GRPEL2 (GrpE like 2, mitochondrial) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: GRPEL2 (GrpE like 2, mitochondrial) Pan paniscus
Analyze
Symbol: GRPEL2
Name: GrpE like 2, mitochondrial
RGD ID: 11760871
Description: ENCODES a protein that exhibits adenyl-nucleotide exchange factor activity (inferred); protein homodimerization activity (inferred); protein-folding chaperone binding (inferred); INVOLVED IN protein folding (inferred); protein import into mitochondrial matrix (inferred); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred); PAM complex, Tim23 associated import motor (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: grpE protein homolog 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24144,575,752 - 144,585,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15142,715,494 - 142,724,786 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05144,771,261 - 144,780,987 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15150,781,671 - 150,791,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5150,781,671 - 150,791,377 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GRPEL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24144,575,752 - 144,585,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15142,715,494 - 142,724,786 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05144,771,261 - 144,780,987 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15150,781,671 - 150,791,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5150,781,671 - 150,791,377 (+)Ensemblpanpan1.1panPan2
GRPEL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385149,345,499 - 149,354,583 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5149,345,430 - 149,354,583 (+)EnsemblGRCh38hg38GRCh38
GRCh375148,725,062 - 148,734,146 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365148,705,170 - 148,714,339 (+)NCBINCBI36Build 36hg18NCBI36
Build 345148,705,284 - 148,714,338NCBI
Celera5144,806,966 - 144,816,121 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5143,871,317 - 143,880,469 (+)NCBIHuRef
CHM1_15148,157,397 - 148,166,568 (+)NCBICHM1_1
T2T-CHM13v2.05149,880,331 - 149,889,398 (+)NCBIT2T-CHM13v2.0
Grpel2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391861,845,495 - 61,860,068 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1861,845,495 - 61,859,396 (-)EnsemblGRCm39 Ensembl
GRCm381861,712,424 - 61,726,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1861,712,424 - 61,726,325 (-)EnsemblGRCm38mm10GRCm38
MGSCv371861,872,078 - 61,885,985 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361861,837,793 - 61,851,700 (-)NCBIMGSCv36mm8
Celera1862,997,997 - 63,011,843 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.69NCBI
Grpel2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81857,438,168 - 57,450,408 (-)NCBIGRCr8
mRatBN7.21855,167,831 - 55,180,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1855,168,209 - 55,180,180 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1857,261,339 - 57,273,589 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01857,975,976 - 57,988,238 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01855,791,694 - 55,803,936 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01857,037,995 - 57,050,234 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1857,036,877 - 57,050,408 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01856,266,330 - 56,278,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41857,691,610 - 57,703,850 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1853,316,882 - 53,329,122 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Grpel2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049558531,442 - 9,278 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049558531,443 - 9,278 (+)NCBIChiLan1.0ChiLan1.0
GRPEL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1459,603,384 - 59,614,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl459,590,167 - 59,614,584 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha459,368,354 - 59,379,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0460,085,904 - 60,097,014 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl460,072,413 - 60,097,107 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1459,872,515 - 59,883,621 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0459,986,909 - 59,997,951 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0460,517,526 - 60,528,629 (-)NCBIUU_Cfam_GSD_1.0
Grpel2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213143,937,230 - 143,948,617 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365045,511,186 - 5,522,614 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365045,511,203 - 5,522,553 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRPEL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2150,511,178 - 150,520,462 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12150,510,520 - 150,520,013 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22157,276,628 - 157,283,071 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRPEL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12351,963,532 - 51,970,251 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603425,773,516 - 25,782,645 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grpel2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247748,702,969 - 8,715,502 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247748,702,833 - 8,713,901 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003829045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000040917   ⟹   ENSPPAP00000018188
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5150,781,671 - 150,791,377 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000040923   ⟹   ENSPPAP00000018194
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5150,782,405 - 150,787,893 (+)Ensembl
RefSeq Acc Id: XM_003829045   ⟹   XP_003829093
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24144,575,752 - 144,585,237 (+)NCBI
NHGRI_mPanPan15142,715,494 - 142,724,786 (+)NCBI
Mhudiblu_PPA_v05144,771,261 - 144,780,987 (+)NCBI
PanPan1.15150,781,671 - 150,791,377 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003829093 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000018188
  ENSPPAP00000018188.1
  ENSPPAP00000018194.1
Reference Protein Sequences
RefSeq Acc Id: XP_003829093   ⟸   XM_003829045
- UniProtKB: A0A2R9AM09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000018188   ⟸   ENSPPAT00000040917
RefSeq Acc Id: ENSPPAP00000018194   ⟸   ENSPPAT00000040923


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032219 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040917.1 UniProtKB/TrEMBL
  ENSPPAT00000040923.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.22.10 UniProtKB/TrEMBL
  3.90.20.20 UniProtKB/TrEMBL
InterPro GrpE UniProtKB/TrEMBL
  GrpE_coiled_coil UniProtKB/TrEMBL
  GrpE_head UniProtKB/TrEMBL
KEGG Report pps:100980721 UniProtKB/TrEMBL
NCBI Gene GRPEL2 ENTREZGENE
PANTHER GRPE PROTEIN HOMOLOG 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR21237 UniProtKB/TrEMBL
Pfam GrpE UniProtKB/TrEMBL
PRINTS GRPEPROTEIN UniProtKB/TrEMBL
PROSITE GRPE UniProtKB/TrEMBL
Superfamily-SCOP SSF51064 UniProtKB/TrEMBL
  SSF58014 UniProtKB/TrEMBL
UniProt A0A2R9AM09 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ATH4_PANPA UniProtKB/TrEMBL