TBC1D4 (TBC1 domain family member 4) - Rat Genome Database

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Gene: TBC1D4 (TBC1 domain family member 4) Pan paniscus
Analyze
Symbol: TBC1D4
Name: TBC1 domain family member 4
RGD ID: 11847690
Description: INVOLVED IN cellular response to insulin stimulus (ortholog); negative regulation of vesicle fusion (ortholog); PARTICIPATES IN altered insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH acanthosis nigricans (ortholog); chromosome 13q14 deletion syndrome (ortholog); Congenital Hyperinsulinism (ortholog); FOUND IN vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21476,864,486 - 77,058,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11375,457,938 - 75,656,273 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01356,513,065 - 56,706,491 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11375,282,441 - 75,480,138 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1375,282,441 - 75,361,729 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
vesicle  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
TBC1D4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21476,864,486 - 77,058,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11375,457,938 - 75,656,273 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01356,513,065 - 56,706,491 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11375,282,441 - 75,480,138 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1375,282,441 - 75,361,729 (-)Ensemblpanpan1.1panPan2
TBC1D4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381375,283,503 - 75,482,169 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1375,283,503 - 75,482,169 (-)EnsemblGRCh38hg38GRCh38
GRCh371375,857,639 - 76,056,305 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361374,756,810 - 74,954,251 (-)NCBINCBI36Build 36hg18NCBI36
Build 341374,757,253 - 74,954,251NCBI
Celera1356,756,694 - 56,954,119 (-)NCBICelera
Cytogenetic Map13q22.2NCBI
HuRef1356,556,159 - 56,753,666 (-)NCBIHuRef
CHM1_11375,826,535 - 76,023,986 (-)NCBICHM1_1
T2T-CHM13v2.01374,507,182 - 74,705,799 (-)NCBIT2T-CHM13v2.0
Tbc1d4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914101,679,800 - 101,846,717 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14101,679,796 - 101,846,627 (-)EnsemblGRCm39 Ensembl
GRCm3814101,442,360 - 101,609,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14101,442,360 - 101,609,191 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714101,841,577 - 102,008,408 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614100,325,233 - 100,494,965 (-)NCBIMGSCv36mm8
Celera14100,079,886 - 100,248,354 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1450.9NCBI
Tbc1d4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81584,670,756 - 84,848,876 (-)NCBIGRCr8
mRatBN7.21578,256,030 - 78,434,168 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1578,257,121 - 78,434,265 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01585,927,978 - 86,105,829 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1585,930,044 - 86,105,273 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01589,695,614 - 89,871,879 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41585,359,159 - 85,561,229 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1577,452,014 - 77,628,396 (-)NCBICelera
Cytogenetic Map15q21NCBI
Tbc1d4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540431,622,102 - 31,691,517 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540431,516,727 - 31,691,414 (+)NCBIChiLan1.0ChiLan1.0
TBC1D4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12229,109,079 - 29,175,357 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2229,110,201 - 29,290,154 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2228,971,148 - 29,151,992 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02229,444,745 - 29,625,974 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2229,445,331 - 29,625,959 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12229,095,512 - 29,277,006 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02229,139,459 - 29,320,685 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02229,208,132 - 29,388,931 (-)NCBIUU_Cfam_GSD_1.0
Tbc1d4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945130,255,477 - 130,441,705 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365115,673,368 - 5,856,631 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365115,789,683 - 5,858,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1147,543,815 - 47,828,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11147,543,808 - 47,760,928 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21152,161,139 - 52,187,164 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1354,384,597 - 54,588,842 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl354,386,342 - 54,464,531 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604610,524,400 - 10,732,251 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475124,999,386 - 25,181,702 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475124,999,301 - 25,183,905 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000061478   ⟹   ENSPPAP00000038574
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1375,282,441 - 75,360,159 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000061494   ⟹   ENSPPAP00000038590
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1375,284,559 - 75,361,729 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000061498   ⟹   ENSPPAP00000038594
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1375,284,559 - 75,361,729 (-)Ensembl
RefSeq Acc Id: XM_014347449   ⟹   XP_014202935
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21476,864,486 - 77,058,341 (-)NCBI
NHGRI_mPanPan11375,457,938 - 75,656,273 (-)NCBI
Mhudiblu_PPA_v01356,513,065 - 56,706,491 (-)NCBI
PanPan1.11375,282,441 - 75,480,138 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063595792   ⟹   XP_063451862
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21476,864,486 - 77,058,299 (-)NCBI
Protein Sequences
Protein RefSeqs XP_014202935 (Get FASTA)   NCBI Sequence Viewer  
  XP_063451862 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038574.1
  ENSPPAP00000038590.1
  ENSPPAP00000038594.1
Reference Protein Sequences
RefSeq Acc Id: XP_014202935   ⟸   XM_014347449
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C9R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000038590   ⟸   ENSPPAT00000061494
RefSeq Acc Id: ENSPPAP00000038594   ⟸   ENSPPAT00000061498
RefSeq Acc Id: ENSPPAP00000038574   ⟸   ENSPPAT00000061478
RefSeq Acc Id: XP_063451862   ⟸   XM_063595792
- Peptide Label: isoform X2
Protein Domains
PID   Rab-GAP TBC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041970 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061478.1 UniProtKB/TrEMBL
  ENSPPAT00000061494.1 UniProtKB/TrEMBL
  ENSPPAT00000061498.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2750 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro DUF3350 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
  Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
NCBI Gene TBC1D4 ENTREZGENE
PANTHER RAB GTPASE-ACTIVATING PROTEIN 1-LIKE UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER 4 ISOFORM X1 UniProtKB/TrEMBL
Pfam DUF3350 UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
  RabGAP-TBC UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47923 UniProtKB/TrEMBL
UniProt A0A2R9C9G5_PANPA UniProtKB/TrEMBL
  A0A2R9C9P6_PANPA UniProtKB/TrEMBL
  A0A2R9C9R5 ENTREZGENE, UniProtKB/TrEMBL