RIT1 (Ras like without CAAX 1) - Rat Genome Database

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Gene: RIT1 (Ras like without CAAX 1) Pan paniscus
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Symbol: RIT1
Name: Ras like without CAAX 1
RGD ID: 11823544
Description: ENCODES a protein that exhibits calmodulin binding (inferred); GDP binding (inferred); GTP binding (inferred); INVOLVED IN Ras protein signal transduction (inferred); signal transduction (inferred); ASSOCIATED WITH cardiofaciocutaneous syndrome (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); cherubism (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GTP-binding protein Rit1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,943,872 - 93,973,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,674,831 - 93,704,667 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,232,277 - 131,245,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,062,994 - 135,075,183 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,063,000 - 135,074,942 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,943,872 - 93,973,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,674,831 - 93,704,667 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,232,277 - 131,245,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,062,994 - 135,075,183 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,063,000 - 135,074,942 (-)Ensemblpanpan1.1panPan2
RIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381155,897,808 - 155,911,349 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1155,897,808 - 155,911,404 (-)EnsemblGRCh38hg38GRCh38
GRCh371155,867,599 - 155,881,140 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,134,225 - 154,147,801 (-)NCBINCBI36Build 36hg18NCBI36
Build 341152,682,962 - 152,694,199NCBI
Celera1128,940,503 - 128,954,081 (-)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1127,228,453 - 127,242,067 (-)NCBIHuRef
CHM1_11157,263,378 - 157,276,968 (-)NCBICHM1_1
T2T-CHM13v2.01155,035,925 - 155,049,482 (-)NCBIT2T-CHM13v2.0
Rit1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,624,154 - 88,638,354 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,624,145 - 88,638,356 (+)EnsemblGRCm39 Ensembl
GRCm38388,716,842 - 88,731,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,716,838 - 88,731,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv37388,520,776 - 88,534,970 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,802,791 - 88,815,654 (+)NCBIMGSCv36mm8
Celera388,758,569 - 88,772,478 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.95NCBI
Rit1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,478,616 - 176,493,269 (+)NCBIGRCr8
mRatBN7.22174,180,742 - 174,195,455 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,180,848 - 174,195,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2181,327,175 - 181,341,949 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02179,349,534 - 179,364,308 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02173,949,437 - 173,964,131 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02188,087,486 - 188,099,444 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,087,486 - 188,099,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,487,476 - 207,498,920 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,846,683 - 180,859,135 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2168,125,309 - 168,137,930 (+)NCBICelera
Cytogenetic Map2q34NCBI
Rit1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,089,536 - 2,099,404 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,089,530 - 2,099,404 (-)NCBIChiLan1.0ChiLan1.0
RIT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,894,726 - 41,903,450 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,895,330 - 41,901,173 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,384,004 - 41,392,704 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,761,662 - 41,770,357 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,762,237 - 41,770,224 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,542,190 - 41,550,885 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,595,838 - 41,604,533 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,880,003 - 41,888,698 (+)NCBIUU_Cfam_GSD_1.0
Rit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,126,969 - 26,136,903 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365805,156,565 - 5,167,040 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365805,157,351 - 5,166,790 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,117,882 - 94,127,384 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,117,721 - 94,127,882 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,860,735 - 102,869,029 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RIT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,965,944 - 7,979,396 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,966,057 - 7,976,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660387,270,415 - 7,284,182 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rit1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248851,275,765 - 1,284,613 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000063699   ⟹   ENSPPAP00000040780
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1135,063,000 - 135,074,942 (-)Ensembl
RefSeq Acc Id: XM_003821089   ⟹   XP_003821137
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2193,944,003 - 93,973,237 (+)NCBI
NHGRI_mPanPan1193,675,425 - 93,704,667 (+)NCBI
Mhudiblu_PPA_v01131,232,277 - 131,244,702 (-)NCBI
PanPan1.11135,062,994 - 135,074,941 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055100493   ⟹   XP_054956468
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2193,943,872 - 93,973,237 (+)NCBI
NHGRI_mPanPan1193,674,831 - 93,704,667 (+)NCBI
RefSeq Acc Id: XM_055100497   ⟹   XP_054956472
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2193,943,919 - 93,973,237 (+)NCBI
NHGRI_mPanPan1193,675,330 - 93,704,667 (+)NCBI
RefSeq Acc Id: XM_055100506   ⟹   XP_054956481
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2193,943,917 - 93,973,237 (+)NCBI
NHGRI_mPanPan1193,675,330 - 93,704,667 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003821137 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956468 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956472 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956481 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040780
  ENSPPAP00000040780.1
RefSeq Acc Id: XP_003821137   ⟸   XM_003821089
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CFQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000040780   ⟸   ENSPPAT00000063699
RefSeq Acc Id: XP_054956468   ⟸   XM_055100493
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054956472   ⟸   XM_055100497
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054956481   ⟸   XM_055100506
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043026 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063699.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
KEGG Report pps:100986791 UniProtKB/TrEMBL
NCBI Gene RIT1 ENTREZGENE
PANTHER GTP-BINDING PROTEIN RIT1 UniProtKB/TrEMBL
  PTHR24070 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9CFQ9 ENTREZGENE, UniProtKB/TrEMBL