FRMD4B (FERM domain containing 4B) - Rat Genome Database

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Gene: FRMD4B (FERM domain containing 4B) Pan paniscus
Analyze
Symbol: FRMD4B
Name: FERM domain containing 4B
RGD ID: 11792462
Description: ENCODES a protein that exhibits cytoskeletal protein binding (inferred); INVOLVED IN establishment of epithelial cell polarity (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); genetic disease (ortholog); FOUND IN adherens junction (inferred); bicellular tight junction (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FERM domain-containing protein 4B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2269,124,610 - 69,497,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1369,130,439 - 69,502,383 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0369,105,231 - 69,478,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1370,471,897 - 70,842,474 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,471,897 - 70,686,895 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FRMD4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2269,124,610 - 69,497,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1369,130,439 - 69,502,383 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0369,105,231 - 69,478,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1370,471,897 - 70,842,474 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,471,897 - 70,686,895 (-)Ensemblpanpan1.1panPan2
FRMD4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38369,168,782 - 69,542,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl369,168,782 - 69,542,583 (-)EnsemblGRCh38hg38GRCh38
GRCh37369,217,933 - 69,435,239 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,301,836 - 69,518,120 (-)NCBINCBI36Build 36hg18NCBI36
Build 34369,302,666 - 69,332,399NCBI
Celera369,147,274 - 69,362,951 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef369,220,047 - 69,435,240 (-)NCBIHuRef
CHM1_1369,170,368 - 69,386,663 (-)NCBICHM1_1
T2T-CHM13v2.0369,205,753 - 69,579,785 (-)NCBIT2T-CHM13v2.0
Frmd4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,263,828 - 97,594,618 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl697,263,828 - 97,594,502 (-)EnsemblGRCm39 Ensembl
GRCm38697,286,867 - 97,617,657 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,286,867 - 97,617,541 (-)EnsemblGRCm38mm10GRCm38
MGSCv37697,236,861 - 97,567,651 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36697,252,330 - 97,583,044 (-)NCBIMGSCv36mm8
Celera699,148,219 - 99,479,337 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map644.93NCBI
Frmd4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84131,452,361 - 131,778,734 (-)NCBIGRCr8
mRatBN7.24129,895,401 - 130,222,070 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4129,895,708 - 130,084,197 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04129,658,137 - 129,984,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,658,840 - 129,846,642 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,157,499 - 194,480,974 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44132,012,943 - 132,207,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14132,278,240 - 132,323,694 (-)NCBI
Celera4118,771,260 - 119,095,704 (-)NCBICelera
Cytogenetic Map4q34NCBI
Frmd4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542118,483,857 - 18,673,519 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542118,423,238 - 18,669,514 (+)NCBIChiLan1.0ChiLan1.0
FRMD4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12022,253,619 - 22,574,917 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2022,402,128 - 22,598,594 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2022,222,606 - 22,544,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02022,282,339 - 22,600,372 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2022,430,099 - 22,600,861 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12021,968,263 - 22,290,330 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02022,317,068 - 22,639,260 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02022,387,643 - 22,710,010 (+)NCBIUU_Cfam_GSD_1.0
Frmd4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,349,427 - 1,485,645 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366031,369,851 - 1,485,661 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366031,369,943 - 1,485,645 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMD4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,597,414 - 50,980,016 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,602,910 - 50,980,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,735,642 - 56,114,900 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMD4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,196,103 - 30,554,140 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2230,195,908 - 30,452,885 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041136,232,993 - 136,595,817 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmd4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247733,763,222 - 3,961,536 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247733,763,706 - 3,961,465 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000023282   ⟹   ENSPPAP00000005093
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl370,471,897 - 70,686,895 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000023293   ⟹   ENSPPAP00000005095
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl370,473,762 - 70,686,586 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000023297   ⟹   ENSPPAP00000005096
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl370,473,762 - 70,686,586 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000023311   ⟹   ENSPPAP00000005102
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl370,473,767 - 70,686,586 (-)Ensembl
RefSeq Acc Id: XM_003811580   ⟹   XP_003811628
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2269,124,610 - 69,341,564 (-)NCBI
NHGRI_mPanPan1369,130,439 - 69,346,342 (-)NCBI
Mhudiblu_PPA_v0369,105,231 - 69,322,159 (-)NCBI
PanPan1.1370,471,897 - 70,686,895 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008963959   ⟹   XP_008962207
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2269,124,610 - 69,497,596 (-)NCBI
NHGRI_mPanPan1369,130,439 - 69,502,383 (-)NCBI
Mhudiblu_PPA_v0369,106,002 - 69,478,192 (-)NCBI
PanPan1.1370,472,167 - 70,842,474 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034956862   ⟹   XP_034812753
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2269,124,610 - 69,309,013 (-)NCBI
NHGRI_mPanPan1369,130,439 - 69,313,787 (-)NCBI
Mhudiblu_PPA_v0369,106,002 - 69,289,533 (-)NCBI
RefSeq Acc Id: XM_034956863   ⟹   XP_034812754
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2269,124,610 - 69,393,379 (-)NCBI
NHGRI_mPanPan1369,130,439 - 69,398,171 (-)NCBI
Mhudiblu_PPA_v0369,106,002 - 69,373,998 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003811628   ⟸   XM_003811580
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZJC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008962207   ⟸   XM_008963959
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034812754   ⟸   XM_034956863
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034812753   ⟸   XM_034956862
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000005095   ⟸   ENSPPAT00000023293
RefSeq Acc Id: ENSPPAP00000005096   ⟸   ENSPPAT00000023297
RefSeq Acc Id: ENSPPAP00000005093   ⟸   ENSPPAT00000023282
RefSeq Acc Id: ENSPPAP00000005102   ⟸   ENSPPAT00000023311
Protein Domains
FERM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000021170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000023282.1 UniProtKB/TrEMBL
  ENSPPAT00000023293.1 UniProtKB/TrEMBL
  ENSPPAT00000023297.1 UniProtKB/TrEMBL
  ENSPPAT00000023311.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  DUF3338 UniProtKB/TrEMBL
  Ez/rad/moesin-like UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_CS UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  FERM_PH-like_C UniProtKB/TrEMBL
  FRMD4A/B UniProtKB/TrEMBL
  FRMD4A/B_FERM_C UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report pps:100968771 UniProtKB/TrEMBL
NCBI Gene FRMD4B ENTREZGENE
PANTHER FERM DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  FERM DOMAIN-CONTAINING PROTEIN 4B UniProtKB/TrEMBL
Pfam CUPID UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
PRINTS BAND41 UniProtKB/TrEMBL
  ERMFAMILY UniProtKB/TrEMBL
PROSITE FERM_2 UniProtKB/TrEMBL
  FERM_3 UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A2R8ZJC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZJG5_PANPA UniProtKB/TrEMBL
  A0A2R8ZMC5_PANPA UniProtKB/TrEMBL
  A0A2R8ZQJ3_PANPA UniProtKB/TrEMBL