RELB (RELB proto-oncogene, NF-kB subunit) - Rat Genome Database

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Gene: RELB (RELB proto-oncogene, NF-kB subunit) Pan paniscus
Analyze
Symbol: RELB
Name: RELB proto-oncogene, NF-kB subunit
RGD ID: 11897512
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN antigen processing and presentation (ortholog); cellular response to osmotic stress (ortholog); myeloid dendritic cell differentiation (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); atopic dermatitis (ortholog); breast cancer (ortholog); FOUND IN nucleus (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor RelB; v-rel reticuloendotheliosis viral oncogene homolog B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,160,728 - 51,199,294 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,032,147 - 53,070,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,948,559 - 41,987,121 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,563,164 - 50,590,627 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,554,864 - 50,590,223 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RELB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,160,728 - 51,199,294 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,032,147 - 53,070,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,948,559 - 41,987,121 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,563,164 - 50,590,627 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,554,864 - 50,590,223 (+)Ensemblpanpan1.1panPan2
RELB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,001,464 - 45,038,192 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,001,461 - 45,038,192 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,504,722 - 45,541,450 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,196,552 - 50,233,292 (+)NCBINCBI36Build 36hg18NCBI36
Build 341950,196,551 - 50,233,292NCBI
Celera1942,309,022 - 42,345,751 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1941,935,689 - 41,971,666 (+)NCBIHuRef
CHM1_11945,507,785 - 45,544,777 (+)NCBICHM1_1
T2T-CHM13v2.01947,826,284 - 47,863,291 (+)NCBIT2T-CHM13v2.0
Relb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,340,142 - 19,363,352 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,340,142 - 19,363,363 (-)EnsemblGRCm39 Ensembl
GRCm38719,606,217 - 19,629,438 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,606,217 - 19,629,438 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,191,571 - 20,214,787 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,764,744 - 18,787,960 (-)NCBIMGSCv36mm8
Celera717,011,812 - 17,035,368 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.93NCBI
Relb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,385,717 - 88,413,380 (-)NCBIGRCr8
mRatBN7.2179,257,738 - 79,285,490 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,257,725 - 79,285,507 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0180,517,081 - 80,545,019 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,517,411 - 80,544,825 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,783,102 - 81,810,793 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera173,717,263 - 73,744,749 (-)NCBICelera
Cytogenetic Map1q21NCBI
Relb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555552,060,533 - 2,086,229 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555552,060,533 - 2,086,229 (+)NCBIChiLan1.0ChiLan1.0
RELB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,436,677 - 110,466,709 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,436,662 - 110,466,809 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,917,954 - 109,947,957 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,966,408 - 110,996,642 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,966,393 - 110,996,550 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,641,652 - 110,671,422 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,277,051 - 110,306,823 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,145,641 - 111,175,691 (-)NCBIUU_Cfam_GSD_1.0
Relb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,222,260 - 17,249,483 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,569,756 - 1,596,456 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,569,603 - 1,596,831 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RELB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,444,664 - 51,480,319 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,444,670 - 51,480,350 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RELB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,463,414 - 38,500,487 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607318,045,037 - 18,087,099 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Relb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,806,874 - 1,829,417 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249071,806,784 - 1,829,686 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000038361   ⟹   ENSPPAP00000015670
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1950,554,864 - 50,590,223 (+)Ensembl
RefSeq Acc Id: XM_034945009   ⟹   XP_034800900
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22051,160,728 - 51,199,294 (+)NCBI
NHGRI_mPanPan11953,032,147 - 53,070,712 (+)NCBI
Mhudiblu_PPA_v01941,948,568 - 41,987,121 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034800900 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000015670.1
RefSeq Acc Id: XP_034800900   ⟸   XM_034945009
- UniProtKB: A0A2R9AED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000015670   ⟸   ENSPPAT00000038361
Protein Domains
RHD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030963 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038361.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  2.60.40.340 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  IPT_NFkappaB UniProtKB/TrEMBL
  NFkB/Dor UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/TrEMBL
  RelB UniProtKB/TrEMBL
  RelB_leu_zip UniProtKB/TrEMBL
  RelB_transact UniProtKB/TrEMBL
  RHD_CS UniProtKB/TrEMBL
  RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind_dom UniProtKB/TrEMBL
  RHD_DNA_bind_dom_sf UniProtKB/TrEMBL
NCBI Gene RELB ENTREZGENE
PANTHER PTHR24169 UniProtKB/TrEMBL
  PTHR24169:SF18 UniProtKB/TrEMBL
Pfam RelB_leu_zip UniProtKB/TrEMBL
  RelB_transactiv UniProtKB/TrEMBL
  RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind UniProtKB/TrEMBL
PRINTS NFKBTNSCPFCT UniProtKB/TrEMBL
PROSITE REL_1 UniProtKB/TrEMBL
  REL_2 UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A2R9AED0 ENTREZGENE, UniProtKB/TrEMBL