PARP9 (poly(ADP-ribose) polymerase family member 9) - Rat Genome Database

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Gene: PARP9 (poly(ADP-ribose) polymerase family member 9) Pan paniscus
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Symbol: PARP9
Name: poly(ADP-ribose) polymerase family member 9
RGD ID: 11765138
Description: ENCODES a protein that exhibits NAD+ ADP-ribosyltransferase activity (ortholog); NAD+ binding (ortholog); INVOLVED IN DNA damage checkpoint signaling (inferred); double-strand break repair (inferred); negative regulation of DNA-templated transcription (inferred); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH alkaptonuria (ortholog); familial hypocalciuric hypercalcemia (ortholog); Primary Lymphedema with Myelodysplasia (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly [ADP-ribose] polymerase 9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,472,642 - 120,509,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,477,421 - 120,514,085 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,617,722 - 119,655,039 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,522,859 - 126,559,609 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,522,859 - 126,559,647 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PARP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,472,642 - 120,509,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,477,421 - 120,514,085 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,617,722 - 119,655,039 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,522,859 - 126,559,609 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,522,859 - 126,559,647 (-)Ensemblpanpan1.1panPan2
PARP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383122,527,924 - 122,564,784 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3122,527,924 - 122,564,577 (-)EnsemblGRCh38hg38GRCh38
GRCh373122,246,771 - 122,283,631 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,729,461 - 123,766,114 (-)NCBINCBI36Build 36hg18NCBI36
Build 343123,729,462 - 123,766,114NCBI
Celera3120,656,569 - 120,693,333 (-)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3119,620,038 - 119,656,801 (-)NCBIHuRef
CHM1_13122,210,449 - 122,247,205 (-)NCBICHM1_1
T2T-CHM13v2.03125,247,222 - 125,284,030 (-)NCBIT2T-CHM13v2.0
Parp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,759,360 - 35,792,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,758,840 - 35,792,975 (+)EnsemblGRCm39 Ensembl
GRCm381635,938,470 - 35,972,621 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,938,470 - 35,972,605 (+)EnsemblGRCm38mm10GRCm38
MGSCv371635,938,556 - 35,972,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,858,217 - 35,892,352 (+)NCBIMGSCv36mm8
Celera1636,418,713 - 36,452,749 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.43NCBI
Parp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,286,282 - 78,320,409 (-)NCBIGRCr8
mRatBN7.21164,780,977 - 64,814,995 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,780,981 - 64,815,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1173,606,279 - 73,638,748 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,268,543 - 66,301,015 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,299,789 - 65,332,261 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01167,724,071 - 67,758,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,724,076 - 67,756,799 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,812,294 - 70,846,215 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,615,587 - 66,648,294 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,673,175 - 66,702,103 (-)NCBI
Celera1164,246,917 - 64,279,634 (-)NCBICelera
Cytogenetic Map11q22NCBI
Parp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,770,577 - 21,804,717 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,770,158 - 21,806,091 (-)NCBIChiLan1.0ChiLan1.0
PARP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,643,439 - 25,676,979 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,643,883 - 25,677,462 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,667,797 - 25,701,331 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,878,555 - 25,912,166 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,878,555 - 25,912,539 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,675,496 - 25,709,331 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,718,998 - 25,752,634 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,276,577 - 26,310,190 (-)NCBIUU_Cfam_GSD_1.0
Parp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,677,266 - 128,715,188 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,806,818 - 8,840,746 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,806,824 - 8,845,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,966,562 - 138,000,846 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,960,987 - 138,000,862 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213147,581,288 - 147,621,200 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARP9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,297,526 - 58,336,243 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,298,046 - 58,337,124 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,011,893 - 108,049,617 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parp9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912827,547 - 859,199 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912827,112 - 968,501 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000064609   ⟹   ENSPPAP00000041683
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3126,522,859 - 126,559,647 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000064611   ⟹   ENSPPAP00000041685
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3126,523,299 - 126,554,286 (-)Ensembl
RefSeq Acc Id: XM_003825195   ⟹   XP_003825243
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22120,472,642 - 120,508,881 (-)NCBI
NHGRI_mPanPan13120,477,421 - 120,513,695 (-)NCBI
Mhudiblu_PPA_v03119,617,722 - 119,654,021 (-)NCBI
PanPan1.13126,522,859 - 126,558,978 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003825196   ⟹   XP_003825244
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22120,472,642 - 120,509,739 (-)NCBI
NHGRI_mPanPan13120,477,421 - 120,514,085 (-)NCBI
Mhudiblu_PPA_v03119,617,722 - 119,655,035 (-)NCBI
PanPan1.13126,522,859 - 126,559,606 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003825198   ⟹   XP_003825246
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22120,472,642 - 120,509,741 (-)NCBI
NHGRI_mPanPan13120,477,421 - 120,513,972 (-)NCBI
Mhudiblu_PPA_v03119,617,722 - 119,655,039 (-)NCBI
PanPan1.13126,522,859 - 126,559,609 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008950495   ⟹   XP_008948743
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22120,472,642 - 120,508,865 (-)NCBI
NHGRI_mPanPan13120,477,421 - 120,513,659 (-)NCBI
Mhudiblu_PPA_v03119,617,722 - 119,653,987 (-)NCBI
PanPan1.13126,522,859 - 126,558,861 (-)NCBI
Sequence:
RefSeq Acc Id: XR_008624853
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22120,473,330 - 120,508,865 (-)NCBI
NHGRI_mPanPan13120,478,109 - 120,513,661 (-)NCBI
RefSeq Acc Id: XR_008624854
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22120,473,330 - 120,508,865 (-)NCBI
NHGRI_mPanPan13120,478,109 - 120,513,695 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003825243 (Get FASTA)   NCBI Sequence Viewer  
  XP_003825244 (Get FASTA)   NCBI Sequence Viewer  
  XP_003825246 (Get FASTA)   NCBI Sequence Viewer  
  XP_008948743 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041683.1
  ENSPPAP00000041685.1
RefSeq Acc Id: XP_003825246   ⟸   XM_003825198
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CL01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003825244   ⟸   XM_003825196
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CL01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003825243   ⟸   XM_003825195
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CL01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008948743   ⟸   XM_008950495
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CL01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000041683   ⟸   ENSPPAT00000064609
RefSeq Acc Id: ENSPPAP00000041685   ⟸   ENSPPAT00000064611
Protein Domains
Macro   PARP catalytic


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043447 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064609.1 UniProtKB/TrEMBL
  ENSPPAT00000064611.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.220.10 UniProtKB/TrEMBL
  3.90.228.10 UniProtKB/TrEMBL
InterPro Macro_dom UniProtKB/TrEMBL
  Macro_dom-like UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
NCBI Gene PARP9 ENTREZGENE
PANTHER PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 UniProtKB/TrEMBL
Pfam Macro UniProtKB/TrEMBL
PROSITE MACRO UniProtKB/TrEMBL
  PARP_CATALYTIC UniProtKB/TrEMBL
SMART A1pp UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
  SSF52949 UniProtKB/TrEMBL
UniProt A0A2R9CIC9_PANPA UniProtKB/TrEMBL
  A0A2R9CL01 ENTREZGENE, UniProtKB/TrEMBL