SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1) - Rat Genome Database

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Gene: SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1) Pan paniscus
Analyze
Symbol: SH3GLB1
Name: SH3 domain containing GRB2 like, endophilin B1
RGD ID: 11867100
Description: ENCODES a protein that exhibits fatty acid binding (ortholog); lysophosphatidic acid acyltransferase activity (ortholog); phosphatidylinositol 3-kinase activator activity (ortholog); INVOLVED IN 'de novo' post-translational protein folding (ortholog); apoptotic process (ortholog); mitochondrion organization (ortholog); PARTICIPATES IN mitochondria fission pathway; FOUND IN early endosome (ortholog); neuronal cell body (ortholog); synaptic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: endophilin-B1; SH3 domain containing GRB2 like endophilin B1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21140,227,422 - 140,266,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11139,378,255 - 139,421,980 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,224,304 - 119,267,986 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1188,077,401 - 88,121,056 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl188,077,420 - 88,121,056 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SH3GLB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21140,227,422 - 140,266,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11139,378,255 - 139,421,980 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,224,304 - 119,267,986 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1188,077,401 - 88,121,056 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl188,077,420 - 88,121,056 (+)Ensemblpanpan1.1panPan2
SH3GLB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38186,704,576 - 86,748,184 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl186,704,570 - 86,748,184 (+)EnsemblGRCh38hg38GRCh38
GRCh37187,170,259 - 87,213,867 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36186,942,845 - 86,986,455 (+)NCBINCBI36Build 36hg18NCBI36
Build 34186,882,524 - 86,921,290NCBI
Celera185,413,638 - 85,457,246 (+)NCBICelera
Cytogenetic Map1p22.3NCBI
HuRef185,280,855 - 85,324,463 (+)NCBIHuRef
CHM1_1187,285,087 - 87,328,713 (+)NCBICHM1_1
T2T-CHM13v2.0186,544,605 - 86,588,211 (+)NCBIT2T-CHM13v2.0
Sh3glb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393144,389,426 - 144,426,186 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3144,389,439 - 144,426,096 (-)EnsemblGRCm39 Ensembl
GRCm383144,683,665 - 144,720,408 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3144,683,678 - 144,720,335 (-)EnsemblGRCm38mm10GRCm38
MGSCv373144,351,808 - 144,383,287 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363144,626,230 - 144,657,709 (-)NCBIMGSCv36mm8
Celera3151,130,849 - 151,162,252 (-)NCBICelera
Cytogenetic Map3H2NCBI
cM Map369.0NCBI
Sh3glb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82236,411,194 - 236,445,225 (-)NCBIGRCr8
mRatBN7.22233,750,838 - 233,784,817 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2233,750,838 - 233,784,784 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2241,542,137 - 241,570,014 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02239,436,138 - 239,464,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02234,299,748 - 234,327,625 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02250,709,812 - 250,744,216 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2250,709,439 - 250,744,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02269,236,633 - 269,271,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42242,874,678 - 242,903,467 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12242,861,417 - 242,890,207 (-)NCBI
Celera2225,746,540 - 225,774,430 (-)NCBICelera
Cytogenetic Map2q44NCBI
Sh3glb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554237,393,186 - 7,423,903 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554237,393,186 - 7,414,199 (-)NCBIChiLan1.0ChiLan1.0
SH3GLB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1661,439,414 - 61,471,414 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl661,439,415 - 61,462,087 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha664,153,405 - 64,186,410 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0661,979,099 - 62,012,117 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl661,974,692 - 62,011,837 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1661,512,632 - 61,545,627 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0661,475,720 - 61,508,706 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0661,974,409 - 62,007,415 (-)NCBIUU_Cfam_GSD_1.0
Sh3glb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505897,341,464 - 97,372,308 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367322,067,204 - 2,097,631 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367322,066,848 - 2,097,947 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3GLB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4129,357,552 - 129,395,583 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14129,361,596 - 129,395,790 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24141,809,640 - 141,843,706 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH3GLB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12046,707,556 - 46,746,785 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2046,707,910 - 46,746,735 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603371,094,700 - 71,138,519 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3glb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474210,845,333 - 10,883,705 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000051857   ⟹   ENSPPAP00000029009
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl188,077,420 - 88,121,056 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000051859   ⟹   ENSPPAP00000029011
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl188,077,420 - 88,121,056 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000051868   ⟹   ENSPPAP00000029020
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl188,077,432 - 88,121,056 (+)Ensembl
RefSeq Acc Id: XM_003805304   ⟹   XP_003805352
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,499 (-)NCBI
NHGRI_mPanPan11139,378,255 - 139,421,980 (-)NCBI
Mhudiblu_PPA_v01119,224,310 - 119,267,986 (+)NCBI
PanPan1.1188,077,425 - 88,121,056 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003805305   ⟹   XP_003805353
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,327 (-)NCBI
NHGRI_mPanPan11139,378,255 - 139,421,667 (-)NCBI
Mhudiblu_PPA_v01119,224,310 - 119,267,986 (+)NCBI
PanPan1.1188,077,401 - 88,121,056 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008969647   ⟹   XP_008967895
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,517 (-)NCBI
NHGRI_mPanPan11139,378,255 - 139,421,777 (-)NCBI
Mhudiblu_PPA_v01119,224,324 - 119,263,384 (+)NCBI
PanPan1.1188,077,401 - 88,121,056 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055116526   ⟹   XP_054972501
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,327 (-)NCBI
NHGRI_mPanPan11139,378,255 - 139,421,667 (-)NCBI
RefSeq Acc Id: XM_055116529   ⟹   XP_054972504
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,327 (-)NCBI
NHGRI_mPanPan11139,378,255 - 139,421,667 (-)NCBI
RefSeq Acc Id: XM_055116537   ⟹   XP_054972512
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,327 (-)NCBI
NHGRI_mPanPan11139,378,255 - 139,421,667 (-)NCBI
RefSeq Acc Id: XM_063607057   ⟹   XP_063463127
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21140,227,422 - 140,266,327 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003805353   ⟸   XM_003805305
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BQX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003805352   ⟸   XM_003805304
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BH85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008967895   ⟸   XM_008969647
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSPPAP00000029011   ⟸   ENSPPAT00000051859
RefSeq Acc Id: ENSPPAP00000029009   ⟸   ENSPPAT00000051857
RefSeq Acc Id: ENSPPAP00000029020   ⟸   ENSPPAT00000051868
RefSeq Acc Id: XP_054972512   ⟸   XM_055116537
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054972504   ⟸   XM_055116529
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054972501   ⟸   XM_055116526
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063463127   ⟸   XM_063607057
- Peptide Label: isoform X7
Protein Domains
BAR   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037511 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051857.1 UniProtKB/TrEMBL
  ENSPPAT00000051859.1 UniProtKB/TrEMBL
  ENSPPAT00000051868.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  BAR_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SH3GLB1_BAR UniProtKB/TrEMBL
  SH3GLB_SH3 UniProtKB/TrEMBL
KEGG Report pps:100982561 UniProtKB/TrEMBL
NCBI Gene SH3GLB1 ENTREZGENE
PANTHER PTHR14167:SF52 UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam BAR UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE BAR UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART BAR UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A2R9BH81_PANPA UniProtKB/TrEMBL
  A0A2R9BH85 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BQX2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-28 SH3GLB1  SH3 domain containing GRB2 like, endophilin B1    SH3 domain containing GRB2 like endophilin B1  Symbol and/or name change 5135510 APPROVED