SEL1L2 (SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SEL1L2 (SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase) Pan paniscus
Analyze
Symbol: SEL1L2
Name: SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase
RGD ID: 11780215
Description: INVOLVED IN ERAD pathway (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100989420; LOC112437990; protein sel-1 homolog 2-like; SEL1L2 adaptor subunit of ERAD E3 ligase; SEL1L2 adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L2 ERAD E3 ligase adaptor subunit; SEL1L2, ERAD E3 ligase adaptor subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22114,740,819 - 14,889,937 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12014,737,650 - 14,886,769 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02013,815,019 - 13,966,202 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12013,800,211 - 13,870,470 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2013,800,212 - 13,945,070 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
ERAD pathway  (IEA)

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SEL1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22114,740,819 - 14,889,937 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12014,737,650 - 14,886,769 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02013,815,019 - 13,966,202 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12013,800,211 - 13,870,470 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2013,800,212 - 13,945,070 (-)Ensemblpanpan1.1panPan2
SEL1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382013,849,247 - 13,995,333 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2013,849,247 - 13,996,443 (-)EnsemblGRCh38hg38GRCh38
GRCh372013,829,893 - 13,975,979 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362013,778,049 - 13,919,262 (-)NCBINCBI36Build 36hg18NCBI36
Build 342013,778,051 - 13,923,863NCBI
Celera2013,900,109 - 14,046,640 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2013,784,724 - 13,936,185 (-)NCBIHuRef
CHM1_12013,830,052 - 13,975,987 (-)NCBICHM1_1
T2T-CHM13v2.02013,893,057 - 14,044,585 (-)NCBIT2T-CHM13v2.0
Sel1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392140,071,519 - 140,231,644 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2140,071,775 - 140,231,626 (-)EnsemblGRCm39 Ensembl
GRCm382140,229,599 - 140,389,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,229,855 - 140,389,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv372140,055,594 - 140,215,446 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362139,921,299 - 140,081,151 (-)NCBIMGSCv36mm8
Celera2141,415,618 - 141,579,752 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Sel1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,040,624 - 148,167,490 (-)NCBIGRCr8
mRatBN7.23127,586,031 - 127,713,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,586,976 - 127,713,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3131,439,091 - 131,575,563 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,023,193 - 140,159,656 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03137,726,333 - 137,862,787 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,281,809 - 134,406,560 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,281,807 - 134,462,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03140,728,731 - 140,854,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,433,506 - 128,563,511 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13128,339,081 - 128,469,084 (-)NCBI
Celera3126,222,423 - 126,348,674 (-)NCBICelera
Cytogenetic Map3q41NCBI
Sel1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,290,343 - 23,392,429 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541523,290,343 - 23,392,613 (-)NCBIChiLan1.0ChiLan1.0
SEL1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,678,528 - 8,812,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,678,959 - 8,812,370 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,490,252 - 8,623,564 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0249,088,187 - 9,224,513 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1248,690,542 - 8,824,158 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,780,722 - 8,920,621 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0249,135,157 - 9,269,111 (+)NCBIUU_Cfam_GSD_1.0
Sel1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,435,873 - 157,542,369 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364855,867,263 - 5,973,485 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364855,916,463 - 5,975,844 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEL1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,516,558 - 22,627,626 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11722,515,436 - 22,615,444 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,197,502 - 25,307,582 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEL1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1242,731,035 - 42,887,581 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl242,738,577 - 42,825,557 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660543,014,979 - 3,162,824 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sel1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474114,859,905 - 14,986,152 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474114,858,962 - 14,986,830 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000059722   ⟹   ENSPPAP00000036828
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2013,800,212 - 13,945,070 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059729   ⟹   ENSPPAP00000036835
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2013,800,294 - 13,945,061 (-)Ensembl
RefSeq Acc Id: XM_055105074   ⟹   XP_054961049
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22114,740,819 - 14,889,903 (-)NCBI
NHGRI_mPanPan12014,737,650 - 14,886,735 (-)NCBI
RefSeq Acc Id: XM_055105075   ⟹   XP_054961050
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22114,740,819 - 14,889,912 (-)NCBI
NHGRI_mPanPan12014,737,650 - 14,886,744 (-)NCBI
RefSeq Acc Id: XM_055105076   ⟹   XP_054961051
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22114,740,819 - 14,889,919 (-)NCBI
NHGRI_mPanPan12014,737,650 - 14,886,751 (-)NCBI
RefSeq Acc Id: XM_055105077   ⟹   XP_054961052
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22114,740,819 - 14,889,937 (-)NCBI
NHGRI_mPanPan12014,737,650 - 14,886,769 (-)NCBI
RefSeq Acc Id: XM_055105078   ⟹   XP_054961053
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22114,740,819 - 14,889,903 (-)NCBI
NHGRI_mPanPan12014,737,650 - 14,886,735 (-)NCBI
RefSeq Acc Id: XM_055105079   ⟹   XP_054961054
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22114,740,819 - 14,889,903 (-)NCBI
NHGRI_mPanPan12014,737,650 - 14,886,735 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000036835   ⟸   ENSPPAT00000059729
RefSeq Acc Id: ENSPPAP00000036828   ⟸   ENSPPAT00000059722
RefSeq Acc Id: XP_054961052   ⟸   XM_055105077
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054961051   ⟸   XM_055105076
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054961050   ⟸   XM_055105075
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054961054   ⟸   XM_055105079
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054961053   ⟸   XM_055105078
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054961049   ⟸   XM_055105074
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041164 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059722.1 UniProtKB/TrEMBL
  ENSPPAT00000059729.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro Sel1-like UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene SEL1L2 ENTREZGENE
PANTHER PROTEIN SEL-1 HOMOLOG 2 UniProtKB/TrEMBL
  SEL-1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Sel1 UniProtKB/TrEMBL
SMART SEL1 UniProtKB/TrEMBL
Superfamily-SCOP HCP-like UniProtKB/TrEMBL
UniProt A0A2R9C4G8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C7E4_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-11 SEL1L2  SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase  SEL1L2  SEL1L2 adaptor subunit of ERAD E3 ubiquitin ligase  Symbol and/or name change 5135510 APPROVED
2023-03-14 SEL1L2  SEL1L2 adaptor subunit of ERAD E3 ubiquitin ligase  SEL1L2  SEL1L2 adaptor subunit of ERAD E3 ligase  Symbol and/or name change 5135510 APPROVED
2020-07-01 SEL1L2  SEL1L2 adaptor subunit of ERAD E3 ligase  LOC100989420  SEL1L2, ERAD E3 ligase adaptor subunit  Symbol and/or name change 5135510 APPROVED
2020-06-11 LOC100989420  SEL1L2, ERAD E3 ligase adaptor subunit  LOC112437990  protein sel-1 homolog 2-like  Data merged from RGD:13553099 737654 PROVISIONAL
2018-05-08 LOC100989420  SEL1L2, ERAD E3 ligase adaptor subunit  SEL1L2    Symbol and/or name change 5135510 APPROVED
2018-05-01 SEL1L2  SEL1L2, ERAD E3 ligase adaptor subunit    SEL1L2 ERAD E3 ligase adaptor subunit  Symbol and/or name change 5135510 APPROVED