EGR4 (early growth response 4) - Rat Genome Database

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Gene: EGR4 (early growth response 4) Pan paniscus
Analyze
Symbol: EGR4
Name: early growth response 4
RGD ID: 11824700
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to growth factor stimulus (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Alstrom syndrome (ortholog); congenital disorder of glycosylation type IIb (ortholog); dystonia (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: early growth response protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21253,087,182 - 53,089,822 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A53,089,935 - 53,092,572 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,343,705 - 73,346,476 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A74,831,326 - 74,834,246 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,831,326 - 74,834,246 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EGR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21253,087,182 - 53,089,822 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A53,089,935 - 53,092,572 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,343,705 - 73,346,476 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A74,831,326 - 74,834,246 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,831,326 - 74,834,246 (-)Ensemblpanpan1.1panPan2
EGR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,290,929 - 73,293,548 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,290,929 - 73,293,701 (-)EnsemblGRCh38hg38GRCh38
GRCh37273,518,057 - 73,520,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,371,565 - 73,374,181 (-)NCBINCBI36Build 36hg18NCBI36
Build 34273,429,720 - 73,432,265NCBI
Celera273,368,884 - 73,371,656 (-)NCBICelera
Cytogenetic Map2p13.2NCBI
HuRef273,253,506 - 73,256,278 (-)NCBIHuRef
CHM1_1273,448,863 - 73,451,635 (-)NCBICHM1_1
T2T-CHM13v2.0273,300,923 - 73,306,546 (-)NCBIT2T-CHM13v2.0
Egr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,488,103 - 85,490,571 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,488,103 - 85,490,571 (-)EnsemblGRCm39 Ensembl
GRCm38685,511,121 - 85,513,589 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,511,121 - 85,513,589 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,461,116 - 85,463,536 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36685,476,780 - 85,479,200 (-)NCBIMGSCv36mm8
Celera687,483,061 - 87,485,363 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.48NCBI
Egr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,605,358 - 119,607,817 (-)NCBIGRCr8
mRatBN7.24118,047,869 - 118,050,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4118,047,869 - 118,050,328 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4123,529,269 - 123,531,728 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,304,376 - 119,306,835 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04117,917,863 - 117,920,322 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,293,620 - 117,296,082 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,293,620 - 117,296,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,870,041 - 181,872,503 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,765,289 - 119,767,612 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14120,009,769 - 120,012,093 (-)NCBI
Celera4107,029,479 - 107,031,938 (-)NCBICelera
RH 3.4 Map4690.8RGD
Cytogenetic Map4q34NCBI
Egr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,338,979 - 12,342,078 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,339,152 - 12,341,925 (+)NCBIChiLan1.0ChiLan1.0
EGR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,575,964 - 49,580,697 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,575,466 - 49,578,251 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1749,222,642 - 49,225,616 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01750,441,901 - 50,444,875 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1750,441,953 - 50,444,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11749,458,229 - 49,461,203 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,524,903 - 49,527,877 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01750,084,062 - 50,087,036 (+)NCBIUU_Cfam_GSD_1.0
Egr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,499,683 - 11,502,500 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649117,069,325 - 17,071,226 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649117,068,797 - 17,071,608 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EGR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,485,949 - 69,488,975 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,485,919 - 69,488,788 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,688,741 - 72,691,610 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EGR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,879,707 - 33,882,669 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1433,879,904 - 33,882,663 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604578,196,090 - 78,203,083 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Egr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624762351,600 - 353,449 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624762351,190 - 354,004 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000045675   ⟹   ENSPPAP00000022861
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A74,831,326 - 74,834,246 (-)Ensembl
RefSeq Acc Id: XM_003808201   ⟹   XP_003808249
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21253,087,182 - 53,089,822 (+)NCBI
NHGRI_mPanPan12A53,089,935 - 53,092,572 (+)NCBI
Mhudiblu_PPA_v02A73,343,705 - 73,346,343 (-)NCBI
PanPan1.12A74,831,328 - 74,834,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008960290   ⟹   XP_008958538
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21253,087,182 - 53,089,822 (+)NCBI
NHGRI_mPanPan12A53,089,935 - 53,092,572 (+)NCBI
Mhudiblu_PPA_v02A73,343,705 - 73,346,476 (-)NCBI
PanPan1.12A74,831,326 - 74,834,246 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003808249 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958538 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000022861.1
RefSeq Acc Id: XP_008958538   ⟸   XM_008960290
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B6C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003808249   ⟸   XM_003808201
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B6C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000022861   ⟸   ENSPPAT00000045675
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034601 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045675.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene EGR4 ENTREZGENE
PANTHER EARLY GROWTH RESPONSE PROTEIN 4 UniProtKB/TrEMBL
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A2R9B6C1 ENTREZGENE, UniProtKB/TrEMBL