SCGN (secretagogin, EF-hand calcium binding protein)

Gene: SCGN (secretagogin, EF-hand calcium binding protein) Pan paniscus

Analyze

Symbol:

SCGN

Name:

secretagogin, EF-hand calcium binding protein

RGD ID:

11797055

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN regulation of long-term synaptic potentiation (inferred); regulation of presynaptic cytosolic calcium ion concentration (inferred); FOUND IN cytosol (inferred); dendrite (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

secretagogin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	40,299,097 - 40,367,239 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	36,300,454 - 36,350,030 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	25,486,599 - 25,571,272 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	25,812,650 - 25,862,236 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	25,812,443 - 25,862,227 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of long-term synaptic potentiation (IEA)

regulation of presynaptic cytosolic calcium ion concentration (IEA)

Cellular Component

cytosol (IEA)

dendrite (IEA)

nucleus (IEA)

synapse (IEA)

terminal bouton (IEA)

transport vesicle membrane (IEA)

Molecular Function

calcium ion binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SCGN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	40,299,097 - 40,367,239 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	36,300,454 - 36,350,030 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	25,486,599 - 25,571,272 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	25,812,650 - 25,862,236 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	25,812,443 - 25,862,227 (+)	Ensembl	panpan1.1		panPan2

SCGN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	25,652,215 - 25,701,783 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	25,652,201 - 25,701,783 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	25,652,443 - 25,702,011 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	25,760,408 - 25,809,990 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	25,760,407 - 25,809,985	NCBI
Celera	6	26,879,633 - 26,929,216 (+)	NCBI		Celera
Cytogenetic Map	6	p22.2	NCBI
HuRef	6	25,595,416 - 25,644,987 (+)	NCBI		HuRef
CHM1_1	6	25,654,627 - 25,704,213 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	25,518,025 - 25,567,550 (+)	NCBI		T2T-CHM13v2.0

Scgn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	24,137,439 - 24,175,310 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	24,137,439 - 24,175,197 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	23,953,456 - 23,991,327 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	23,953,456 - 23,991,214 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	24,045,325 - 24,083,083 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	23,960,921 - 23,998,679 (-)	NCBI		MGSCv36	mm8
Celera	13	24,185,142 - 24,222,913 (-)	NCBI		Celera
Cytogenetic Map	13	A3.1	NCBI
cM Map	13	10.01	NCBI

Scgn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	41,534,558 - 41,576,525 (+)	NCBI		GRCr8
mRatBN7.2	17	41,106,681 - 41,148,656 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	41,106,467 - 41,148,667 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	41,174,261 - 41,215,631 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	42,778,305 - 42,819,675 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	41,062,609 - 41,103,976 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	43,357,888 - 43,399,321 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	43,357,888 - 43,399,321 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	45,214,579 - 45,256,809 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	48,225,075 - 48,266,508 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	48,227,915 - 48,269,349 (+)	NCBI
Celera	17	40,739,598 - 40,779,916 (+)	NCBI		Celera
Cytogenetic Map	17	p11	NCBI

Scgn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955483	1,392,770 - 1,429,594 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955483	1,392,772 - 1,429,563 (-)	NCBI	ChiLan1.0	ChiLan1.0

SCGN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	23,602,244 - 23,638,108 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	23,602,343 - 23,638,055 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	23,531,684 - 23,540,559 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	23,717,908 - 23,753,767 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	23,717,868 - 23,753,765 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	23,527,247 - 23,563,304 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	23,577,972 - 23,614,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	25,015,623 - 25,051,501 (+)	NCBI		UU_Cfam_GSD_1.0

Scgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	1,929,640 - 1,965,364 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936671	1,655,978 - 1,693,175 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936671	1,656,179 - 1,696,580 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCGN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	20,389,493 - 20,432,978 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	20,389,156 - 20,432,985 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	21,689,440 - 21,732,931 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCGN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	46,554,759 - 46,605,282 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	46,565,302 - 46,604,710 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	25,585,367 - 25,635,700 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Scgn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624756	1,368,434 - 1,407,885 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624756	1,368,330 - 1,407,914 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003823211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063605180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004671867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004671868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000041780 ⟹ ENSPPAP00000019031

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	6	25,812,443 - 25,862,227 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000041783 ⟹ ENSPPAP00000019034

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	6	25,821,878 - 25,861,787 (+)	Ensembl

RefSeq Acc Id:

XM_003823211 ⟹ XP_003823259

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	5	40,299,097 - 40,348,665 (+)	NCBI
NHGRI_mPanPan1	6	36,300,454 - 36,350,030 (+)	NCBI
Mhudiblu_PPA_v0	6	25,486,599 - 25,536,237 (+)	NCBI
PanPan1.1	6	25,812,650 - 25,862,236 (+)	NCBI

Sequence:

show sequence

AGGACAGCGCGCAGGGCGGGGCGGGGACAGGCGCGCCAGGAGCGGGGCGGGCTTCCAGCCGCTG
GTTTTGCTGAGGGCTGAGGGACGGCTCAGCGACGCCACGGCCAGCAGCGCTCGCGTCCTCCCCA
GCAACAGTTACTCAAAGCTAATCAGATAGCGAAAGAAGCAGGAGAGCGAGTCAAGAAATACGGT
GAAGGAGTCCTTCCCAAAGTTGTCTAGGTCCTTCCGCGCCGGTGCCTGGTCTTCATCGTCAACA
CCATGGACAGCTCCCGGGAACCGACTCCGGGGCGCTTGGACGCCGCTGGCTTCTGGCAGGTCTG
GCAGCGCTTTGATGCGGATGAAAAAGGTTACATAGAAGAGAAGGAACTCGATGCTTTCTTTCTC
CACATGTTGATGAAACTGGGTACTGATGACACGGTCATGAAAGCAAATTTGCACAAGGTGAAAC
AGCAATTTATGACTACCCAAGATGCCTCTAAAGATGGTCGCATTCGGATGAAAGAGCTTGCTGG
TATGTTCTTATCTGAGGATGAAAACTTTCTTCTGCTCTTTCGCCGGGAAAACCCACTGGACAGC
AGCGTGGAGTTTATGCAGATTTGGCGCAAATATGACGCTGACAGCAGTGGCTTTATATCAGCTG
CTGAGCTCCGCAACTTCCTCCGAGACCTCTTTCTTCACCACAAAAAGGCCATTTCTGAGGCTAA
ACTGGAAGAATACACTGGCACCATGATGAAGATTTTTGACAGAAATAAAGATGGTCGGTTGGAT
CTAAATGACTTAGCAAGGATTCTGGCTCTTCAGGAAAACTTCCTTCTCCAATTTAAAATGGATG
CTTGTTCTACTGAAGAAAGGAAAAGGGACTTTGAGAAAATCTTTGCCTACTATGATGTTAGTAA
AACAGGAGCCCTGGAAGGCCCAGAAGTGGATGGGTTTGTCAAAGACATGATGGAGCTTGTCCAG
CCCAGCATCAGCGGGGTGGACCTTGATAAGTTCCGCGAGATTCTCTTGCGTCACTGCGACGTGA
ACAAGGATGGAAAAATTCAGAAGTCTGAGCTGGCTTTGTGTCTTGGGCTGAAAATCAACCCATA
ATCCCAGACTGCTTTGCCTTTTGCTCTTACTATGTTTCTGTGATCTTGCTGATAGAATTGTATC
TGTGCATTGATGTTGGGGACACAGTGGGCAAACTCACAAATGGTGTGCTATTCTTGGGCAAGAA
GAGGGACGCTAGGGCCTTCCTTCCACCGGCGTGATCTATCCCTGTCTCACTGAAAGCCCCTGTG
TAGTGTCTGTGTTGTTTTCCCTTGACCCTGGGCTTTCCTATCCTCCCAAAGACTCAGCTCCCCT
GTTAGATGGCTCTGCCTGTCCTTCCCCAGTCACCAGGGTGGGGGGGACAGGGGCAGCTGAGTGC
ATTCATTTTGTGCTTTTCTTGTGGGCTTTCTGCTTAGTCTGAAAGGTGTGTGGCATTCATGGCA
ATCCTGTAACTTCAACATAGATTTTTTTTGTGTGTGTGGAAATAAATCTGCAATTGGAAACAAA
AA

hide sequence

RefSeq Acc Id:

XM_063605180 ⟹ XP_063461250

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	5	40,299,115 - 40,367,239 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003823259	(Get FASTA)	NCBI Sequence Viewer
	XP_063461250	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000019031
	ENSPPAP00000019031.1
	ENSPPAP00000019034.1

RefSeq Acc Id:	XP_003823259 ⟸ XM_003823211
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9ANV7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDSSREPTPGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLHKVKQ QFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDADSSGFISAA ELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILALQENFLLQFKMDA CSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVN KDGKIQKSELALCLGLKINP hide sequence

RefSeq Acc Id:

ENSPPAP00000019034 ⟸ ENSPPAT00000041783

RefSeq Acc Id:

ENSPPAP00000019031 ⟸ ENSPPAT00000041780

RefSeq Acc Id:	XP_063461250 ⟸ XM_063605180
- Peptide Label:	isoform X2

Protein Domains

EF-hand

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000032691	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000041780.1	UniProtKB/TrEMBL
	ENSPPAT00000041783.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	EFh_SCGN	UniProtKB/TrEMBL
KEGG Report	pps:100978622	UniProtKB/TrEMBL
NCBI Gene	SCGN	ENTREZGENE
PANTHER	CALBINDIN	UniProtKB/TrEMBL
	SECRETAGOGIN	UniProtKB/TrEMBL
Pfam	EF-hand_5	UniProtKB/TrEMBL
	EF-hand_7	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A2R9ANV7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AVP9_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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