EEF2K (eukaryotic elongation factor 2 kinase) - Rat Genome Database

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Gene: EEF2K (eukaryotic elongation factor 2 kinase) Pan paniscus
Analyze
Symbol: EEF2K
Name: eukaryotic elongation factor 2 kinase
RGD ID: 11834130
Description: ENCODES a protein that exhibits elongation factor-2 kinase activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); autistic disorder (ortholog); chromosome 16p12.1 deletion syndrome (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21823,051,125 - 23,133,784 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11627,571,678 - 27,654,230 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01616,443,579 - 16,526,061 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11622,518,150 - 22,598,735 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1622,537,518 - 22,596,091 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EEF2K
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21823,051,125 - 23,133,784 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11627,571,678 - 27,654,230 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01616,443,579 - 16,526,061 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11622,518,150 - 22,598,735 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1622,537,518 - 22,596,091 (+)Ensemblpanpan1.1panPan2
EEF2K
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381622,206,278 - 22,288,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1622,206,278 - 22,288,738 (+)EnsemblGRCh38hg38GRCh38
GRCh371622,217,599 - 22,300,059 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361622,125,093 - 22,207,567 (+)NCBINCBI36Build 36hg18NCBI36
Build 341622,125,256 - 22,205,452NCBI
Celera1620,997,480 - 21,079,953 (+)NCBICelera
Cytogenetic Map16p12.2NCBI
HuRef1620,462,336 - 20,544,660 (+)NCBIHuRef
CHM1_11622,091,272 - 22,173,735 (-)NCBICHM1_1
T2T-CHM13v2.01621,928,475 - 22,010,936 (-)NCBIT2T-CHM13v2.0
Eef2k
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397120,442,080 - 120,506,441 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7120,442,054 - 120,506,673 (+)EnsemblGRCm39 Ensembl
GRCm387120,842,642 - 120,907,219 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7120,842,831 - 120,907,450 (+)EnsemblGRCm38mm10GRCm38
MGSCv377127,986,397 - 128,047,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367120,634,032 - 120,695,150 (+)NCBIMGSCv36mm8
Celera7120,755,613 - 120,816,599 (+)NCBICelera
Cytogenetic Map7F2NCBI
cM Map764.95NCBI
Eef2k
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81184,824,420 - 184,888,048 (+)NCBIGRCr8
mRatBN7.21175,393,119 - 175,456,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1175,393,154 - 175,455,164 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1183,753,768 - 183,794,993 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01190,939,743 - 190,980,965 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,625,310 - 183,666,539 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01190,780,211 - 190,839,926 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1190,780,236 - 190,842,324 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01197,704,669 - 197,766,058 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,712,404 - 179,754,345 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11179,832,738 - 179,895,924 (+)NCBI
Celera1173,143,531 - 173,184,040 (+)NCBICelera
Cytogenetic Map1q36NCBI
Eef2k
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955493865,830 - 922,765 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955493865,830 - 922,765 (+)NCBIChiLan1.0ChiLan1.0
EEF2K
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1623,368,296 - 23,433,853 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl623,371,546 - 23,433,929 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha624,863,141 - 24,928,560 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0623,506,671 - 23,572,566 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl623,506,218 - 23,572,676 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1623,308,900 - 23,374,695 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0623,218,207 - 23,280,831 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0623,600,299 - 23,665,719 (-)NCBIUU_Cfam_GSD_1.0
Eef2k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344119,053,057 - 119,105,538 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365017,160,134 - 7,207,377 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365017,160,134 - 7,205,231 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EEF2K
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl323,887,125 - 23,956,373 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1323,887,120 - 23,980,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2324,287,297 - 24,412,626 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EEF2K
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1519,871,669 - 19,957,471 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl519,871,310 - 19,957,395 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660689,911,761 - 9,997,341 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eef2k
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,606,655 - 7,666,206 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,606,576 - 7,668,771 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000052010   ⟹   ENSPPAP00000029162
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1622,537,518 - 22,596,091 (+)Ensembl
RefSeq Acc Id: XM_034939879   ⟹   XP_034795770
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21823,051,125 - 23,133,784 (+)NCBI
NHGRI_mPanPan11627,571,678 - 27,654,230 (+)NCBI
Mhudiblu_PPA_v01616,443,579 - 16,526,061 (-)NCBI
RefSeq Acc Id: XM_034939880   ⟹   XP_034795771
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21823,051,191 - 23,133,784 (+)NCBI
NHGRI_mPanPan11627,581,112 - 27,654,230 (+)NCBI
Mhudiblu_PPA_v01616,444,481 - 16,511,609 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034795770 (Get FASTA)   NCBI Sequence Viewer  
  XP_034795771 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000029162.1
Reference Protein Sequences
RefSeq Acc Id: XP_034795770   ⟸   XM_034939879
- UniProtKB: A0A2R9BL84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034795771   ⟸   XM_034939880
- UniProtKB: A0A2R9BL84 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000029162   ⟸   ENSPPAT00000052010
Protein Domains
Alpha-type protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037581 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052010.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  MHCK/EF2 kinase UniProtKB/TrEMBL
InterPro eEF-2K UniProtKB/TrEMBL
  eEF2K_a_kinase_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
  Sel1-like UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene EEF2K ENTREZGENE
PANTHER EUKARYOTIC ELONGATION FACTOR 2 KINASE UniProtKB/TrEMBL
  EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
  Sel1 UniProtKB/TrEMBL
PIRSF Elongation_factor_2_kinase UniProtKB/TrEMBL
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
SMART Alpha_kinase UniProtKB/TrEMBL
Superfamily-SCOP HCP-like UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9BL84 ENTREZGENE, UniProtKB/TrEMBL