ARHGAP1 (Rho GTPase activating protein 1)

Gene: ARHGAP1 (Rho GTPase activating protein 1) Pan paniscus

Analyze

Symbol:

ARHGAP1

Name:

Rho GTPase activating protein 1

RGD ID:

11789730

Description:

ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (ortholog); ASSOCIATED WITH congenital disorder of glycosylation type IIc (ortholog); intellectual disability (ortholog); Premature Aging (ortholog); FOUND IN cell leading edge (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

rho GTPase-activating protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	48,880,858 - 48,905,978 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	48,900,620 - 48,925,755 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	46,626,174 - 46,651,308 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	47,185,415 - 47,209,813 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	47,185,415 - 47,209,765 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation type IIc (ISO)

intellectual disability (ISO)

Premature Aging (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endosomal transport (IEA)

negative regulation of endocytic recycling (IEA)

signal transduction (IEA)

small GTPase-mediated signal transduction (IEA,ISO)

transferrin transport (IEA)

Cellular Component

cell leading edge (ISO)

cytoplasm (IEA)

endosome membrane (IEA)

membrane (IEA)

perinuclear region of cytoplasm (IEA,ISO)

plasma membrane (ISO)

ruffle (ISO)

sorting endosome (IEA)

Molecular Function

GTPase activator activity (IEA)

protein binding (ISO)

small GTPase binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

ARHGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	48,880,858 - 48,905,978 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	48,900,620 - 48,925,755 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	46,626,174 - 46,651,308 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	47,185,415 - 47,209,813 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	47,185,415 - 47,209,765 (-)	Ensembl	panpan1.1		panPan2

ARHGAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	46,677,080 - 46,700,619 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	46,677,080 - 46,700,619 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	46,698,630 - 46,722,169 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	46,655,206 - 46,678,696 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	46,655,209 - 46,678,696	NCBI
Celera	11	46,846,844 - 46,870,551 (-)	NCBI		Celera
Cytogenetic Map	11	p11.2	NCBI
HuRef	11	46,404,665 - 46,428,254 (-)	NCBI		HuRef
CHM1_1	11	46,697,036 - 46,720,625 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	46,833,096 - 46,856,635 (-)	NCBI		T2T-CHM13v2.0

Arhgap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	91,480,463 - 91,502,670 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	91,480,205 - 91,502,671 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	91,650,118 - 91,672,325 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	91,649,860 - 91,672,326 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	91,490,275 - 91,512,482 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	91,454,047 - 91,473,157 (+)	NCBI		MGSCv36	mm8
Celera	2	93,039,665 - 93,061,789 (+)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI
cM Map	2	50.63	NCBI

Arhgap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	98,077,064 - 98,099,163 (+)	NCBI		GRCr8
mRatBN7.2	3	77,621,377 - 77,643,400 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	77,620,655 - 77,643,396 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	81,096,877 - 81,118,411 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	89,695,902 - 89,717,436 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	87,547,185 - 87,568,702 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	80,555,196 - 80,576,881 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	80,555,196 - 80,576,856 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	87,254,371 - 87,275,981 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	76,030,806 - 76,052,736 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	75,931,036 - 75,947,686 (+)	NCBI
Celera	3	76,826,841 - 76,847,615 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

Arhgap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	1,378,426 - 1,396,899 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	1,378,426 - 1,395,439 (+)	NCBI	ChiLan1.0	ChiLan1.0

ARHGAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	42,813,580 - 42,832,054 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	42,813,693 - 42,830,458 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	41,545,991 - 41,559,181 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	43,469,679 - 43,488,158 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	43,469,753 - 43,488,150 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	42,958,392 - 42,971,585 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	42,514,027 - 42,527,216 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	43,243,313 - 43,256,512 (+)	NCBI		UU_Cfam_GSD_1.0

Arhgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	20,289,302 - 20,308,993 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936562	2,400,422 - 2,420,766 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936562	2,400,983 - 2,420,635 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARHGAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	15,834,703 - 15,854,179 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	15,834,285 - 15,854,181 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	17,185,458 - 17,205,207 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARHGAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	18,627,534 - 18,648,984 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	18,627,611 - 18,650,706 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	115,911,102 - 115,933,286 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arhgap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	1,905,283 - 1,922,263 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	1,905,217 - 1,922,263 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003815207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008968129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008968130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063608430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000032083 ⟹ ENSPPAP00000009440

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	47,185,415 - 47,206,461 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000032090 ⟹ ENSPPAP00000009447

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	47,187,371 - 47,209,765 (-)	Ensembl

RefSeq Acc Id:

XM_003815207 ⟹ XP_003815255

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	48,880,858 - 48,905,978 (-)	NCBI
NHGRI_mPanPan1	11	48,900,620 - 48,925,755 (-)	NCBI
Mhudiblu_PPA_v0	11	46,626,174 - 46,651,308 (-)	NCBI
PanPan1.1	11	47,185,415 - 47,209,813 (-)	NCBI

Sequence:

show sequence

AATGGTTGGGGATAGAAGAGAGCGGGAGGGGGCGGTTCCCGTTCCACCTCGGAGCCGGATGTTT
GCCGAGCCTTGACAGGCGTGGCAGAGGGAGCAGTGCCCGAGCGCGGTTTCTCTTAAGGTTCTGC
AGGGCAAGGCTGTCTGGGACAGGCTTGGCCATGGATCCGCTCTCAGAGCTGCAGGATGATCTGA
CCTTGGATGACACCAGCGAGGCTCTGAACCAGCTGAAGCTGGCCTCCATCGATGAGAAGAACTG
GCCCTCGGATGAAATGCCTGAGTTCCCCAAGTCAGATGACTCCAAAAGCAGCTCCCCGGAACTT
GTCACACACCTGAAGTGGGATGACCCATACTATGACATCGCCCGGCACCAGATCGTGGAGGTGG
CAGGAGATGACAAGTATGGGCGGAAGATCATTGTGTTTAGTGCCTGTCGAATGCCCCCCAGCCA
CCAGCTCGACCACAGCAAGCTCCTGGGGTACCTGAAGCACACCCTGGACCAGTACGTGGAGAGT
GACTACACACTTCTGTATCTGCACCACGGCCTGACCAGCGACAACAAGCCCTCCCTCAGCTGGC
TCCGTGATGCCTACCGGGAGTTTGACCGCAAGTACAAGAAGAACATCAAGGCCTTGTACATCGT
GCATCCGACCATGTTCATCAAAACTCTGCTCATCCTCTTCAAGCCCCTCATCAGCTTCAAGTTC
GGGCAGAAGATCTTCTATGTGAATTACCTGAGCGAGCTGAGCGAGCACGTGAAGCTGGAGCAGC
TGGGGATCCCTCGCCAAGTGCTCAAATATGACGACTTCCTGAAATCCACACAGAAGAGCCCCGC
GACAGCCCCCAAGCCCATGCCCCCACGGCCCCCCCTGCCCAACCAGCAGTTTGGAGTCTCGCTG
CAGCACCTCCAGGAGAAGAATCCAGAGCAGGAGCCCATTCCCATTGTACTCAGGGAGACTGTTG
CCTACTTACAGGCCCACGCTCTCACCACCGAGGGCATCTTCCGGAGGTCGGCCAACACCCAAGT
GGTCCGGGAAGTACAGCAGAAGTACAACATGGGGCTGCCTGTGGATTTCGACCAGTACAATGAG
CTGCACCTGCCAGCAGTCATCCTCAAGACCTTCCTCCGGGAGCTTCCTGAGCCCCTGCTCACCT
TTGACCTCTACCCCCATGTGGTGGGCTTCCTCAACATTGATGAAAGCCAGAGGGTGCCAGTGAC
ACTGCAGGTCCTCCAGACGCTGCCCGAGGAGAACTACCAGGTGCTTCGTTTCCTGACTGCTTTC
CTGGTGCAGATTTCTGCACACAGTGACCAGAACAAGATGACCAACACTAACCTGGCTGTTGTTT
TCGGCCCTAACCTGCTGTGGGCCAAGGATGCGGCCATCACCCTCAAGGCCATTAATCCCATCAA
CACCTTCACCAAGTTCCTTCTGGATCACCAAGGGGAGGTGTTCCGAAGCCCGGACCCCAGCGGG
CTCTGAACCTGGCCCCTGCCCCACCAGCCCCTTCTCTGGTAGCCCGGGTTTGGACTCTTCCTCC
TGGCATCAGGGGCCATGAAGCCCCCTGGAGAGAGATGTTGGAGCCACCCATCAGGCATGCTCTC
CCCCACCTCTGTCCAGCCCGCCTCACGGCCCTGGCAGCCTCGCTGTTACCAGAAGACGTTTTTC
TCTGCCTTACACTTCTCACTGCCTCTCTGGACACCTGGCTTTTGCTGGGCTCTCCAGAGCTGGG
CTTGGCTCTTCCAGCTGGAGAAGGACTGAGCCCCAGTAACCCCTTTCCTGCATTTTCCTGCCTC
TGTTTCCCTAGCAAGTGTGGATGAATCAAATGACTGCCGGCTGGGCTGGTAGCAGGGGCCAGTC
CTCCCCTCTTGATTGCTGGGAATGAGCAGCTGAGCTCTTTGGTGTGGACACCGCCCCAAGCTGA
GGTGCCTCCCTATCTGGTAGGCTGCCCTGCTTTGCAGAAGCCCCACTGCATGAAGGCTTGAGTG
CAAGCACCCTTGCTCCTGTACTGCCCCCAGCAGCGCAGTCTGGGGTATTTCCCCTGCTGAGGAG
TGACAGGGCTGGAGCCTGTGTCTGCTTTCTGCCTCCTCTTCCACACATCCTGGGTCAGCCTTTC
CCAAGTGATACTGCCCCTGGGGTGTCCTAACCCCTTGGTTGTGCAGGGACTGGTAGCTTGGATG
ACACGGCTCAGAGTCCCAGCATCCACTTGAAACCTCCCTCTCCACCTCCCCGCCCCCGAGAGCT
ACAGTGTGCGATGGAATCAGTGACCGGCCAGGTTAGCCTCTCCCCTCTTGGCCTCCTTTCCCAC
ACGGGCAGATCATCAGCCTTCATGTTCTTGTGGACCTGTCTGTTATGGAGTCACACTGGCCCCT
GCCCCGGCCAGAGGTGACTCAGTGCCTCAGGATCTGTGTGGCTCCTTCCTCCAGCTGGGGGACT
CTTAAAGGGGCTGGGGTAGAGACTAAGAGTGCCTGTAGGAGGGGCAGAGATTGTGCTGATAGGT
CAGTCCAGATAGGTGGGTTCTAGCAATTTCCCCAGGGGATTAAGGGGCTCTAGGGCCACTTTTT
TTTTTTTTCTTGAGATGGAGTCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGC
ACACCTCCGCCTTCTGAGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGGAGCTGGGACTATA
GGTGCATGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTG
GCCAGGATGGTCTCGATCTCCTGACCTCATGATCCATCCACCTCGGCCTCCCAAAGTGCTGGGA
TTCCAGGCGTGAGCCACCGCGCCCGGCCAGCTCTGTTGTCTTTCAAAGAACCTCGGCCCCAGTG
ATGGCTGATCTCACTCCCACTGTCTCGTAGAATTACACTCCTTCCTGGGGATCCCTCTTCCTGC
AGCCTTGTCCTTGGGGAGTACAGGGAAGTACCTGCAGTGACCCTGCCCCCATGACCTTGGCCAG
GCAGGATGATTCCAGAGCCCATACTGTGGGGATCCTCACTGACCAGCCCAGCCCCATCCGCAAG
CCAGGCTGGGCCTGGGCATAACTTCGCTGGGCTCTCCCAAGACCATCAGCAGTGCATCCAGCCC
CCTGGGGCCTGGGCTGCTGCTGGTTCTTCATCAGTCCCTTGGTCTCTAGCCTCAGCCAGGGCTG
CTCTGCTCTCCGCCCTCCTTTGTGTATCAAGTGTCGCTCACAGCCCCATTCACTGGGGAGCCTT
TCGGATCTATTTGGTCTTTCTCATGTCCCCCACTGGTCTGTACCCCAGGGAGCGGGTGCTTGTA
CTGTGAATCCAGTGTTCACATTCACACTTAATGACTTCTTGGCACCAATCATGTATTTCACCGT
TTGCACTTTTTGTATTTCAATAAAAATGGAGATGCAAAACTG

hide sequence

RefSeq Acc Id:

XM_008968130 ⟹ XP_008966378

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	48,880,858 - 48,905,978 (-)	NCBI
NHGRI_mPanPan1	11	48,900,620 - 48,925,755 (-)	NCBI
Mhudiblu_PPA_v0	11	46,626,940 - 46,651,308 (-)	NCBI
PanPan1.1	11	47,185,415 - 47,209,813 (-)	NCBI

Sequence:

show sequence

AATGGTTGGGGATAGAAGAGAGCGGGAGGGGGCGGTTCCCGTTCCACCTCGGAGCCGGATGTTT
GCCGAGCCTTGACAGGCGTGGCAGAGGGAGCAGTGCCCGAGCGCGGTTTCTCTTAAGGTTCTGC
AGGGCAAGGCTGTCTGGGACAGGCTTGGCCATGGATCCGCTCTCAGAGCTGCAGGATGATCTGA
CCTTGGATGACACCAGCGAGGCTCTGAACCAGCTGAAGCTGGCCTCCATCGATGAGAAGAACTG
GCCCTCGGATGAAATGCCTGAGTTCCCCAAGTCAGATGACTCCAAAAGCAGCTCCCCGGAACTT
GTCACACACCTGAAGTGGGATGACCCATACTATGACATCGCCCGGCACCAGATCGTGGAGGTGG
CAGGAGATGACAAGTATGGGCGGAAGATCATTGTGTTTAGTGCCTGTCGAATGCCCCCCAGCCA
CCAGCTCGACCACAGCAAGCTCCTGGGGTACAAGAAGAACATCAAGGCCTTGTACATCGTGCAT
CCGACCATGTTCATCAAAACTCTGCTCATCCTCTTCAAGCCCCTCATCAGCTTCAAGTTCGGGC
AGAAGATCTTCTATGTGAATTACCTGAGCGAGCTGAGCGAGCACGTGAAGCTGGAGCAGCTGGG
GATCCCTCGCCAAGTGCTCAAATATGACGACTTCCTGAAATCCACACAGAAGAGCCCCGCGACA
GCCCCCAAGCCCATGCCCCCACGGCCCCCCCTGCCCAACCAGCAGTTTGGAGTCTCGCTGCAGC
ACCTCCAGGAGAAGAATCCAGAGCAGGAGCCCATTCCCATTGTACTCAGGGAGACTGTTGCCTA
CTTACAGGCCCACGCTCTCACCACCGAGGGCATCTTCCGGAGGTCGGCCAACACCCAAGTGGTC
CGGGAAGTACAGCAGAAGTACAACATGGGGCTGCCTGTGGATTTCGACCAGTACAATGAGCTGC
ACCTGCCAGCAGTCATCCTCAAGACCTTCCTCCGGGAGCTTCCTGAGCCCCTGCTCACCTTTGA
CCTCTACCCCCATGTGGTGGGCTTCCTCAACATTGATGAAAGCCAGAGGGTGCCAGTGACACTG
CAGGTCCTCCAGACGCTGCCCGAGGAGAACTACCAGGTGCTTCGTTTCCTGACTGCTTTCCTGG
TGCAGATTTCTGCACACAGTGACCAGAACAAGATGACCAACACTAACCTGGCTGTTGTTTTCGG
CCCTAACCTGCTGTGGGCCAAGGATGCGGCCATCACCCTCAAGGCCATTAATCCCATCAACACC
TTCACCAAGTTCCTTCTGGATCACCAAGGGGAGGTGTTCCGAAGCCCGGACCCCAGCGGGCTCT
GAACCTGGCCCCTGCCCCACCAGCCCCTTCTCTGGTAGCCCGGGTTTGGACTCTTCCTCCTGGC
ATCAGGGGCCATGAAGCCCCCTGGAGAGAGATGTTGGAGCCACCCATCAGGCATGCTCTCCCCC
ACCTCTGTCCAGCCCGCCTCACGGCCCTGGCAGCCTCGCTGTTACCAGAAGACGTTTTTCTCTG
CCTTACACTTCTCACTGCCTCTCTGGACACCTGGCTTTTGCTGGGCTCTCCAGAGCTGGGCTTG
GCTCTTCCAGCTGGAGAAGGACTGAGCCCCAGTAACCCCTTTCCTGCATTTTCCTGCCTCTGTT
TCCCTAGCAAGTGTGGATGAATCAAATGACTGCCGGCTGGGCTGGTAGCAGGGGCCAGTCCTCC
CCTCTTGATTGCTGGGAATGAGCAGCTGAGCTCTTTGGTGTGGACACCGCCCCAAGCTGAGGTG
CCTCCCTATCTGGTAGGCTGCCCTGCTTTGCAGAAGCCCCACTGCATGAAGGCTTGAGTGCAAG
CACCCTTGCTCCTGTACTGCCCCCAGCAGCGCAGTCTGGGGTATTTCCCCTGCTGAGGAGTGAC
AGGGCTGGAGCCTGTGTCTGCTTTCTGCCTCCTCTTCCACACATCCTGGGTCAGCCTTTCCCAA
GTGATACTGCCCCTGGGGTGTCCTAACCCCTTGGTTGTGCAGGGACTGGTAGCTTGGATGACAC
GGCTCAGAGTCCCAGCATCCACTTGAAACCTCCCTCTCCACCTCCCCGCCCCCGAGAGCTACAG
TGTGCGATGGAATCAGTGACCGGCCAGGTTAGCCTCTCCCCTCTTGGCCTCCTTTCCCACACGG
GCAGATCATCAGCCTTCATGTTCTTGTGGACCTGTCTGTTATGGAGTCACACTGGCCCCTGCCC
CGGCCAGAGGTGACTCAGTGCCTCAGGATCTGTGTGGCTCCTTCCTCCAGCTGGGGGACTCTTA
AAGGGGCTGGGGTAGAGACTAAGAGTGCCTGTAGGAGGGGCAGAGATTGTGCTGATAGGTCAGT
CCAGATAGGTGGGTTCTAGCAATTTCCCCAGGGGATTAAGGGGCTCTAGGGCCACTTTTTTTTT
TTTTCTTGAGATGGAGTCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGCGATCTCGGCACAC
CTCCGCCTTCTGAGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGGAGCTGGGACTATAGGTG
CATGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCA
GGATGGTCTCGATCTCCTGACCTCATGATCCATCCACCTCGGCCTCCCAAAGTGCTGGGATTCC
AGGCGTGAGCCACCGCGCCCGGCCAGCTCTGTTGTCTTTCAAAGAACCTCGGCCCCAGTGATGG
CTGATCTCACTCCCACTGTCTCGTAGAATTACACTCCTTCCTGGGGATCCCTCTTCCTGCAGCC
TTGTCCTTGGGGAGTACAGGGAAGTACCTGCAGTGACCCTGCCCCCATGACCTTGGCCAGGCAG
GATGATTCCAGAGCCCATACTGTGGGGATCCTCACTGACCAGCCCAGCCCCATCCGCAAGCCAG
GCTGGGCCTGGGCATAACTTCGCTGGGCTCTCCCAAGACCATCAGCAGTGCATCCAGCCCCCTG
GGGCCTGGGCTGCTGCTGGTTCTTCATCAGTCCCTTGGTCTCTAGCCTCAGCCAGGGCTGCTCT
GCTCTCCGCCCTCCTTTGTGTATCAAGTGTCGCTCACAGCCCCATTCACTGGGGAGCCTTTCGG
ATCTATTTGGTCTTTCTCATGTCCCCCACTGGTCTGTACCCCAGGGAGCGGGTGCTTGTACTGT
GAATCCAGTGTTCACATTCACACTTAATGACTTCTTGGCACCAATCATGTATTTCACCGTTTGC
ACTTTTTGTATTTCAATAAAAATGGAGATGCAAAACTG

hide sequence

RefSeq Acc Id:

XM_063608430 ⟹ XP_063464500

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	48,880,858 - 48,904,510 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003815255	(Get FASTA)	NCBI Sequence Viewer
	XP_008966378	(Get FASTA)	NCBI Sequence Viewer
	XP_063464500	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000009440.1
	ENSPPAP00000009447.1

RefSeq Acc Id:	XP_008966378 ⟸ XM_008968130
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZXZ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPEFPKSDDSKSSSPELVTHLKWDDPY YDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYKKNIKALYIVHPTMFIKTLLI LFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPP LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPVTLQVLQTLPEEN YQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQG EVFRSPDPSGL hide sequence

RefSeq Acc Id:	XP_003815255 ⟸ XM_003815207
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZXZ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPEFPKSDDSKSSSPELVTHLKWDDPY YDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHG LTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYL SELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQ EPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKT FLRELPEPLLTFDLYPHVVGFLNIDESQRVPVTLQVLQTLPEENYQVLRFLTAFLVQISAHSDQ NKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGEVFRSPDPSGL hide sequence

RefSeq Acc Id:

ENSPPAP00000009447 ⟸ ENSPPAT00000032090

RefSeq Acc Id:

ENSPPAP00000009440 ⟸ ENSPPAT00000032083

RefSeq Acc Id:	XP_063464500 ⟸ XM_063608430
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R8ZWT4 (UniProtKB/TrEMBL)

Protein Domains

CRAL-TRIO Rho-GAP

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000027953	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000032083.1	UniProtKB/TrEMBL
	ENSPPAT00000032090.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.555.10	UniProtKB/TrEMBL
	3.40.525.10	UniProtKB/TrEMBL
InterPro	ARHGAP1_RhoGAP	UniProtKB/TrEMBL
	CRAL-TRIO_dom	UniProtKB/TrEMBL
	CRAL-TRIO_dom_sf	UniProtKB/TrEMBL
	Rho_GTPase_activation_prot	UniProtKB/TrEMBL
	RhoGAP_dom	UniProtKB/TrEMBL
KEGG Report	pps:100977672	UniProtKB/TrEMBL
NCBI Gene	ARHGAP1	ENTREZGENE
PANTHER	RHO GTPASE-ACTIVATING PROTEIN 1	UniProtKB/TrEMBL
	RHO GTPASE-ACTIVATING PROTEIN 68F	UniProtKB/TrEMBL
Pfam	CRAL_TRIO_2	UniProtKB/TrEMBL
	RhoGAP	UniProtKB/TrEMBL
PROSITE	CRAL_TRIO	UniProtKB/TrEMBL
	RHOGAP	UniProtKB/TrEMBL
SMART	RhoGAP	UniProtKB/TrEMBL
	SEC14	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48350	UniProtKB/TrEMBL
	SSF52087	UniProtKB/TrEMBL
UniProt	A0A2R8ZWT4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZXZ2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar