TPPP2 (tubulin polymerization promoting protein family member 2) - Rat Genome Database

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Gene: TPPP2 (tubulin polymerization promoting protein family member 2) Pan paniscus
Analyze
Symbol: TPPP2
Name: tubulin polymerization promoting protein family member 2
RGD ID: 11803844
Description: ENCODES a protein that exhibits tubulin binding (inferred); INVOLVED IN microtubule bundle formation (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); purine nucleoside phosphorylase deficiency (ortholog); FOUND IN cytosol (inferred); microtubule (inferred); sperm flagellum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubulin polymerization-promoting protein family member 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,481,667 - 22,484,381 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,698,154 - 21,700,221 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,839,314 - 1,847,789 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,921,223 - 19,929,695 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,927,478 - 19,928,973 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TPPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,481,667 - 22,484,381 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,698,154 - 21,700,221 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,839,314 - 1,847,789 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,921,223 - 19,929,695 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,927,478 - 19,928,973 (+)Ensemblpanpan1.1panPan2
TPPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381421,024,299 - 21,036,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1421,024,109 - 21,036,276 (+)EnsemblGRCh38hg38GRCh38
GRCh371421,498,376 - 21,500,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,568,296 - 20,570,167 (+)NCBINCBI36Build 36hg18NCBI36
Build 341420,568,511 - 20,570,166NCBI
Celera141,359,208 - 1,361,197 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,619,284 - 1,621,273 (+)NCBIHuRef
CHM1_11421,500,454 - 21,502,443 (+)NCBICHM1_1
T2T-CHM13v2.01415,221,665 - 15,233,755 (+)NCBIT2T-CHM13v2.0
Tppp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391452,155,887 - 52,158,161 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1452,155,882 - 52,158,157 (+)EnsemblGRCm39 Ensembl
GRCm381451,918,430 - 51,920,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,918,425 - 51,920,700 (+)EnsemblGRCm38mm10GRCm38
MGSCv371452,538,436 - 52,540,375 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361450,840,376 - 50,842,651 (+)NCBIMGSCv36mm8
Celera1448,904,044 - 48,905,975 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1426.72NCBI
Tppp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81527,087,457 - 27,090,869 (+)NCBIGRCr8
mRatBN7.21524,614,284 - 24,627,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,614,006 - 24,618,967 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,385,402 - 27,387,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,341,123 - 28,343,417 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,594,067 - 26,596,361 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,319,175 - 28,321,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,319,136 - 28,321,476 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01532,131,751 - 32,134,449 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,351,907 - 27,354,201 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1524,919,795 - 24,922,089 (+)NCBICelera
Cytogenetic Map15p14NCBI
Tppp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,779,375 - 1,785,575 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,779,405 - 1,785,385 (+)NCBIChiLan1.0ChiLan1.0
TPPP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,118,516 - 18,126,661 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,119,594 - 18,126,663 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,603,958 - 18,612,111 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,379,272 - 18,387,432 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,380,689 - 18,382,319 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11518,060,621 - 18,068,781 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,116,582 - 18,124,736 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,244,499 - 18,252,668 (+)NCBIUU_Cfam_GSD_1.0
Tppp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,320,929 - 32,323,163 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936880230,626 - 232,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936880230,626 - 232,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,105,215 - 78,110,405 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,106,126 - 78,108,570 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TPPP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,503,616 - 21,505,890 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,504,299 - 21,505,799 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605924,929,967 - 24,932,053 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tppp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,021,639 - 7,023,027 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,021,146 - 7,023,129 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057563   ⟹   ENSPPAP00000034680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1419,927,478 - 19,928,973 (+)Ensembl
RefSeq Acc Id: XM_003804736   ⟹   XP_003804784
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21522,481,667 - 22,484,381 (+)NCBI
NHGRI_mPanPan11421,698,154 - 21,700,221 (+)NCBI
Mhudiblu_PPA_v0141,845,096 - 1,847,158 (+)NCBI
PanPan1.11419,927,082 - 19,929,071 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003804784 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034680.1
Reference Protein Sequences
RefSeq Acc Id: XP_003804784   ⟸   XM_003804736
- UniProtKB: A0A2R9C1M8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000034680   ⟸   ENSPPAT00000057563


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040174 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057563.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  P25-alpha UniProtKB/TrEMBL
NCBI Gene TPPP2 ENTREZGENE
PANTHER PTHR12932 UniProtKB/TrEMBL
  PTHR12932:SF21 UniProtKB/TrEMBL
Pfam p25-alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A2R9C1M8 ENTREZGENE, UniProtKB/TrEMBL