TCL1B (TCL1 family AKT coactivator B) - Rat Genome Database

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Gene: TCL1B (TCL1 family AKT coactivator B) Pan paniscus
Analyze
Symbol: TCL1B
Name: TCL1 family AKT coactivator B
RGD ID: 11874366
Description: ENCODES a protein that exhibits protein kinase binding (inferred); protein serine/threonine kinase activator activity (inferred); INVOLVED IN intracellular signal transduction (inferred); positive regulation of peptidyl-serine phosphorylation (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Neoplasm Metastasis (ortholog); Parkinson's disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T cell leukemia/lymphoma 1B; T-cell leukemia/lymphoma 1B; T-cell leukemia/lymphoma protein 1B
RGD Orthologs
Human
Mouse
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21596,842,185 - 96,847,026 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11496,058,650 - 96,064,573 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01476,315,855 - 76,322,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11495,639,798 - 95,645,999 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1495,639,798 - 95,645,999 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TCL1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21596,842,185 - 96,847,026 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11496,058,650 - 96,064,573 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01476,315,855 - 76,322,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11495,639,798 - 95,645,999 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1495,639,798 - 95,645,999 (+)Ensemblpanpan1.1panPan2
TCL1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381495,686,426 - 95,692,628 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1495,686,426 - 95,692,628 (+)EnsemblGRCh38hg38GRCh38
GRCh371496,152,763 - 96,158,965 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361495,222,516 - 95,228,720 (+)NCBINCBI36Build 36hg18NCBI36
Build 341495,222,515 - 95,228,719NCBI
Celera1476,208,508 - 76,214,717 (+)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1476,338,317 - 76,344,548 (+)NCBIHuRef
CHM1_11496,090,663 - 96,096,959 (+)NCBICHM1_1
T2T-CHM13v2.01489,918,003 - 89,924,209 (+)NCBIT2T-CHM13v2.0
Tcl1b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912105,125,963 - 105,132,884 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12105,125,949 - 105,132,884 (+)EnsemblGRCm39 Ensembl
GRCm3812105,159,704 - 105,166,625 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12105,159,690 - 105,166,625 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712106,397,914 - 106,404,835 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612105,560,754 - 105,567,675 (+)NCBIMGSCv36mm8
Celera12106,392,293 - 106,399,180 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1255.21NCBI
TCL1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1864,497,560 - 64,500,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl864,497,560 - 64,500,412 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha864,076,224 - 64,079,263 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0864,766,393 - 64,769,248 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl864,766,393 - 64,769,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1864,440,626 - 64,443,479 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0864,501,936 - 64,504,788 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0864,825,329 - 64,828,387 (+)NCBIUU_Cfam_GSD_1.0
Tcl1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086409,999,209 - 10,004,227 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493660478,241 - 83,259 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCL1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7116,912,976 - 116,917,934 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17116,912,974 - 116,917,940 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27124,127,971 - 124,132,982 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TCL1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12473,548,086 - 73,554,048 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2473,548,165 - 73,552,726 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605360,717,114 - 60,722,999 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047612   ⟹   ENSPPAP00000024787
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1495,639,798 - 95,645,999 (+)Ensembl
RefSeq Acc Id: XM_057299782   ⟹   XP_057155765
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21596,842,185 - 96,847,026 (+)NCBI
NHGRI_mPanPan11496,058,650 - 96,064,573 (+)NCBI
Protein Sequences
Protein RefSeqs XP_057155765 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024787.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000024787   ⟸   ENSPPAT00000047612
RefSeq Acc Id: XP_057155765   ⟸   XM_057299782
- UniProtKB: A0A2R9B5B6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035530 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047612.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.15.10 UniProtKB/TrEMBL
InterPro TCL1_MTCP1 UniProtKB/TrEMBL
  TCL1_MTCP1_sf UniProtKB/TrEMBL
KEGG Report pps:100970085 UniProtKB/TrEMBL
NCBI Gene TCL1B ENTREZGENE
PANTHER PTHR14060 UniProtKB/TrEMBL
  T-CELL LEUKEMIA/LYMPHOMA PROTEIN 1B UniProtKB/TrEMBL
Pfam TCL1_MTCP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF50904 UniProtKB/TrEMBL
UniProt A0A2R9B5B6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-05-05 TCL1B  TCL1 family AKT coactivator B  TCL1B  T cell leukemia/lymphoma 1B  Symbol and/or name change 5135510 APPROVED
2017-12-19 TCL1B  T cell leukemia/lymphoma 1B    T-cell leukemia/lymphoma 1B  Symbol and/or name change 5135510 APPROVED