1 (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) Pan paniscus
Analyze
Symbol: DNPH1
Name: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
RGD ID: 11900871
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN allantoin metabolic process (ortholog); dGMP catabolic process (ortholog); epithelial cell differentiation (ortholog); ASSOCIATED WITH infantile Refsum disease (ortholog); Zellweger syndrome (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 5-hydroxymethyl-dUMP N-hydrolase; deoxyribonucleoside 5'-monophosphate N-glycosidase-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,725,535 - 57,729,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,595,338 - 53,599,201 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,817,392 - 42,821,257 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1644,111,148 - 44,111,975 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DNPH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,725,535 - 57,729,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,595,338 - 53,599,201 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,817,392 - 42,821,257 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1644,111,148 - 44,111,975 (-)NCBIpanpan1.1PanPan1.1panPan2
DNPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,225,629 - 43,229,481 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,225,629 - 43,229,481 (-)EnsemblGRCh38hg38GRCh38
GRCh37643,193,367 - 43,197,219 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,301,345 - 43,305,189 (-)NCBINCBI36Build 36hg18NCBI36
Celera644,745,576 - 44,749,420 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,910,063 - 42,913,907 (-)NCBIHuRef
CHM1_1643,196,302 - 43,200,146 (-)NCBICHM1_1
T2T-CHM13v2.0643,054,425 - 43,058,274 (-)NCBIT2T-CHM13v2.0
Dnph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,807,715 - 46,810,544 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,807,637 - 46,810,550 (+)EnsemblGRCm39 Ensembl
GRCm381746,496,789 - 46,499,618 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,496,711 - 46,499,624 (+)EnsemblGRCm38mm10GRCm38
MGSCv371746,633,738 - 46,636,567 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,959,989 - 45,962,263 (+)NCBIMGSCv36mm8
Celera1749,932,506 - 49,935,335 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Dnph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,978,894 - 21,981,631 (-)NCBIGRCr8
mRatBN7.2914,481,296 - 14,484,034 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,481,066 - 14,484,022 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,064,957 - 23,067,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0928,127,963 - 28,130,702 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,428,337 - 26,431,069 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,845,764 - 16,848,514 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,845,525 - 16,848,503 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,747,108 - 15,749,858 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,865,096 - 9,867,833 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.199,862,418 - 9,865,155 (-)NCBI
Celera912,229,311 - 12,232,048 (-)NCBICelera
Cytogenetic Map9q12NCBI
Dnph1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,145,737 - 9,147,387 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,145,737 - 9,147,388 (-)NCBIChiLan1.0ChiLan1.0
DNPH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,715,215 - 11,718,622 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,715,271 - 11,718,717 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,741,713 - 11,745,559 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,197,074 - 12,200,947 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,197,609 - 12,201,457 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,724,395 - 11,728,261 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,808,785 - 11,812,597 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,903,616 - 11,907,485 (-)NCBIUU_Cfam_GSD_1.0
Dnph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,217,364 - 47,219,582 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,740,581 - 16,742,866 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,740,643 - 16,742,831 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNPH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,263,822 - 38,266,887 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,263,819 - 38,267,361 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,764,179 - 43,767,693 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNPH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11728,923,202 - 28,927,227 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604443,287,459 - 43,291,712 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnph1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,333,054 - 16,334,882 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,333,021 - 16,334,882 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034962124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_034962124   ⟹   XP_034818015
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,725,535 - 57,729,459 (-)NCBI
NHGRI_mPanPan1653,595,338 - 53,599,201 (-)NCBI
Mhudiblu_PPA_v0642,817,392 - 42,821,257 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034818015 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000033381.1
Reference Protein Sequences
RefSeq Acc Id: XP_034818015   ⟸   XM_034962124


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039553 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056256.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.450 UniProtKB/TrEMBL
InterPro DNPH1 UniProtKB/TrEMBL
  Nucleoside_deoxyribTrfase UniProtKB/TrEMBL
NCBI Gene DNPH1 ENTREZGENE
PANTHER 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 UniProtKB/TrEMBL
  2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 UniProtKB/TrEMBL
Pfam Nuc_deoxyrib_tr UniProtKB/TrEMBL
Superfamily-SCOP N-(deoxy)ribosyltransferase-like UniProtKB/TrEMBL
UniProt A0A2R9BV92_PANPA UniProtKB/TrEMBL